Search Results - "PASCUCCI, B"
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The fine tuning of metabolism, autophagy and differentiation during in vitro myogenesis
Published in Cell death & disease (31-03-2016)“…Although the mechanisms controlling skeletal muscle homeostasis have been identified, there is a lack of knowledge of the integrated dynamic processes…”
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2
The NATO project: nanoparticle-based countermeasures for microgravity-induced osteoporosis
Published in Scientific reports (20-11-2019)“…Recent advances in nanotechnology applied to medicine and regenerative medicine have an enormous and unexploited potential for future space and terrestrial…”
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3
Heterogeneous and self-organizing mineralization of bone matrix promoted by hydroxyapatite nanoparticles
Published in Nanoscale (01-01-2017)“…The mineralization process is crucial to the load-bearing characteristics of the bone extracellular matrix. In this work, we have studied the spatiotemporal…”
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4
Evaluating the size of Fe nanoparticles for ammonia adsorption and dehydrogenation
Published in Computational materials science (01-11-2016)“…[Display omitted] The interaction of NH3 with different Fe clusters and nanoparticles was evaluated using a periodic density functional theory method. The…”
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5
Role of nucleotide excision repair proteins in oxidative DNA damage repair: an updating
Published in Biochemistry (Moscow) (2011)“…DNA repair is a crucial factor in maintaining a low steady-state level of oxidative DNA damage. Base excision repair (BER) has an important role in preventing…”
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6
DNA damage response by single-strand breaks in terminally differentiated muscle cells and the control of muscle integrity
Published in Cell death and differentiation (01-11-2012)“…DNA single-strand breaks (SSB) formation coordinates the myogenic program, and defects in SSB repair in post-mitotic cells have been associated with human…”
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7
The base excision repair: mechanisms and its relevance for cancer susceptibility
Published in Biochimie (01-11-2003)“…Base damage or loss occurs at high frequency in the cells (almost 10 4 bases are damaged and hydrolysed per cell per day). DNA repair is fundamental to…”
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8
Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency
Published in Cell death & disease (01-07-2014)“…Loss of ataxia telangiectasia mutated (ATM) kinase, a key factor of the DNA damage response (DDR) pathway, causes the cancer predisposing and neurodegenerative…”
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9
8-Oxoguanine DNA damage: at the crossroad of alternative repair pathways
Published in Mutation research (29-10-2003)“…Radical oxygen species (ROS) generate various modified DNA bases. Among them 8-oxo-7,8-dihydroguanine (8oxoG) is the most abundant and seems to play a major…”
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10
Comparative density functional theory based study of the reactivity of Cu, Ag, and Au nanoparticles and of (111) surfaces toward CO oxidation and NO2 reduction
Published in Journal of molecular modeling (01-09-2014)“…The reactivity of Cu, Ag, and Au nanoparticles and of the corresponding (111) surfaces of these elements toward CO oxidation and NO 2 reduction has been…”
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11
The accumulation of MMS-induced single strand breaks in G1 phase is recombinogenic in DNA polymerase defective mammalian cells
Published in Nucleic acids research (07-01-2005)Get full text
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12
Reconstitution of the base excision repair pathway for 7,8-dihydro-8-oxoguanine with purified human proteins
Published in Nucleic acids research (15-05-2002)“…In mammalian cells, repair of the most abundant endogenous premutagenic lesion in DNA, 7,8-dihydro-8-oxoguanine (8-oxoG), is initiated by the bifunctional DNA…”
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13
Mammalian base excision repair by DNA polymerases δ and ε
Published in Oncogene (20-08-1998)“…Two distinct pathways for completion of base excision repair (BER) have been discovered in eukaryotes: the DNA polymerase beta (Pol beta)-dependent short-patch…”
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14
DNA polymerase beta is required for efficient DNA strand break repair induced by methyl methanesulfonate but not by hydrogen peroxide
Published in Nucleic acids research (15-08-2000)“…The most frequent DNA lesions in mammalian genomes are removed by the base excision repair (BER) via multiple pathways that involve the replacement of one or…”
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15
DNA repair of UV photoproducts and mutagenesis in human mitochondrial DNA
Published in Journal of molecular biology (24-10-1997)“…The induction and repair of DNA photolesions and mutations in the mitochondrial (mt) DNA of human cells in culture were analysed after cell exposure to UV-C…”
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16
Understanding the effects of metal particle size on the NO2 reduction from a DFT study
Published in Applied surface science (30-09-2019)“…The study of the effect of particle size and low coordination sites in metal nanoparticles (Cun, Agn and Aun with n = 19, 38, 55, 79 and 116) on the reduction…”
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17
Polypropylene reinforced with silicon carbide whiskers
Published in Journal of materials science (01-05-1997)“…Thermal, crystallization and mechanical behaviour of isotactic polypropylene (iPP) reinforced with advanced silicon carbide whiskers (SiCw) has been…”
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18
Long patch base excision repair with purified human proteins. DNA ligase I as patch size mediator for DNA polymerases delta and epsilon
Published in The Journal of biological chemistry (19-11-1999)“…Among the different base excision repair pathways known, the long patch base excision repair of apurinic/apyrimidinic sites is an important mechanism that…”
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Aphidicolin-resistant and -sensitive base excision repair in wild-type and DNA polymerase β-defective mouse cells
Published in DNA repair (02-07-2004)“…Several DNA polymerases (Pols) can add complementary bases at the gap created during the base excision repair (BER). To characterize the BER resynthesis step,…”
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20
Different DNA Polymerases Are Involved in the Short- and Long-Patch Base Excision Repair in Mammalian Cells
Published in Biochemistry (Easton) (17-03-1998)“…Mammalian cells possess two distinct pathways for completion of base excision repair (BER): the DNA polymerase β (Pol β)-dependent short-patch pathway…”
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