Search Results - "PARSONS, P"

Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders by Parsons, Matthew P., Raymond, Lynn A.

“…NMDA receptor (NMDAR)-induced excitotoxicity is thought to contribute to the cell death associated with certain neurodegenerative diseases, stroke, epilepsy,…”
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Huntingtin and the Synapse by Barron, Jessica C., Hurley, Emily P., Parsons, Matthew P.

“…Huntington disease (HD) is a monogenic disease that results in a combination of motor, psychiatric and cognitive symptoms. HD is caused by a CAG trinucleotide…”
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ATP-sensitive potassium channel-mediated lactate effect on orexin neurons: implications for brain energetics during arousal by Parsons, Matthew P, Hirasawa, Michiru

“…Active neurons have a high demand for energy substrate, which is thought to be mainly supplied as lactate by astrocytes. Heavy lactate dependence of neuronal…”
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Plasma receptor for advanced glycation end products and clinical outcomes in acute lung injury by Calfee, C S, Ware, L B, Eisner, M D, Parsons, P E, Thompson, B T, Wickersham, N, Matthay, M A

“…To determine whether baseline plasma levels of the receptor for advanced glycation end products (RAGE), a novel marker of alveolar type I cell injury, are…”
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An Official American Thoracic Society Clinical Practice Guideline: Exercise-induced Bronchoconstriction by PARSONS, Jonathan P, HALLSTRAND, Teal S, ANDERSON, Sandra D, MASTRONARDE, John G, KAMINSKY, David A, RUNDELL, Kenneth W, HULL, James H, STORMS, William W, WEILER, John M, CHEEK, Fern M, WILSON, Kevin C

“…Exercise-induced bronchoconstriction (EIB) describes acute airway narrowing that occurs as a result of exercise. EIB occurs in a substantial proportion of…”
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Phase waves and trigger waves: emergent properties of oscillating and excitable networks in the gut by Parsons, Sean P., Huizinga, Jan D.

“…The gut is enmeshed by a number of cellular networks, but there is only a limited understanding of how these networks generate the complex patterns of activity…”
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Impact of Water Deficiency on Leaf Cuticle Lipids of Arabidopsis by Kosma, Dylan K, Bourdenx, Brice, Bernard, Amélie, Parsons, Eugene P, Lü, Shiyou, Joubès, Jérôme, Jenks, Matthew A

“…Arabidopsis (Arabidopsis thaliana) plants subjected to water deficit, sodium chloride (NaCl), or abscisic acid treatments were shown to exhibit a significant…”
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A myogenic motor pattern in mice lacking myenteric interstitial cells of Cajal explained by a second coupled oscillator network by Parsons, Sean P, Huizinga, Jan D

“…The interstitial cells of Cajal associated with the myenteric plexus (ICC-MP) are a network of coupled oscillators in the small intestine that generate…”
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Real-time imaging of glutamate clearance reveals normal striatal uptake in Huntington disease mouse models by Parsons, Matthew P., Vanni, Matthieu P., Woodard, Cameron L., Kang, Rujun, Murphy, Timothy H., Raymond, Lynn A.

“…It has become well accepted that Huntington disease (HD) is associated with impaired glutamate uptake, resulting in a prolonged time-course of extracellular…”
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Effects of gap junction inhibition on contraction waves in the murine small intestine in relation to coupled oscillator theory by Parsons, Sean P, Huizinga, Jan D

“…Waves of contraction in the small intestine correlate with slow waves generated by the myenteric network of interstitial cells of Cajal. Coupled oscillator…”
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Nitric Oxide Is Essential for Generating the Minute Rhythm Contraction Pattern in the Small Intestine, Likely via ICC-DMP by Parsons, Sean P, Huizinga, Jan D

“…Nitrergic nerves have been proposed to play a critical role in the orchestration of peristaltic activities throughout the gastrointestinal tract. In the…”
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Treerecs: an integrated phylogenetic tool, from sequences to reconciliations by Comte, Nicolas, Morel, Benoit, Hasić, Damir, Guéguen, Laurent, Boussau, Bastien, Daubin, Vincent, Penel, Simon, Scornavacca, Celine, Gouy, Manolo, Stamatakis, Alexandros, Tannier, Eric, Parsons, David P

“…Abstract Motivation Gene and species tree reconciliation methods are used to interpret gene trees, root them and correct uncertainties that are due to scarcity…”
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Network properties of interstitial cells of Cajal affect intestinal pacemaker activity and motor patterns, according to a mathematical model of weakly coupled oscillators by Wei, Ruihan, Parsons, Sean P., Huizinga, Jan D.

“…New Findings What is the central question of this study? What are the effects of interstitial cells of Cajal (ICC) network perturbations on intestinal…”
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Dose–Volume Predictors for Patient-reported Late Diarrhoea, Faecal Incontinence and Urgency after Pelvic Radiotherapy by Jadon, R., Hanna, L., Parsons, P., Staffurth, J.

“…Pelvic radiotherapy adds significantly to the curative treatment of many pelvic malignancies. However, this cure comes at a cost for many patients, where late…”
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High-fat diet induces time-dependent synaptic plasticity of the lateral hypothalamus by Linehan, Victoria, Fang, Lisa Z., Parsons, Matthew P., Hirasawa, Michiru

“…Orexin (ORX) and melanin-concentrating hormone (MCH) neurons in the lateral hypothalamus are critical regulators of energy homeostasis and are thought to…”
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Arabidopsis ECERIFERUM9 Involvement in Cuticle Formation and Maintenance of Plant Water Status by Lü, Shiyou, Zhao, Huayan, Des Marais, David L., Parsons, Eugene P., Wen, Xiaoxue, Xu, Xiaojing, Bangarusamy, Dhinoth K., Wang, Guangchao, Rowland, Owen, Juenger, Thomas, Bressan, Ray A., Jenks, Matthew A.

“…Mutation of the ECERIFERUM9 (CER9) gene in Arabidopsis (Arabidopsis thaliana) causes elevated amounts of 18-carbon-length cutin monomers and a dramatic shift…”
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Super-resolution imaging reveals extrastriatal synaptic dysfunction in presymptomatic Huntington disease mice by Ravalia, Adam S., Lau, James, Barron, Jessica C., Purchase, Stephanie L.M., Southwell, Amber L., Hayden, Michael R., Nafar, Firoozeh, Parsons, Matthew P.

“…Synaptic structure and function are compromised prior to cell death and symptom onset in a variety of neurodegenerative diseases. In Huntington disease (HD), a…”
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Local network regulation of orexin neurons in the lateral hypothalamus by Burt, Julia, Alberto, Christian O, Parsons, Matthew P, Hirasawa, Michiru

“…Obesity and inadequate sleep are among the most common causes of health problems in modern society. Thus, the discovery that orexin (hypocretin) neurons play a…”
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The origin of segmentation motor activity in the intestine by Huizinga, Jan D., Chen, Ji-Hong, Fang Zhu, Yong, Pawelka, Andrew, McGinn, Ryan J., Bardakjian, Berj L., Parsons, Sean P., Kunze, Wolfgang A., Wu, Richard You, Bercik, Premysl, Khoshdel, Amir, Chen, Sifeng, Yin, Sheng, Zhang, Qian, Yu, Yuanjie, Gao, Qingmin, Li, Kongling, Hu, Xinghai, Zarate, Natalia, Collins, Phillip, Pistilli, Marc, Ma, Junling, Zhang, Ruixue, Chen, David

“…The segmentation motor activity of the gut that facilitates absorption of nutrients was first described in the late 19th century, but the fundamental…”
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Impaired development of cortico-striatal synaptic connectivity in a cell culture model of Huntington's disease by Buren, Caodu, Parsons, Matthew P, Smith-Dijak, Amy, Raymond, Lynn A

“…Abstract Huntington's disease (HD) is a genetically inherited neurodegenerative disease caused by a mutation in the gene encoding the huntingtin protein. This…”
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