Search Results - "PARNAUD, Geraldine"

Blockade of β1 Integrin–Laminin-5 Interaction Affects Spreading and Insulin Secretion of Rat β-Cells Attached on Extracellular Matrix by PARNAUD, Geraldine, HAMMAR, Eva, ROUILLER, Dominique G, ARMANET, Mathieu, HALBAN, Philippe A, BOSCO, Domenico

“…Blockade of β1 Integrin–Laminin-5 Interaction Affects Spreading and Insulin Secretion of Rat β-Cells Attached on Extracellular Matrix Geraldine Parnaud 1 , Eva…”
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Survival of free and encapsulated human and rat islet xenografts transplanted into the mouse bone marrow by Meier, Raphael P H, Seebach, Jörg D, Morel, Philippe, Mahou, Redouan, Borot, Sophie, Giovannoni, Laurianne, Parnaud, Geraldine, Montanari, Elisa, Bosco, Domenico, Wandrey, Christine, Berney, Thierry, Bühler, Leo H, Muller, Yannick D

“…Bone marrow was recently proposed as an alternative and potentially immune-privileged site for pancreatic islet transplantation. The aim of the present study…”
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Rab GTPase-Activating Protein AS160 Is a Major Downstream Effector of Protein Kinase B/Akt Signaling in Pancreatic β-Cells by BOUZAKRI, Karim, RIBAUX, Pascale, TOMAS, Alejandra, PARNAUD, Geraldine, RICKENBACH, Katharina, HALBAN, Philippe A

“…Rab GTPase-Activating Protein AS160 Is a Major Downstream Effector of Protein Kinase B/Akt Signaling in Pancreatic β-Cells Karim Bouzakri , Pascale Ribaux ,…”
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Computer-Assisted Digital Image Analysis to Quantify the Mass and Purity of Isolated Human Islets Before Transplantation by NICLAUSS, Nadja, SGROI, Antonino, MOREL, Philippe, BAERTSCHIGER, Reto, ARMANET, Mathieu, WOJTUSCISZYN, Anne, PARNAUD, Geraldine, MULLER, Yannick, BERNEY, Thierry, BOSCO, Domenico

“…Accurate determination of islet purity and mass before transplantation is an essential part of quality control. The standard method is based on manual…”
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Engineering of Primary Pancreatic Islet Cell Spheroids for Three-dimensional Culture or Transplantation: A Methodological Comparative Study by Wassmer, Charles-Henri, Bellofatto, Kevin, Perez, Lisa, Lavallard, Vanessa, Cottet-Dumoulin, David, Ljubicic, Sanda, Parnaud, Géraldine, Bosco, Domenico, Berishvili, Ekaterine, Lebreton, Fanny

“…Three-dimensional (3D) cell culture by engineering spheroids has gained increasing attention in recent years because of the potential advantages of such…”
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Unique Arrangement of α- and β-Cells in Human Islets of Langerhans by BOSCO, Domenico, ARMANET, Mathieu, MOREL, Philippe, NICLAUSS, Nadja, SGROI, Antonino, MULLER, Yannick D, GIOVANNONI, Laurianne, PARNAUD, Géraldine, BERNEY, Thierry

“…It is generally admitted that the endocrine cell organization in human islets is different from that of rodent islets. However, a clear description of human…”
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Increased Interleukin (IL)-1β Messenger Ribonucleic Acid Expression in β-Cells of Individuals with Type 2 Diabetes and Regulation of IL-1β in Human Islets by Glucose and Autostimulation by Böni-Schnetzler, Marianne, Thorne, Jeffrey, Parnaud, Géraldine, Marselli, Lorella, Ehses, Jan A., Kerr-Conte, Julie, Pattou, Francois, Halban, Philippe A., Weir, Gordon C., Donath, Marc Y.

“…Context: Elevated glucose levels impair islet function and survival, and it has been proposed that intraislet expression of IL-1β contributes to glucotoxicity…”
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NLRP3 inflammasome is expressed and regulated in human islets by Lebreton, Fanny, Berishvili, Ekaterine, Parnaud, Géraldine, Rouget, Caroline, Bosco, Domenico, Berney, Thierry, Lavallard, Vanessa

“…NRLP3 inflammasome is a protein complex involved in the maturation of IL1β. In the onset of type 1 diabetes as well as in islet transplantation, IL-1β is one…”
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Identification of newly synthetized proteins by mass spectrometry to understand palmitate-induced early cellular changes in pancreatic islets by Cottet-Dumoulin, David, Fonseca, Laura Mar, Bignard, Juliette, Hanna, Reine, Parnaud, Géraldine, Lebreton, Fanny, Bellofatto, Kevin, Berishvili, Ekaterine, Berney, Thierry, Bosco, Domenico

“…Obesity and lipid metabolism dysregulation are often associated with insulin resistance, and can lead to type 2 diabetes. However, mechanisms linking insulin…”
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NLRP3 Inflammasome is Activated in Rat Pancreatic Islets by Transplantation and Hypoxia by Lavallard, Vanessa, Cottet-Dumoulin, David, Wassmer, Charles-Henri, Rouget, Caroline, Parnaud, Géraldine, Brioudes, Estelle, Lebreton, Fanny, Bellofatto, Kevin, Berishvili, Ekaterine, Berney, Thierry, Bosco, Domenico

“…Hypoxia, IL-1β production and oxidative stress are involved in islet graft dysfunction and destruction. However, the link between these events has not yet been…”
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Biosynthetic Activity Differs Between Islet Cell Types and in Beta Cells Is Modulated by Glucose and Not by Secretion by Cottet-Dumoulin, David, Lavallard, Vanessa, Lebreton, Fanny, Wassmer, Charles H, Bellofatto, Kevin, Parnaud, Géraldine, Berishvili, Ekaterine, Berney, Thierry, Bosco, Domenico

“…A correct biosynthetic activity is thought to be essential for the long-term function and survival of islet cells in culture and possibly also after islet…”
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MicroRNAs contribute to compensatory β cell expansion during pregnancy and obesity by Jacovetti, Cécile, Abderrahmani, Amar, Parnaud, Géraldine, Jonas, Jean-Christophe, Peyot, Marie-Line, Cornu, Marion, Laybutt, Ross, Meugnier, Emmanuelle, Rome, Sophie, Thorens, Bernard, Prentki, Marc, Bosco, Domenico, Regazzi, Romano

“…Pregnancy and obesity are frequently associated with diminished insulin sensitivity, which is normally compensated for by an expansion of the functional β cell…”
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Intercellular contacts affect secretion and biosynthesis of pancreatic islet cells by Cottet-Dumoulin, David, Perrier, Quentin, Lavallard, Vanessa, Matthey-Doret, David, Fonseca, Laura Mar, Bignard, Juliette, Hanna, Reine, Parnaud, Géraldine, Lebreton, Fanny, Bellofatto, Kevin, Berishvili, Ekaterine, Berney, Thierry, Bosco, Domenico

“…Cell protein biosynthesis is regulated by different factors, but implication of intercellular contacts on alpha and beta cell protein biosyntheses activity has…”
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Shielding islets with human amniotic epithelial cells enhances islet engraftment and revascularization in a murine diabetes model by Lebreton, Fanny, Bellofatto, Kevin, Wassmer, Charles H., Perez, Lisa, Lavallard, Vanessa, Parnaud, Géraldine, Cottet‐Dumoulin, David, Kerr‐Conte, Julie, Pattou, François, Bosco, Domenico, Othenin‐Girard, Véronique, Martinez de Tejada, Begoña, Berishvili, Ekaterine

“…Hypoxia is a major cause of considerable islet loss during the early posttransplant period. Here, we investigate whether shielding islets with human amniotic…”
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Cell rearrangement in transplanted human islets by Lavallard, Vanessa, Armanet, Mathieu, Parnaud, Geraldine, Meyer, Jérémy, Barbieux, Charlotte, Montanari, Elisa, Meier, Raphaël, Morel, Philippe, Berney, Thierry, Bosco, Domenico

“…The major feature of the human pancreatic islet architecture is the organization of endocrine cells into clusters comprising central β cells and peripheral α…”
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Impact of ischemia time on islet isolation success and posttransplantation outcomes: A retrospective study of 452 pancreas isolations by Wassmer, Charles‐Henri, Perrier, Quentin, Combescure, Christophe, Pernin, Nadine, Parnaud, Géraldine, Cottet‐Dumoulin, David, Brioudes, Estelle, Bellofatto, Kevin, Lebreton, Fanny, Berishvili, Ekaterine, Lablanche, Sandrine, Kessler, Laurence, Wojtusciszyn, Anne, Buron, Fanny, Borot, Sophie, Bosco, Domenico, Berney, Thierry, Lavallard, Vanessa

“…Many variables impact islet isolation, including pancreas ischemia time. The ischemia time upper limit that should be respected to avoid a negative impact on…”
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Multicenter Assessment of Animal-free Collagenase AF-1 for Human Islet Isolation by Brandhorst, Daniel, Parnaud, Géraldine, Friberg, Andrew, Lavallard, Vanessa, Demuylder-Mischler, Sandrine, Hughes, Stephen, Saphörster, Julia, Kurfürst, Manfred, Korsgren, Olle, Berney, Thierry, Johnson, Paul R. V.

“…Animal-free (AF) SERVA Collagenase AF-1 and Neutral Protease (NP) AF GMP Grade have recently become available for human islet isolation. This report describes…”
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Signaling Pathways Implicated in the Stimulation of β-Cell Proliferation by Extracellular Matrix by Parnaud, Géraldine, Hammar, Eva, Ribaux, Pascale, Donath, Marc Y, Berney, Thierry, Halban, Philippe A

“…Laminin-5-rich extracellular matrix derived from 804G cells (804G-ECM) induces spreading, improves glucose-stimulated insulin secretion, and increases survival…”
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Influence of Donor Age on Islet Isolation and Transplantation Outcome by NICLAUSS, Nadja, BOSCO, Domenico, MEIER, Raphael, TOSO, Christian, BADET, Lionel, BENHAMOU, Pierre-Yves, BERNEY, Thierry, MOREL, Philippe, DEMUYLDER-MISCHLER, Sandrine, BRAULT, Coralie, MILLIAT-GUITTARD, Laure, COLIN, Cyrille, PARNAUD, Geraldine, MULLER, Yannick D, GIOVANNONI, Laurianne

“…It has been suggested that the age of human organ donors might influence islet isolation and transplantation outcome in a negative way due to a decrease of in…”
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Cadherin Engagement Protects Human β-Cells from Apoptosis by Parnaud, Géraldine, Gonelle-Gispert, Carmen, Morel, Philippe, Giovannoni, Laurianne, Muller, Yannick D, Meier, Raphael, Borot, Sophie, Berney, Thierry, Bosco, Domenico

“…The aim of this study was to assess the expression of different types of cadherins in human islets and their role in human β-cell apoptosis. Expression of E-,…”
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