Search Results - "PARKS, Griffith D"

Complement Inhibitors Vitronectin and Clusterin Are Recruited from Human Serum to the Surface of Coronavirus OC43-Infected Lung Cells through Antibody-Dependent Mechanisms by Fox, Candace R, Parks, Griffith D

“…Little is known about the role of complement (C') in infections with highly prevalent circulating human coronaviruses such as OC43, a group of viruses of major…”
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Delivery of a novel membrane-anchored Fc chimera enhances NK cell-mediated killing of tumor cells and persistently virus-infected cells by Varudkar, Namita, Shiffer, Elisabeth M, Oyer, Jeremiah L, Copik, Alicja, Parks, Griffith D

“…Antibody-dependent cellular cytotoxicity (ADCC) is one of the most powerful mechanisms for Natural Killer (NK) cells to kill cancer cells or virus-infected…”
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Histone Deacetylase Inhibitors Enhance Cell Killing and Block Interferon-Beta Synthesis Elicited by Infection with an Oncolytic Parainfluenza Virus by Fox, Candace R, Parks, Griffith D

“…Previous results have shown that infection with the cytoplasmic-replicating parainfluenza virus 5 mutant P/V-CPI- sensitizes cells to DNA damaging agents,…”
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Broad-Spectrum, Potent, and Durable Ceria Nanoparticles Inactivate RNA Virus Infectivity by Targeting Virion Surfaces and Disrupting Virus-Receptor Interactions by Fox, Candace R, Kedarinath, Kritika, Neal, Craig J, Sheiber, Jeremy, Kolanthai, Elayaraja, Kumar, Udit, Drake, Christina, Seal, Sudipta, Parks, Griffith D

“…There is intense interest in developing long-lasting, potent, and broad-spectrum antiviral disinfectants. Ceria nanoparticles (CNPs) can undergo surface redox…”
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Parainfluenza Virus 5 V Protein Blocks Interferon Gamma-Mediated Upregulation of NK Cell Inhibitory Ligands and Improves NK Cell Killing of Neuroblastoma Cells by Shiffer, Elisabeth M, Oyer, Jeremiah L, Copik, Alicja J, Parks, Griffith D

“…Natural killer (NK) cells can be effective immunotherapeutic anti-cancer agents due to their ability to selectively target and kill tumor cells. This activity…”
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Relative Contribution of Cellular Complement Inhibitors CD59, CD46, and CD55 to Parainfluenza Virus 5 Inhibition of Complement-Mediated Neutralization by Li, Yujia, Parks, Griffith D

“…The complement system is a part of the innate immune system that viruses need to face during infections. Many viruses incorporate cellular regulators of…”
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Paramyxovirus Activation and Inhibition of Innate Immune Responses by Parks, Griffith D., Alexander-Miller, Martha A.

“…Paramyxoviruses represent a remarkably diverse family of enveloped nonsegmented negative-strand RNA viruses, some of which are the most ubiquitous…”
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Oncolytic parainfluenza virus combines with NK cells to mediate killing of infected and non-infected lung cancer cells within 3D spheroids: role of type I and type III interferon signaling by Varudkar, Namita, Oyer, Jeremiah L, Copik, Alicja, Parks, Griffith D

“…BackgroundThere is intense interest in developing novel oncolytic viruses, which can be used in cancer therapies along with immune cells such as natural killer…”
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Differential In Vitro Growth and Cell Killing of Cancer versus Benign Prostate Cells by Oncolytic Parainfluenza Virus by Kedarinath, Kritika, Parks, Griffith D

“…The development of effective oncolytic viruses will require understanding the differences in virus replication and killing between normal and cancer cells…”
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Zika virus as an oncolytic treatment of human neuroblastoma cells requires CD24 by Mazar, Joseph, Li, Yujia, Rosado, Amy, Phelan, Peter, Kedarinath, Kritika, Parks, Griffith D, Alexander, Kenneth A, Westmoreland, Tamarah J

“…Neuroblastoma is the second most common childhood tumor. Survival is poor even with intensive therapy. In a search for therapies to neuroblastoma, we assessed…”
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La Crosse Virus Infection of Human Keratinocytes Leads to Interferon-Dependent Apoptosis of Bystander Non-Infected Cells In Vitro by Cruz, Maria A, Parks, Griffith D

“…Resident cells in the skin serve as the first innate line of defense against insect-borne pathogens, but the role of these cell types in promoting or limiting…”
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CD24 Expression Dampens the Basal Antiviral State in Human Neuroblastoma Cells and Enhances Permissivity to Zika Virus Infection by Kedarinath, Kritika, Fox, Candace R, Crowgey, Erin, Mazar, Joseph, Phelan, Peter, Westmoreland, Tamarah J, Alexander, Kenneth A, Parks, Griffith D

“…Zika virus (ZIKV) exhibits distinct selectivity for infection of various cells and tissues, but how host cellular factors modulate varying permissivity remains…”
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Incorporation of Host Complement Regulatory Proteins into Newcastle Disease Virus Enhances Complement Evasion by BISWAS, Moanaro, JOHNSON, John B, KUMAR, Sandeep R. P, PARKS, Griffith D, SUBBIAH, Elankumaran

“…Errata ( vol. 87 , p. 1287 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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Virion-Associated Complement Regulator CD55 Is More Potent than CD46 in Mediating Resistance of Mumps Virus and Vesicular Stomatitis Virus to Neutralization by Johnson, John B, Lyles, Douglas S, Alexander-Miller, Martha A, Parks, Griffith D

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An AGM model for changes in complement during pregnancy: neutralization of influenza virus by serum is diminished in late third trimester by Mayer, Anne E, Parks, Griffith D

“…Pregnant women in the third trimester are at increased risk of severe influenza disease relative to the general population, though mechanisms behind this are…”
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Antiviral activity and RNA polymerase degradation following Hsp90 inhibition in a range of negative strand viruses by Connor, John H, McKenzie, Margie O, Parks, Griffith D, Lyles, Douglas S

“…Abstract We have analyzed the effectiveness of Hsp90 inhibitors in blocking the replication of negative-strand RNA viruses. In cells infected with the…”
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Point Mutations in the Paramyxovirus F Protein That Enhance Fusion Activity Shift the Mechanism of Complement-Mediated Virus Neutralization by Johnson, John B, Schmitt, Anthony P, Parks, Griffith D

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The Paramyxoviruses Simian Virus 5 and Mumps Virus Recruit Host Cell CD46 To Evade Complement-Mediated Neutralization by JOHNSON, John B, GRANT, Ken, PARKS, Griffith D

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Role for the Paramyxovirus Genomic Promoter in Limiting Host Cell Antiviral Responses and Cell Killing by MANUSE, Mary J, PARKS, Griffith D

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Role for the Phosphoprotein P Subunit of the Paramyxovirus Polymerase in Limiting Induction of Host Cell Antiviral Responses by DILLON, Patrick J, PARKS, Griffith D

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