Search Results - "PARKER, D. K"

Meis1 establishes the pre-hemogenic endothelial state prior to Runx1 expression by Coulombe, Patrick, Cole, Grace, Fentiman, Amanda, Parker, Jeremy D. K., Yung, Eric, Bilenky, Misha, Degefie, Lemlem, Lac, Patrick, Ling, Maggie Y. M., Tam, Derek, Humphries, R. Keith, Karsan, Aly

“…Hematopoietic stem and progenitor cells (HSPCs) originate from an endothelial-to-hematopoietic transition (EHT) during embryogenesis. Characterization of early…”
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Phylogenetic analysis and delineation of phytoplasmas based on secY gene sequences by LEE, I.-M, BOTTNER-PARKER, K. D, ZHAO, Y, DAVIS, R. E, HARRISON, N. A

“…The secY gene sequence is more variable than that of the 16S rRNA gene. Comparative phylogenetic analyses with 16S rRNA and secY gene sequences from 80 and 83…”
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Differentiation and classification of phytoplasmas in the pigeon pea witches’-broom group (16SrIX): an update based on multiple gene sequence analysis by Lee, I.-M, Bottner-Parker, K. D, Zhao, Y, Bertaccini, A, Davis, R. E

“…The pigeon pea witches’-broom phytoplasma group (16SrIX) comprises diverse strains that cause numerous diseases in leguminous trees and herbaceous crops,…”
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‘Candidatus Phytoplasma costaricanum’ a novel phytoplasma associated with an emerging disease in soybean (Glycine max) by Lee, I.-M, Bottner-Parker, K. D, Zhao, Y, Villalobos, W, Moreira, L

“…A novel phytoplasma, designated strain SoyST1c1, associated with a newly emerging disease in soybean (Glycine max), known as soybean stunt (SoyST), was found…”
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A clinical transcriptome approach to patient stratification and therapy selection in acute myeloid leukemia by Docking, T. Roderick, Parker, Jeremy D. K., Jädersten, Martin, Duns, Gerben, Chang, Linda, Jiang, Jihong, Pilsworth, Jessica A., Swanson, Lucas A., Chan, Simon K., Chiu, Readman, Nip, Ka Ming, Mar, Samantha, Mo, Angela, Wang, Xuan, Martinez-Høyer, Sergio, Stubbins, Ryan J., Mungall, Karen L., Mungall, Andrew J., Moore, Richard A., Jones, Steven J. M., Birol, İnanç, Marra, Marco A., Hogge, Donna, Karsan, Aly

“…As more clinically-relevant genomic features of myeloid malignancies are revealed, it has become clear that targeted clinical genetic testing is inadequate for…”
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Phylogenetic analysis of the Neks reveals early diversification of ciliary-cell cycle kinases by Parker, Jeremy D K, Bradley, Brian A, Mooers, Arne O, Quarmby, Lynne M

“…NIMA-related kinases (Neks) have been studied in diverse eukaryotes, including the fungus Aspergillus and the ciliate Tetrahymena. In the former, a single Nek…”
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Functional interactions between the ciliopathy-associated Meckel syndrome 1 (MKS1) protein and two novel MKS1-related (MKSR) proteins by Bialas, Nathan J, Inglis, Peter N, Li, Chunmei, Robinson, Jon F, Parker, Jeremy D.K, Healey, Michael P, Davis, Erica E, Inglis, Chrystal D, Toivonen, Tiina, Cottell, David C, Blacque, Oliver E, Quarmby, Lynne M, Katsanis, Nicholas, Leroux, Michel R

“…Meckel syndrome (MKS) is a ciliopathy characterized by encephalocele, cystic renal disease, liver fibrosis and polydactyly. An identifying feature of MKS1, one…”
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Effect of preexamination conditions in a centralized-testing model of non-invasive prenatal screening by Fibke, Chad, Giroux, Sylvie, Caron, André, Starks, Elizabeth, Parker, Jeremy D K, Swanson, Lucas, Jouan, Loubna, Langlois, Sylvie, Rouleau, Guy, Rousseau, François, Karsan, Aly

“…Non-invasive prenatal testing requires the presence of fetal DNA in maternal plasma. Understanding how preexamination conditions affect the integrity of…”
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Bifidobacterium longum -fermented rice bran and rice bran supplementation affects the gut microbiome and metabolome by Nealon, N J, Parker, K D, Lahaie, P, Ibrahim, H, Maurya, A K, Raina, K, Ryan, E P

“…This study investigated gut microbiota composition along with food, host, and microbial derived metabolites in the colon and systemic circulation of healthy…”
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Characterization and molecular differentiation of 16SrI-E and 16SrIX-E phytoplasmas associated with blueberry stunt disease in New Jersey by Bagadia, P.G., Polashock, J., Bottner-Parker, K.D., Zhao, Y., Davis, R.E., Lee, I.-M.

“…A nested PCR assay was employed to detect the presence of phytoplasmas in 127 blueberry plants exhibiting typical or a portion of blueberry stunt (BBS)…”
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Cilia and the cell cycle? by Quarmby, Lynne M, Parker, Jeremy D.K

“…A recent convergence of data indicating a relationship between cilia and proliferative diseases, such as polycystic kidney disease, has revived the…”
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New subgroup 16SrIII-Y phytoplasmas associated with false-blossom diseased cranberry (Vaccinium macrocarpon) plants and with known and potential insect vectors in New Jersey by Lee, I.-M., Polashock, J., Bottner-Parker, K. D., Bagadia, P. G., Rodriguez-Saona, C., Zhao, Y., Davis, R. E.

“…The identity of the presumed phytoplasmal pathogen associated with cranberry false-blossom disease has never been fully clarified. In the present study a…”
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Draft Genome Sequence of "Candidatus Phytoplasma pruni" Strain CX, a Plant-Pathogenic Bacterium by Lee, I-M, Shao, J, Bottner-Parker, K D, Gundersen-Rindal, D E, Zhao, Y, Davis, R E

“…"Candidatus Phytoplasma pruni" strain CX, belonging to subgroup 16SrIII-A, is a plant-pathogenic bacterium causing economically important diseases in many…”
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Barnacle: detecting and characterizing tandem duplications and fusions in transcriptome assemblies by Swanson, Lucas, Robertson, Gordon, Mungall, Karen L, Butterfield, Yaron S, Chiu, Readman, Corbett, Richard D, Docking, T Roderick, Hogge, Donna, Jackman, Shaun D, Moore, Richard A, Mungall, Andrew J, Nip, Ka Ming, Parker, Jeremy D K, Qian, Jenny Qing, Raymond, Anthony, Sung, Sandy, Tam, Angela, Thiessen, Nina, Varhol, Richard, Wang, Sherry, Yorukoglu, Deniz, Zhao, Yongjun, Hoodless, Pamela A, Sahinalp, S Cenk, Karsan, Aly, Birol, Inanc

“…Chimeric transcripts, including partial and internal tandem duplications (PTDs, ITDs) and gene fusions, are important in the detection, prognosis, and…”
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Generation of an induced pluripotent stem cell line from a patient with conduction disease and recurrent ventricular fibrillation with a sodium voltage-gated channel alpha subunit 5 (SCN5A) gene c.392 + 3A > G splice-site variant by Li, Serena, Fraser, Stuart, Ranpura, Ginell, Lim, Seakcheng, Singer, Emma S., Parker, Jeremy D.K., Crowe, Joshua, Bagnall, Richard D., Laksman, Zachary, Semsarian, Christopher

“…Variants in the sodium voltage-gated channel alpha subunit 5 gene (SCN5A) produce variable cardiac phenotypes including Brugada syndrome, conduction disease…”
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Molecular etiology of an indolent lymphoproliferative disorder determined by whole-genome sequencing by Parker, Jeremy D K, Shen, Yaoqing, Pleasance, Erin, Li, Yvonne, Schein, Jacqueline E, Zhao, Yongjun, Moore, Richard, Wegrzyn-Woltosz, Joanna, Savage, Kerry J, Weng, Andrew P, Gascoyne, Randy D, Jones, Steven, Marra, Marco, Laskin, Janessa, Karsan, Aly

“…In an attempt to assess potential treatment options, whole-genome and transcriptome sequencing were performed on a patient with an unclassifiable small…”
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Endothelial Sash1 Is Required for Lung Maturation through Nitric Oxide Signaling by Coulombe, Patrick, Paliouras, Grigorios N., Clayton, Ashley, Hussainkhel, Angela, Fuller, Megan, Jovanovic, Vida, Dauphinee, Shauna, Umlandt, Patricia, Xiang, Ping, Kyle, Alistair H., Minchinton, Andrew I., Humphries, R. Keith, Hoodless, Pamela A., Parker, Jeremy D.K., Wright, Joanne L., Karsan, Aly

“…The sterile alpha motif (SAM) and SRC homology 3 (SH3) domain containing protein 1 (Sash1) acts as a scaffold in TLR4 signaling. We generated Sash1−/− mice,…”
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Use of Treatment-Focused Tumor Sequencing to Screen for Germline Cancer Predisposition by Lau, Tammy T.Y., May, Christina M., Sefid Dashti, Zahra J., Swanson, Lucas, Starks, Elizabeth R., Parker, Jeremy D.K., Moore, Richard A., Tucker, Tracy, Bosdet, Ian, Young, Sean S., Santos, Jennifer L., Compton, Katie, Heidary, Nili, Hoang, Lien, Schrader, Kasmintan A., Sun, Sophie, Kwon, Janice S., Tinker, Anna V., Karsan, Aly

“…Next-generation sequencing assays are capable of identifying cancer patients eligible for targeted therapies and can also detect germline variants associated…”
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Variables Associated With Adolescent Alcohol Use: A Multiethnic Comparison by Parker, Keith D., Calhoun, Thomas, Weaver, Greg

“…The authors examined the influence of sociodemographic variables on the frequency and intensity of alcohol use among a nationally representative sample of…”
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Fixation Effects on Variant Calling in a Clinical Resequencing Panel by Parker, Jeremy D.K., Yap, Shyong Quin, Starks, Elizabeth, Slind, Jillian, Swanson, Lucas, Docking, T. Roderick, Fuller, Megan, Zhou, Chen, Walker, Blair, Filipenko, Douglas, Xiong, Wei, Karimuddin, Ahmer A., Phang, P. Terry, Raval, Manoj, Brown, Carl J., Karsan, Aly

“…Formalin fixation is the standard method for the preservation of tissue for diagnostic purposes, including pathologic review and molecular assays. However,…”
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