Search Results - "PARK, W"
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Phase II study of ceralasertib (AZD6738) in combination with durvalumab in patients with advanced/metastatic melanoma who have failed prior anti-PD-1 therapy
Published in Annals of oncology (01-02-2022)“…Modulating the DNA damage response and repair (DDR) pathways is a promising strategy for boosting cancer immunotherapy. Ceralasertib (AZD6738) is an oral…”
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HLA-corrected tumor mutation burden and homologous recombination deficiency for the prediction of response to PD-(L)1 blockade in advanced non-small-cell lung cancer patients
Published in Annals of oncology (01-07-2020)“…Immune checkpoint inhibitors (ICIs) have been shown to be beneficial for some patients with advanced non-small-cell lung cancer (NSCLC). However, the…”
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3
Chronic chorioamnionitis is the most common placental lesion in late preterm birth
Published in Placenta (Eastbourne) (01-08-2013)“…Abstract Objectives The pathogenesis of late preterm birth remains elusive for the mechanisms of disease responsible. Placental examination can often provide…”
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Randomized clinical trial of immersive virtual reality tour of the operating theatre in children before anaesthesia
Published in British journal of surgery (01-11-2017)“…Background A virtual reality (VR) tour of the operating theatre before anaesthesia could provide a realistic experience for children. This study was designed…”
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5
Randomized controlled trial to investigate the effects of a newly developed formulation of phentermine diffuse-controlled release for obesity
Published in Diabetes, obesity & metabolism (01-10-2010)“…Aim: To evaluate the efficacy and safety of a newly developed formulation of phentermine diffuse-controlled release (DCR) in patients with obesity. Methods:…”
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6
Ensemble global warming simulations with idealized Antarctic meltwater input
Published in Climate dynamics (01-03-2019)“…The Earth will exhibit continued global surface warming in response to a sustained increase of atmospheric carbon dioxide (CO 2 ) levels. Massive meltwater…”
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Decline in extractable antibiotics in manure-based composts during composting
Published in Waste management (Elmsford) (2012)“…► The study examined effect of composting operation on decline of veterinary antibiotics (VAs) sourced from animal manure. ► The organic matter provided a wide…”
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Managerial Learning from Analyst Feedback to Voluntary Capex Guidance, Investment Efficiency, and Firm Performance
Published in Management science (01-01-2022)“…We test predictions that managers issuing voluntary capex guidance learn from analyst feedback and that this learning enhances investment efficiency and firm…”
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Review: Semiconductor Piezoresistance for Microsystems
Published in Proceedings of the IEEE (01-03-2009)“…Piezoresistive sensors are among the earliest micromachined silicon devices. The need for smaller, less expensive, higher performance sensors helped drive…”
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10
Dynamic modelling of customer preferences for product design using DENFIS and opinion mining
Published in Advanced engineering informatics (01-10-2019)“…Previous studies mainly employed customer surveys to collect survey data for understanding customer preferences on products and developing customer preference…”
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Detection of microorganisms using terahertz metamaterials
Published in Scientific reports (16-05-2014)“…Microorganisms such as fungi and bacteria cause many human diseases and therefore rapid and accurate identification of these substances is essential for…”
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The effect of 5Hz high‐frequency rTMS over contralesional pharyngeal motor cortex in post‐stroke oropharyngeal dysphagia: a randomized controlled study
Published in Neurogastroenterology and motility (01-04-2013)“…Background We sought to find the therapeutic effect of 5Hz high‐frequency repetitive transcranial magnetic stimulation (rTMS) over the unaffected pharyngeal…”
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13
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
Published in Nature (London) (17-07-2014)“…Malignancy is associated with altered expression of glycans and glycoproteins that contribute to the cellular glycocalyx. We constructed a glycoprotein…”
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The Effect of CYP2C19 Polymorphism on the Pharmacokinetics and Pharmacodynamics of Clopidogrel: A Possible Mechanism for Clopidogrel Resistance
Published in Clinical pharmacology and therapeutics (01-08-2008)“…We evaluated the effect of the CYP2C19 genotype on the pharmacokinetics and pharmacodynamcis of clopidogrel. Twenty‐four subjects were divided into three…”
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Oncogenic BRAF fusions in mucosal melanomas activate the MAPK pathway and are sensitive to MEK/PI3K inhibition or MEK/CDK4/6 inhibition
Published in Oncogene (08-06-2017)“…Despite remarkable progress in cutaneous melanoma genomic profiling, the mutational landscape of primary mucosal melanomas (PMM) remains unclear. Forty-six…”
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Polar Codes for Q-Ary Channels, q=2
Published in IEEE transactions on information theory (01-02-2013)“…We study polarization for nonbinary channels with input alphabet of size q =2 r , r =2,3,... Using Arıkan's polarizing kernel H 2 , we prove that the virtual…”
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On‐target sorafenib toxicity predicts improved survival in hepatocellular carcinoma: a multi‐centre, prospective study
Published in Alimentary pharmacology & therapeutics (01-04-2017)“…Summary Background Hepatocellular carcinoma (HCC) is the sixth most common cancer worldwide and has high mortality despite treatment. While sorafenib has a…”
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Multidecadal and multicentennial variability of the meridional overturning circulation
Published in Geophysical research letters (01-11-2008)“…The variability of the meridional overturning circulation (MOC) simulated in a multimillenial control integration of the Kiel Climate Model (KCM) displays…”
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Randomized phase II study of axitinib versus placebo plus best supportive care in second-line treatment of advanced hepatocellular carcinoma
Published in Annals of oncology (01-12-2015)“…The efficacy and safety of axitinib, a potent and selective vascular endothelial growth factor receptors 1–3 inhibitor, combined with best supportive care…”
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Correcting North Atlantic sea surface salinity biases in the Kiel Climate Model: influences on ocean circulation and Atlantic Multidecadal Variability
Published in Climate dynamics (01-10-2016)“…A long-standing problem in climate models is the large sea surface salinity (SSS) biases in the North Atlantic. In this study, we describe the influences of…”
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