Search Results - "PARK, Joobae"

Aberrant Methylation of APC, MGMT, RASSF2A, and Wif-1 Genes in Plasma as a Biomarker for Early Detection of Colorectal Cancer by Lee, Bo Bin, Lee, Eun Ju, Jung, Eun Hyun, Chun, Ho-Kyung, Chang, Dong Kyoung, Song, Sang Yong, Park, Joobae, Kim, Duk-Hwan

“…Purpose: To identify epigenetic molecular makers in plasma for the early detection of colorectal cancer. Experimental Design: We retrospectively analyzed the…”
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Synergistic Effect of Bcl-2 and Cyclin A2 on Adverse Recurrence-Free Survival in Stage I Non-small Cell Lung Cancer by Ko, Eunkyung, Kim, Yujin, Cho, Eun Yoon, Han, Jungho, Shim, Young Mog, Park, Joobae, Kim, Duk-Hwan

“…ABSTRACT Background The prognostic significance of cyclin A2 overexpression in non-small cell lung cancer (NSCLC) is controversial. Methods To understand the…”
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Copy Number Gains at 8q24 and 20q11-q13 in Gastric Cancer Are More Common in Intestinal-Type than Diffuse-Type by Jin, Dong-Hao, Park, Seong-Eun, Lee, Jeeyun, Kim, Kyung-Mi, Kim, Sung, Kim, Duk-Hwan, Park, Joobae

“…The present study was aimed at discovering DNA copy number alterations (CNAs) involved in the carcinogenesis of stomach and at understanding their…”
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Two genetic variants in telomerase-associated protein 1 are associated with stomach cancer risk by Jin, Dong-Hao, Kim, Sung, Kim, Duk-Hwan, Park, Joobae

“…This study examined the impact of two single-nucleotide polymorphisms (SNPs) in the telomerase-associated protein 1 (TEP1) gene on the risk of breast,…”
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Elevated mRNA levels of DNA methyltransferase‐1 as an independent prognostic factor in primary nonsmall cell lung cancer by Kim, Hojoong, Kwon, Young Mi, Kim, Jin Seuk, Han, Joungho, Shim, Young Mog, Park, Joobae, Kim, Duk‐Hwan

“…BACKGROUND. Despite many reports about the involvement of DNA methyltransferases (DNMTs) in human cancers, including nonsmall cell lung cancer (NSCLC), the…”
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Glutamate receptor‐mediated phosphorylation of ezrin/radixin/moesin proteins is implicated in filopodial protrusion of primary cultured hippocampal neuronal cells by Kim, Han‐Seop, Bae, Chang‐Dae, Park, Joobae

“…J. Neurochem. (2010) 113, 1565–1576. Previously, we reported the phosphorylation of moesin induced by electroconvulsive shock in rat brain and by glutamate in…”
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Chromatin CKAP2, a new proliferation marker, as independent prognostic indicator in breast cancer by Kim, Han-Seong, Koh, Jae-Soo, Choi, Yong-Bock, Ro, Jungsil, Kim, Hyun-Kyoung, Kim, Mi-Kyung, Nam, Byung-Ho, Kim, Kyung-Tae, Chandra, Vishal, Seol, Hye-Sil, Noh, Woo-Chul, Kim, Eun-Kyu, Park, Joobae, Bae, Chang-Dae, Hong, Kyeong-Man

“…The level of proliferation activity is a strong prognostic or predictive indicator in breast cancer, but its optimal measurement is still in debate,…”
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NGF-induced moesin phosphorylation is mediated by the PI3K, Rac1 and Akt and required for neurite formation in PC12 cells by Jeon, Songhee, Park, Jung-Keug, Bae, Chang-Dae, Park, Joobae

“…Moesin is a member of ERM family proteins which act as the cross-linkers between plasma membrane and actin-cytoskeleton and is activated by phosphorylation at…”
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Cohypermethylation of p16 and FHIT promoters as a prognostic factor of recurrence in surgically resected stage I non-small cell lung cancer by JIN SEUK KIM, JIN WOOK KIM, HAN, Joungho, YOUNG MOG SHIM, PARK, Joobae, KIM, Duk-Hwan

“…Despite advances in the detection and treatment of lung cancer, the prognosis for patients with lung cancer is poor, partly as a result of recurrences. We…”
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Tumor-Specific Methylation in Bronchial Lavage for the Early Detection of Non-Small-Cell Lung Cancer by Kim, Hojoong, Kwon, Young Mi, Kim, Jin Seuk, Lee, Haengbyoung, Park, Jung-Ho, Shim, Young Mog, Han, Joungho, Park, Joobae, Kim, Duk-Hwan

“…The aim of this study was to identify tumor-specific methylation in bronchial lavage for the early detection of non-small-cell lung cancer (NSCLC) by…”
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TMAP/CKAP2 is essential for proper chromosome segregation by Hong, Kyung Uk, Kim, Eunhee, Bae, Chang-Dae, Park, Joobae

“…Tumor-associated microtubule-associated protein (TMAP), also known as cytoskeleton associated protein 2 (CKAP2), is a novel mitotic spindle-associated protein…”
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Direct quantification of polo-like kinase 1 activity in cells and tissues using a highly sensitive and specific ELISA assay by Park, Jung-Eun, Li, Luowei, Park, Joobae, Knecht, Rainald, Strebhardt, Klaus, Yuspa, Stuart H, Lee, Kyung S

“…Polo-like kinase 1 (Plk1) plays a pivotal role in the regulation of cellular proliferation. Plk1 is overexpressed in [almost equal to]80% of human tumors of…”
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Promoter Hypermethylation of the p16 Gene Is Associated with Poor Prognosis in Recurrent Early-Stage Hepatocellular Carcinoma by KO, Eunkyung, KIM, Yujin, KIM, Sung-Joo, JOH, Jae-Won, SONG, Sangyong, PARK, Cheol-Keun, PARK, Joobae, KIM, Duk-Hwan

“…Despite significant advances in the detection and treatment of hepatocellular carcinoma, the prognosis of patients with hepatocellular carcinoma remains very…”
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Cdk1-Cyclin B1-mediated Phosphorylation of Tumor-associated Microtubule-associated Protein/Cytoskeleton-associated Protein 2 in Mitosis by Hong, Kyung Uk, Kim, Hyun-Jun, Kim, Hyo-Sil, Seong, Yeon-Sun, Hong, Kyeong-Man, Bae, Chang-Dae, Park, Joobae

“…During mitosis, establishment of structurally and functionally sound bipolar spindles is necessary for maintaining the fidelity of chromosome segregation…”
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Recapitulation of previous genome-wide association studies with two distinct pathophysiological entities of gastric cancer in the Korean population by Hwang, Joo-Yeon, Kim, Duk-Hwan, Ji, Yong-Ick, Jin Go, Min, Heo, Lyong, Jin Kim, Young, Sung Sohn, Tae, Hyung Noh, Jae, Kim, Sung, Lee, Yeon-Su, Kim, Sook-Young, Kim, Young-Woo, Won Ryu, Keun, Choi, Il Ju, Lee, Juyoung, Kim, Bong-Jo, Han, Bok-Ghee, Park, Joobae, Lee, Jong-Young

“…Gastric cancer (GC) is the most common malignancy. The incidence rates remain remarkably high in East Asians. Although genome-wide association studies in the…”
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Functional Importance of the Anaphase-Promoting Complex-Cdh1-Mediated Degradation of TMAP/CKAP2 in Regulation of Spindle Function and Cytokinesis by Hong, Kyung Uk, Park, Young Soo, Seong, Yeon-Sun, Kang, Dongmin, Bae, Chang-Dae, Park, Joobae

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Specific primary sequence requirements for Aurora B kinase-mediated phosphorylation and subcellular localization of TMAP during mitosis by Kim, Hyun-Jun, Kwon, Hye-Rim, Bae, Chang-Dae, Park, Joobae, Hong, Kyung U.

“…During mitosis, regulation of protein structures and functions by phosphorylation plays critical roles in orchestrating a series of complex events essential…”
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Downregulation of regenerating islet-derived 3 alpha (REG3A) in primary human gastric adenocarcinomas by Choi, Bongkun, Suh, Yousin, Kim, Woo-Ho, Christa, Laurence, Park, Joobae, Bae, Chang-Dae

“…Gastric carcinoma is considered to be one of the most prevalent cancers worldwide. We have performed differential-display polymerase chain reaction (DD-PCR) in…”
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Promoter Methylation of Retinoic Acid Receptor Beta 2 and the Development of Second Primary Lung Cancers in Non–Small-Cell Lung Cancer by JIN SEUK KIM, LEE, Haengbung, KIM, Hojoong, YOUNG MOG SHIM, HAN, Joungho, PARK, Joobae, KIM, Duk-Hwan

“…To investigate whether the promoter hypermethylation of retinoic acid receptor beta 2 (RARbeta2) is associated with the development of second primary lung…”
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RhoA and Rho Kinase-dependent Phosphorylation of Moesin at Thr-558 in Hippocampal Neuronal Cells by Glutamate by Jeon, Songhee, Kim, Sohee, Park, Jong-Bae, Suh, Pann-Ghill, Kim, Yong Sik, Bae, Chang-Dae, Park, Joobae

“…When we were studying phosphorylated proteins in the rat brain after electroconvulsive shock (ECS), we observed the rapid phosphorylation of a 75-kDa protein,…”
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