Search Results - "PARK, James O"

Targeting of Primary Breast Cancers and Metastases in a Transgenic Mouse Model Using Rationally Designed Multifunctional SPIONs by Kievit, Forrest M, Stephen, Zachary R, Veiseh, Omid, Arami, Hamed, Wang, Tingzhong, Lai, Vy P, Park, James O, Ellenbogen, Richard G, Disis, Mary L, Zhang, Miqin

“…Breast cancer remains one of the most prevalent and lethal malignancies in women. The inability to diagnose small volume metastases early has limited effective…”
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Chitosan–alginate 3D scaffolds as a mimic of the glioma tumor microenvironment by Kievit, Forrest M, Florczyk, Stephen J, Leung, Matthew C, Veiseh, Omid, Park, James O, Disis, Mary L, Zhang, Miqin

“…Abstract Despite recent advances in the understanding of its cell biology, glioma remains highly lethal. Development of effective therapies requires a…”
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Segmental Yttrium-90 Radioembolization versus Segmental Chemoembolization for Localized Hepatocellular Carcinoma: Results of a Single-Center, Retrospective, Propensity Score–Matched Study by Padia, Siddharth A., MD, Johnson, Guy E., MD, Horton, Kathryn J., MD, Ingraham, Christopher R., MD, Kogut, Matthew J., MD, Kwan, Sharon, MD, Vaidya, Sandeep, MD, Monsky, Wayne L., MD, PhD, Park, James O., MD, Bhattacharya, Renuka, MD, Hippe, Daniel S., MS, Harris, William P., MD

“…Abstract Purpose To compare segmental radioembolization with segmental chemoembolization for localized, unresectable hepatocellular carcinoma (HCC) not…”
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Preoperative Chemotherapy and the Risk of Hepatotoxicity and Morbidity after Liver Resection for Metastatic Colorectal Cancer: A Single Institution Experience by Wolf, Patrick S., MD, Park, James O., MD, Bao, Fei, MD, Allen, Peter J., MD, FACS, DeMatteo, Ronald P., MD, FACS, Fong, Yuman, MD, FACS, Jarnagin, William R., MD, FACS, Kingham, T. Peter, MD, Gönen, Mithat, PhD, Kemeny, Nancy, MD, Shia, Jinru, MD, D'Angelica, Michael I., MD, FACS

“…Background Patients undergoing liver resection for colorectal cancer liver metastasis (CRCLM) are often treated with chemotherapy before surgery. However, the…”
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Cell transcytosing poly-arginine coated magnetic nanovector for safe and effective siRNA delivery by Veiseh, Omid, Kievit, Forrest M, Mok, Hyejung, Ayesh, Joseph, Clark, Cassra, Fang, Chen, Leung, Matthew, Arami, Hamed, Park, James O, Zhang, Miqin

“…Abstract Lack of safe and effective carriers for delivery of RNA therapeutics remains a barrier to its broad clinical application. We report the development of…”
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Standardization of perioperative care facilitates safe discharge by postoperative day five after pancreaticoduodenectomy by Daniel, Sara K, Thornblade, Lucas W, Mann, Gary N, Park, James O, Pillarisetty, Venu G

“…Pancreaticoduodenectomy is a complex surgical procedure associated with high morbidity and prolonged length of stay. Enhanced recovery after surgery principles…”
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Glypican-3 targeted delivery of 89Zr and 90Y as a theranostic radionuclide platform for hepatocellular carcinoma by Labadie, Kevin P., Ludwig, Andrew D., Lehnert, Adrienne L., Hamlin, Donald K., Kenoyer, Aimee L., Sullivan, Kevin M., Daniel, Sara K., Mihailovic, Tara N., Sham, Jonathan G., Orozco, Johnnie J., Yeung, Raymond S., Chen, Delphine L., Wilbur, D. Scott, Miyaoka, Robert S., Park, James O.

“…Glypican-3 (GPC3) is a tumor associated antigen expressed by hepatocellular carcinoma (HCC) cells. This preclinical study evaluated the efficacy of a…”
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Chitosan-Alginate Scaffold Culture System for Hepatocellular Carcinoma Increases Malignancy and Drug Resistance by Leung, Matthew, Kievit, Forrest M, Florczyk, Stephen J, Veiseh, Omid, Wu, Jennifer, Park, James O, Zhang, Miqin

“…Purpose Hepatocellular carcinoma (HCC) is a prevalent solid malignancy. Critically needed discovery of new therapeutics has been hindered by lack of an in…”
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Pilot study of humanized glypican-3-targeted zirconium-89 immuno-positron emission tomography for hepatocellular carcinoma by Dickerson, Lindsay K., Lehnert, Adrienne L., Hamlin, Donald K., Labadie, Kevin P., Goodsell, Kristin E., Liu, Yongjun, Li, Yawen, Wilbur, D. Scott, Miyaoka, Robert, Park, James O.

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Comparative Effectiveness of Minimally Invasive Surgery and Conventional Approaches to Major or Challenging Hepatectomy by Thornblade, Lucas W., MD, Shi, Xu, MS, Ruiz, Alex, BS, Flum, David R., MD, MPH, FACS, Park, James O., MD, FACS

“…Abstract Background The benefits of minimally invasive surgery (MIS) for low-risk or minor liver resection are well established. There is growing interest in…”
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Glypican-3 targeted positron emission tomography detects sub-centimeter tumors in a xenograft model of hepatocellular carcinoma by Labadie, Kevin P., Lehnert, Adrienne L., Kenoyer, Aimee L., Hamlin, Donald K., Ludwig, Andrew D., Utria, Alan F., Daniel, Sara K., Mihailovic, Tara N., Prossnitz, Alexander, Orozco, Johnnie J., Li, Yawen, Wilbur, D. Scott, Miyaoka, Robert S., Park, James O.

“…Background Early intrahepatic recurrence is common after surgical resection of hepatocellular carcinoma (HCC) and leads to increased morbidity and mortality…”
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Toward consensus reporting of radiation-induced liver toxicity in the treatment of primary liver malignancies: Defining clinically relevant endpoints by Chapman, Tobias R., Bowen, Stephen R., Schaub, Stephanie K., Yeung, Rosanna H., Kwan, Sharon W., Park, James O., Yu, Lei, Harris, William P., Johnson, Guy E., Liou, Iris W., Nyflot, Matthew J., Apisarnthanarax, Smith

“…Our purpose was to define the most clinically relevant “nonclassic” radiation-induced liver disease (RILD) endpoints in cirrhotic patients receiving…”
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Trends in the Utilization and Impact of Radiofrequency Ablation for Hepatocellular Carcinoma by Massarweh, Nader N., MD, Park, James O., MD, Farjah, Farhood, MD, MPH, Yeung, Raymond S.W., MD, FACS, Symons, Rebecca Gaston, MPH, Vaughan, Thomas L., MD, MPH, FACS, Baldwin, Laura-Mae, MD, MPH, Flum, David R., MD, MPH, FACS

“…Background The incidence of hepatocellular carcinoma (HCC) is rising and radiofrequency ablation (RFA) appears to be increasingly used. The nationwide use and…”
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Glypican-3 Targeting of Liver Cancer Cells Using Multifunctional Nanoparticles by Park, James O., Stephen, Zachary, Sun, Conroy, Veiseh, Omid, Kievit, Forrest M., Fang, Chen, Leung, Matthew, Mok, Hyejung, Zhang, Miqin

“…Imaging is essential in accurately detecting, staging, and treating primary liver cancer (hepatocellular carcinoma [HCC]), one of the most prevalent and lethal…”
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Mobilization of CD8 + T Cells via CXCR4 Blockade Facilitates PD-1 Checkpoint Therapy in Human Pancreatic Cancer by Seo, Yongwoo David, Jiang, Xiuyun, Sullivan, Kevin M, Jalikis, Florencia G, Smythe, Kimberly S, Abbasi, Arezou, Vignali, Marissa, Park, James O, Daniel, Sara K, Pollack, Seth M, Kim, Teresa S, Yeung, Raymond, Crispe, Ian Nicholas, Pierce, Robert H, Robins, Harlan, Pillarisetty, Venu G

“…Pancreatic ductal adenocarcinoma (PDA) is rarely cured, and single-agent immune checkpoint inhibition has not demonstrated clinical benefit despite the…”
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Blockade of interleukin 10 potentiates antitumour immune function in human colorectal cancer liver metastases by Sullivan, Kevin M, Jiang, Xiuyun, Guha, Prajna, Lausted, Christopher, Carter, Jason A, Hsu, Cynthia, Labadie, Kevin P, Kohli, Karan, Kenerson, Heidi L, Daniel, Sara K, Yan, Xiaowei, Meng, Changting, Abbasi, Arezou, Chan, Marina, Seo, Y David, Park, James O, Crispe, Ian Nicholas, Yeung, Raymond S, Kim, Teresa S, Gujral, Taranjit S, Tian, Qiang, Katz, Steven C, Pillarisetty, Venu G

“…Programmed cell death protein 1 (PD-1) checkpoint inhibition and adoptive cellular therapy have had limited success in patients with microsatellite stable…”
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Methacrylated Bovine Serum Albumin and Tannic Acid Composite Materials for Three-Dimensional Printing Tough and Mechanically Functional Parts by Smith, Patrick T., Altin, Gokce, Millik, S. Cem, Narupai, Benjaporn, Sietz, Cameron, Park, James O., Nelson, Alshakim

“…Nature uses proteins as building blocks to create three-dimensional (3D) structural components (like spiderwebs and tissue) that are recycled within a closed…”
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Additive Manufacturing of Engineered Living Materials with Bio‐Augmented Mechanical Properties and Resistance to Degradation by Altin‐Yavuzarslan, Gokce, Brooks, Sierra M., Yuan, Shuo‐Fu, Park, James O., Alper, Hal S., Nelson, Alshakim

“…Engineered living materials (ELMs) combine living cells with polymeric matrices to yield unique materials with programmable functions. While the cellular…”
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A phase II trial of lanreotide for the prevention of postoperative pancreatic fistula by Pillarisetty, Venu G., Abbasi, Arezou, Park, James O., Sham, Jonathan G.

“…Clinically relevant postoperative pancreatic fistula (CR-POPF) is a significant contributor to morbidity after pancreatectomy. Somatostatin analogues have…”
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Propensity Score-Matched Analysis Comparing Robotic and Laparoscopic Right and Extended Right Hepatectomy by Chong, Charing C, Fuks, David, Lee, Kit-Fai, Zhao, Joseph J, Choi, Gi Hong, Sucandy, Iswanto, Chiow, Adrian K H, Marino, Marco V, Gastaca, Mikel, Wang, Xiaoying, Lee, Jae Hoon, Efanov, Mikhail, Kingham, T Peter, D'Hondt, Mathieu, Troisi, Roberto I, Choi, Sung-Hoon, Sutcliffe, Robert P, Chan, Chung-Yip, Lai, Eric C H, Park, James O, Di Benedetto, Fabrizio, Rotellar, Fernando, Sugioka, Atsushi, Coelho, Fabricio Ferreira, Ferrero, Alessandro, Long, Tran Cong Duy, Lim, Chetana, Scatton, Olivier, Liu, Qu, Schmelzle, Moritz, Pratschke, Johann, Cheung, Tan-To, Liu, Rong, Han, Ho-Seong, Tang, Chung Ngai, Goh, Brian K P

“…Laparoscopic and robotic techniques have both been well adopted as safe options in selected patients undergoing hepatectomy. However, it is unknown whether…”
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