Search Results - "PARHAM, KATE A."

Autoreactive, Low-Affinity T Cells Preferentially Drive Differentiation of Short-Lived Memory B Cells at the Expense of Germinal Center Maintenance by Jain, Rajiv W., Parham, Kate A., Tesfagiorgis, Yodit, Craig, Heather C., Romanchik, Emiliano, Kerfoot, Steven M.

“…B cell fate decisions within a germinal center (GC) are critical to determining the outcome of the immune response to a given antigen. Here, we characterize GC…”
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Monovalent and trivalent VSV-based COVID-19 vaccines elicit neutralizing antibodies and CD8+ T cells against SARS-CoV-2 variants by Parham, Kate A., Kim, Gyoung Nyoun, Richer, Connor G., Ninkov, Marina, Wu, Kunyu, Saeedian, Nasrin, Li, Yue, Rashu, Rasheduzzaman, Barr, Stephen D., Arts, Eric J., Haeryfar, S.M. Mansour, Kang, C. Yong, Troyer, Ryan M.

“…Recombinant vesicular stomatitis virus (rVSV) vaccines expressing spike proteins of Wuhan, Beta, and/or Delta variants of SARS-CoV-2 were generated and tested…”
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Interleukin-3 greatly expands non-adherent endothelial forming cells with pro-angiogenic properties by Moldenhauer, Lachlan M., Cockshell, Michaelia P., Frost, Lachlan, Parham, Kate A., Tvorogov, Denis, Tan, Lih Y., Ebert, Lisa M., Tooley, Katie, Worthley, Stephen, Lopez, Angel F., Bonder, Claudine S.

“…Circulating endothelial progenitor cells (EPCs) provide revascularisation for cardiovascular disease and the expansion of these cells opens up the possibility…”
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Systemic administration of anti-CD20 indirectly reduces B cells in the inflamed meninges in a chronic model of central nervous system autoimmunity by Tesfagiorgis, Yodit, Kemal, Eden A., Craig, Heather C., Parham, Kate A., Kerfoot, Steven M.

“…Anti-CD20 B cell depleting therapies have demonstrated that B cells are important drivers of disease progress in Multiple Sclerosis, although the pathogenic…”
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Pre–Germinal Center Interactions with T Cells Are Natural Checkpoints to Limit Autoimmune B Cell Responses by Parham, Kate A., Tan, Xiu Xia Sherry, Morelli, Daniel M., Chowdhury, Lika, Craig, Heather C., Kerfoot, Steven M.

“…Interactions with Ag-specific T cells drive B cell activation and fate choices that ultimately determine the quality of high-affinity Ab responses. As such,…”
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Sphingosine 1‐phosphate is a ligand for peroxisome proliferator‐activated receptor‐γ that regulates neoangiogenesis by Parham, Kate A., Zebol, Julia R., Tooley, Katie L., Sun, Wai Y., Moldenhauer, Lachlan M., Cockshell, Michaelia P., Gliddon, Briony L., Moretti, Paul A., Tigyi, Gabor, Pitson, Stuart M., Bonder, Claudine S.

“…ABSTRACT Sphingosine 1‐phosphate (S1P) is a bio‐active lipid that can function both extracellularly and intracellularly to mediate a variety of cellular…”
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Fecal microbiota transplantation is safe and tolerable in patients with multiple sclerosis: A pilot randomized controlled trial by Al, Kait F., Craven, Laura J, Gibbons, Shaeley, Parvathy, Seema Nair, Wing, Ana Christina, Graf, Chantelle, Parham, Kate A, Kerfoot, Steven M, Wilcox, Hannah, Burton, Jeremy P, Kremenchutzky, Marcelo, Morrow, Sarah A, Casserly, Courtney, Meddings, Jon, Sharma, Manas, Silverman, Michael S.

“…Background Patients with MS have an altered gut microbiota compared to healthy individuals, as well as elevated small intestinal permeability, which may be…”
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A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis by Ebert, Lisa M., Tan, Lih Y., Johan, M. Zahied, Min, Kay Khine Myo, Cockshell, Michaelia P., Parham, Kate A., Betterman, Kelly L., Szeto, Paceman, Boyle, Samantha, Silva, Lokugan, Peng, Angela, Zhang, YouFang, Ruszkiewicz, Andrew, Zannettino, Andrew C. W., Gronthos, Stan, Koblar, Simon, Harvey, Natasha L., Lopez, Angel F., Shackleton, Mark, Bonder, Claudine S.

“…Desmogleins (DSG) are a family of cadherin adhesion proteins that were first identified in desmosomes and provide cardiomyocytes and epithelial cells with the…”
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Local Sphingosine Kinase 1 Activity Improves Islet Transplantation by Rojas-Canales, Darling, Penko, Daniella, Myo Min, Kay K, Parham, Kate A, Peiris, Heshan, Haberberger, Rainer V, Pitson, Stuart M, Drogemuller, Chris, Keating, Damien J, Grey, Shane T, Coates, Patrick T, Bonder, Claudine S, Jessup, Claire F

“…Pancreatic islet transplantation is a promising clinical treatment for type 1 diabetes, but success is limited by extensive β-cell death in the immediate…”
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Over-Expression of Sphingosine Kinase-1 Enhances a Progenitor Phenotype in Human Endothelial Cells by BARRETT, JEFFREY M., PARHAM, KATE A., PIPPAL, JYOTSNA B., COCKSHELL, MICHAELIA P., MORETTI, PAUL A. B., BRICE, SARAH L., PITSON, STUART M., BONDER, CLAUDINE S.

“…Please cite this paper as: Barrett, Parham, Pippal, Cockshell, Moretti, Brice, Pitson, and Bonder (2011). Over‐Expression of Sphingosine Kinase‐1 Enhances a…”
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Systemic administration of anti-CD20 indirectly reduces B cells in the inflamed meninges in a chronic model of central nervous system autoimmunity by Kerfoot, Steven, Tesfagiorgis, Yodit, Kemal, Eden A, Craig, Heather C, Parham, Kate A

“…Anti-CD20 B cell depleting therapies have demonstrated that B cells are important drivers of disease progress in Multiple Sclerosis, although the pathogenic…”
Get full text