Search Results - "PAPAZAFIRI, Panagiota"
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1
Knockdown of Amyloid Precursor Protein Increases Ion Channel Expression and Alters Ca2+ Signaling Pathways
Published in International journal of molecular sciences (24-01-2023)“…Although the physiological role of the full-length Amyloid Precursor Protein (APP) and its proteolytic fragments remains unclear, they are definitively crucial…”
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2
Enhanced Ca2+ Entry Sustains the Activation of Akt in Glucose Deprived SH-SY5Y Cells
Published in International journal of molecular sciences (26-01-2022)“…The two crucial cellular insults that take place during cerebral ischemia are the loss of oxygen and loss of glucose, which can both activate a cascade of…”
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3
The Epigenetic Controller Lysine-Specific Demethylase 1 (LSD1) Regulates the Outcome of Hepatitis C Viral Infection
Published in Cells (Basel, Switzerland) (01-11-2023)“…Hepatitis C virus (HCV) alters gene expression epigenetically to rearrange the cellular microenvironment in a beneficial way for its life cycle. The host…”
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4
Anti-apoptotic effects of allopregnanolone on P19 neurons
Published in The European journal of neuroscience (01-01-2006)“…Progesterone and its metabolites are potent allosteric modulators of GABAA receptor function, through a direct, non‐genomic interaction with specific receptor…”
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5
5,7,8-Trimethyl-benzopyran and 5,7,8-Trimethyl-1,4-benzoxazine Aminoamide Derivatives as Novel Antiarrhythmics against Ischemia−Reperfusion Injury
Published in Journal of medicinal chemistry (23-04-2009)“…6-Hydroxy-5,7,8-trimethyl-benzopyran derivatives and 5,7,8-trimethyl-1,4-benzoxazine analogues substituted by the lidocaine pharmacophore aminoamide…”
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6
Neurosteroids Alter p-ERK Levels and Tau Distribution, Restraining the Effects of High Extracellular Calcium
Published in International journal of molecular sciences (01-11-2024)“…Neurosteroids are undeniably regarded as neuroprotective mediators, regulating brain function by rapid non-genomic actions involving interference with…”
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7
Differential effects of calcium on PI3K-Akt and HIF-1α survival pathways
Published in Cell biology and toxicology (01-10-2016)“…Calcium signaling participates in the regulation of numberless cellular functions including cell cycle progression and cellular migration, important processes…”
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8
Neuronal microRNAs safeguard ER Ca2+ homeostasis and attenuate the unfolded protein response upon stress
Published in Cellular and molecular life sciences : CMLS (01-07-2022)“…Ca 2+ is a critical mediator of neurotransmitter release, synaptic plasticity, and gene expression, but also excitotoxicity. Ca 2+ signaling and homeostasis…”
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9
Deregulation of calcium homeostasis mediates secreted α–synuclein-induced neurotoxicity
Published in Neurobiology of aging (01-12-2013)“…Abstract α-Synuclein (AS) plays a crucial role in Parkinson's disease pathogenesis. AS is normally secreted from neuronal cells and can thus exert paracrine…”
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10
Comparative assessment of HIF-1α and Akt responses in human lung and skin cells exposed to benzo[α]pyrene: Effect of conditioned medium from pre-exposed primary fibroblasts
Published in Environmental toxicology (01-09-2016)“…ABSTRACT Exposure to atmospheric pollutants has been accused for many adverse health effects. Benzo[α]pyrene (Β[α]Ρ) in particular, the most extensively…”
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11
Vagiallene, a Rearranged C 15 Acetogenin from Laurencia obtusa
Published in Organic letters (03-05-2019)“…Vagiallene (1), a rearranged C acetogenin with a molecular formula and a carbon skeleton unprecedented in natural products, was isolated as a trace constituent…”
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12
Comparative assessment of HIF-1[alpha] and Akt responses in human lung and skin cells exposed to benzo[[alpha]]pyrene: Effect of conditioned medium from pre-exposed primary fibroblasts
Published in Environmental toxicology (01-09-2016)“…Exposure to atmospheric pollutants has been accused for many adverse health effects. Benzo[[alpha]]pyrene ([Beta][[alpha]]Ρ) in particular, the most…”
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13
Vagiallene, a Rearranged C15 Acetogenin from Laurencia obtusa
Published in Organic letters (03-05-2019)“…Vagiallene (1), a rearranged C15 acetogenin with a molecular formula and a carbon skeleton unprecedented in natural products, was isolated as a trace…”
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14
3D-QSAR using pharmacophore-based alignment and virtual screening for discovery of novel MCF-7 cell line inhibitors
Published in European journal of medicinal chemistry (01-09-2013)“…The development of a novel approach for the prediction of antiestrogenic activity is described, bringing up to date a previous pharmacophore study. Software…”
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15
Knockdown of Amyloid Precursor Protein Increases Ion Channel Expression and Alters Ca 2+ Signaling Pathways
Published in International journal of molecular sciences (24-01-2023)“…Although the physiological role of the full-length Amyloid Precursor Protein (APP) and its proteolytic fragments remains unclear, they are definitively crucial…”
Get full text
Journal Article -
16
Comparative assessment of HIF-1α and Akt responses in human lung and skin cells exposed to benzo[α]pyrene: Effect of conditioned medium from pre-exposed primary fibroblasts: COMPARATIVE ASSESSMENT OF B[α]P EFFECTS ON LUNG AND SKIN CELLS
Published in Environmental toxicology (01-09-2016)Get full text
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17
Dactylomelane Diterpenes from the Sea Hare Aplysia depilans
Published in Journal of natural products (Washington, D.C.) (27-03-2015)“…A chemical investigation of the organic extract of the sea hare Aplysia depilans, collected off Skyros Island, Greece, yielded eight new brominated diterpenes…”
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18
Neuronal microRNAs modulate TREK two-pore domain K+ channel expression and current density
Published in RNA biology (03-05-2020)“…The TREK family of leak potassium channels has been found to play critical roles in nociception, sensitivity to general anaesthetics, neuroprotection, and…”
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19
Computational modeling as part of alternative testing strategies in the respiratory and cardiovascular systems: Inhaled nanoparticle dose modeling based on representative aerosol measurements and corresponding toxicological analysis
Published in Nanotoxicology (01-05-2015)“…Abstract The objectives of modeling in this work were (a) the integration of two existing numerical models in order to connect external exposure to…”
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20
A glucose-based molecular rotor inhibitor of glycogen phosphorylase as a probe of cellular enzymatic function
Published in Organic & biomolecular chemistry (23-03-2022)“…Molecular rotors belong to a family of fluorescent compounds characterized as molecular switches, where a fluorescence on/off signal signifies a change in the…”
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