Emergently planned exclusive hub-and-spoke system in the epicenter of the first wave of COVID-19 pandemic in Italy: the experience of the largest COVID-19-free ICU hub for time-dependent diseases

BACKGROUNDLombardy was the epicenter in Italy of the first wave of COVID-19 pandemic. To face the contagion growth, from March 8 to May 8, 2020, a regional law redesigned the hub-and-spoke system for time-dependent diseases to better allocate resources for COVID-19 patients. METHODSWe report the reo...

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Published in:	Minerva anestesiologica Vol. 87; no. 10; pp. 1091 - 1099
Main Authors:	CHIEREGATO, Arturo, VERONESE, Giacomo, CURTO, Francesco, ZANIBONI, Matteo, FOSSI, Francesca, ZUMBO, Fabrizio, SCATTOLINI, Carla, COMPAGNONE, Christian, ALBERTI, Beatrice M., BACIU, Camelia, BERGESIO, Lavinia, CARENINI, Stefano M., CHEVALLARD, Giorgio, CIPOLLA, Cristiana, FORMENTANO, Alessandra C., GUIDI, Alessandro, MASSIMO, Francesco, GALLUCCIO, Irene, PAGANI, Silvano, PAPARONE, Rosaria, POZZI, Federico, PRESSATO, Lorenzo, PUGNETTI, Enrica, RIGANTI, Mauro, RUGGIERI, Francesco, TAGLIAFERRI, Fernanda, TRINCHERO, Gabriele, VASSENA, Emanuele, BASSI, Gabriele, GIUDICI, Riccardo, SACCHI, Marco, CHIARA, Osvaldo, AGOSTONI, Elio C., GRASSELLI, Giacomo, FUMAGALLI, Roberto
Format:	Journal Article
Language:	English
Published:	01-10-2021
Online Access:	Get full text
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Summary:	BACKGROUNDLombardy was the epicenter in Italy of the first wave of COVID-19 pandemic. To face the contagion growth, from March 8 to May 8, 2020, a regional law redesigned the hub-and-spoke system for time-dependent diseases to better allocate resources for COVID-19 patients. METHODSWe report the reorganization of the major hospital in Lombardy during COVID-19 pandemic, including the rearrangement of its ICU beds to face COVID-19 pandemic and fulfill its role as extended hub for time-dependent diseases while preserving transplant activity. To highlight the impact of the emergently planned hub-and-spoke system, all patients admitted to a COVID-19-free ICU hub for trauma, neurosurgical emergencies and stroke during the two-month period were retrospectively collected and compared to 2019 cohort. Regional data on organ procurement was retrieved. Observed-to-expected (OE) in-ICU mortality ratios were computed to test the impact of the pandemic on patients affected by time-dependent diseases. RESULTSDynamic changes in ICU resource allocation occurred according to local COVID-19 epidemiology/trends of patients referred for time-dependent diseases. The absolute increase of admissions for trauma, neurosurgical emergencies and stroke was roughly two-fold. Patients referred to the hub were older and characterized by more severe conditions. An increase in crude mortality was observed, though OE ratios for in-ICU mortality were not statistically different when comparing 2020 vs. 2019. An increase in local organ procurement was observed, limiting the debacle of regional transplant activity. CONCLUSIONSWe described the effects of a regional emergently planned hub-and-spoke system for time-dependent diseases settled in the epicenter of COVID-19 pandemic in Italy.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0375-9393 1827-1596
DOI:	10.23736/S0375-9393.21.15455-0