Search Results - "PAO, Camila R"
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1
Nebulized Lidocaine Prevents Airway Inflammation, Peribronchial Fibrosis, and Mucus Production in a Murine Model of Asthma
Published in Anesthesiology (Philadelphia) (01-09-2012)“…Evidence suggests that nebulized lidocaine is beneficial in asthma therapy, but to what extent and the mechanisms underlying this effect remain poorly…”
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2
Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19
Published in Blood (10-09-2020)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an emergent pathogen responsible for the coronavirus disease 2019 (COVID-19). Since its…”
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3
SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes
Published in Cell death discovery (01-03-2021)“…Infection by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been associated with leukopenia and uncontrolled inflammatory response in…”
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4
Endogenous PGD2 acting on DP2 receptor counter regulates Schistosoma mansoni infection-driven hepatic granulomatous fibrosis
Published in PLoS pathogens (01-08-2024)“…Identifying new molecular therapies targeted at the severe hepatic fibrosis associated with the granulomatous immune response to Schistosoma mansoni infection…”
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5
VIP plasma levels associate with survival in severe COVID‐19 patients, correlating with protective effects in SARS‐CoV‐2‐infected cells
Published in Journal of leukocyte biology (01-05-2022)“…Infection by SARS‐CoV‐2 may elicit uncontrolled and damaging inflammatory responses. Thus, it is critical to identify compounds able to inhibit virus…”
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6
Repeated Allergen Exposure in A/J Mice Causes Steroid-Insensitive Asthma via a Defect in Glucocorticoid Receptor Bioavailability
Published in The Journal of immunology (1950) (01-08-2018)“…The importance of developing new animal models to assess the pathogenesis of glucocorticoid (GC)-insensitive asthma has been stressed. Because of the…”
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7
Eosinophils increase macrophage ability to control intracellular Leishmania amazonensis infection via PGD2 paracrine activity in vitro
Published in Cellular immunology (01-05-2021)“…•Eosinophils enhance macrophage ability to control intracellular L. amazonensis infection in vitro.•Eosinophil-driven mechanism depends on a paracrine activity…”
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8
Simvastatin Downregulates the SARS-CoV-2-Induced Inflammatory Response and Impairs Viral Infection Through Disruption of Lipid Rafts
Published in Frontiers in immunology (18-02-2022)“…Coronavirus disease 2019 (COVID-19) is currently a worldwide emergency caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). In observational…”
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9
JM25-1, a Lidocaine Analog Combining Airway Relaxant and Antiinflammatory Properties: Implications for New Bronchospasm Therapy
Published in Anesthesiology (Philadelphia) (01-01-2016)“…BACKGROUND:Inhaled lidocaine antagonized bronchospasm in animal models and patients, but adverse effects limited its efficacy. This study evaluated the…”
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10
Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators
Published in PLoS pathogens (16-12-2020)“…Viruses are obligate intracellular parasites that make use of the host metabolic machineries to meet their biosynthetic needs. Thus, identifying the host…”
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11
Correction: SARS-CoV-2 engages inflammasome and pyroptosis in human primary monocytes
Published in Cell death discovery (19-05-2021)Get full text
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12
In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19
Published in Journal of antimicrobial chemotherapy (18-06-2021)“…Abstract Background Current approaches of drug repurposing against COVID-19 have not proven overwhelmingly successful and the SARS-CoV-2 pandemic continues to…”
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13
Endogenous PGD.sub.2 acting on DP2 receptor counter regulates Schistosoma mansoni infection-driven hepatic granulomatous fibrosis
Published in PLoS pathogens (22-08-2024)“…Identifying new molecular therapies targeted at the severe hepatic fibrosis associated with the granulomatous immune response to Schistosoma mansoni infection…”
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14
Eosinophils increase macrophage ability to control intracellular Leishmania amazonensis infection via PGD 2 paracrine activity in vitro
Published in Cellular immunology (01-05-2021)“…Clinical and experimental studies have described eosinophil infiltration in Leishmania amazonensis infection sites, positioning eosinophils strategically…”
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15
JM25-1, a Lidocaine Analog Combining Airway Relaxant and Antiinflammatory Properties
Published in Anesthesiology (Philadelphia) (01-01-2016)“…Abstract Background Inhaled lidocaine antagonized bronchospasm in animal models and patients, but adverse effects limited its efficacy. This study evaluated…”
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