Search Results - "PANTOS, Constantinos"

Use of triiodothyronine to treat critically ill COVID-19 patients: a new clinical trial by Pantos, Constantinos, Tseti, Ioulia, Mourouzis, Iordanis

“…[...]inotropes and vasoactive agents, often used in ICU treatments, can increase tissue injury and viral load via p38 MAPK activation [1, 2]. [...]a vicious…”
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Donor Heart Preservation: Current Knowledge and the New Era of Machine Perfusion by Kounatidis, Dimitris, Brozou, Vassiliki, Anagnostopoulos, Dimitris, Pantos, Constantinos, Lourbopoulos, Athanasios, Mourouzis, Iordanis

“…Heart transplantation remains the conventional treatment in end-stage heart failure, with static cold storage (SCS) being the standard technique used for donor…”
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Effects of Acute Triiodothyronine Treatment in Patients with Anterior Myocardial Infarction Undergoing Primary Angioplasty: Evidence from a Pilot Randomized Clinical Trial (ThyRepair Study) by Pantos, Constantinos I, Trikas, Athanasios G, Pissimisis, Evangelos G, Grigoriou, Konstantinos P, Stougiannos, Pavlos N, Dimopoulos, Antonios K, Linardakis, Sarantos I, Alexopoulos, Nikolaos A, Evdoridis, Costas G, Gavrielatos, Gerasimos D, Patsourakos, Nikolaos G, Papakonstantinou, Nikolaos D, Theodosis-Georgilas, Anastasios D, Mourouzis, Iordanis S

“…Thyroid hormone has a differential action on healthy and ischemic heart. Triiodothyronine (T3) administration improved postischemic cardiac function while it…”
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Translational Block in Stroke: A Constructive and “Out-of-the-Box” Reappraisal by Lourbopoulos, Athanasios, Mourouzis, Iordanis, Xinaris, Christodoulos, Zerva, Nefeli, Filippakis, Konstantinos, Pavlopoulos, Angelos, Pantos, Constantinos

“…Why can we still not translate preclinical research to clinical treatments for acute strokes? Despite > 1000 successful preclinical studies, drugs, and…”
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Triiodothyronine for the treatment of critically ill patients with COVID-19 infection: A structured summary of a study protocol for a randomised controlled trial by Pantos, Constantinos, Kostopanagiotou, Georgia, Armaganidis, Apostolos, Trikas, Athanasios, Tseti, Ioulia, Mourouzis, Iordanis

“…Tissue hypoxia is the main cause of multi-organ dysfunction in sepsis. However, effective pharmacological treatments to combat sepsis-induced tissue hypoxia…”
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The Emerging Role of TR α 1 in Cardiac Repair: Potential Therapeutic Implications by Constantinos, Pantos, Mourouzis, Iordanis

“…Thyroid hormone (TH) is critical for adapting living organisms to environmental stress. Plasma circulating tri-iodothyronine (T3) levels drop in most disease…”
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Translating thyroid hormone into clinical practice: lessons learned from the post-hoc analysis on data available from the ThyRepair study by Pantos, Constantinos I, Grigoriou, Konstantinos P, Trikas, Athanasios G, Alexopoulos, Nikolaos A, Mourouzis, Iordanis S

“…Thyroid hormone (TH) appears to have a reparative action on the postinfarcted myocardium. This novel action was recently tested in a pilot, randomized,…”
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Thyroid hormone receptor α1 as a novel therapeutic target for tissue repair by Pantos, Constantinos, Mourouzis, Iordanis

“…Analogies between the damaged tissue and developing organ indicate that a regulatory network that drives embryonic organ development may control aspects of…”
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The Use of L-Glucose in Cancer Diagnosis: Results from In Vitro and In Vivo Studies by Anastasiou, Ioanna A, Eleftheriadou, Ioanna, Tentolouris, Anastasios, Mourouzis, Iordanis, Pantos, Constantinos, Tentolouris, Nikolaos

“…Cancer cells are characterized by metabolic heterogeneity. Although many research groups make efforts to analyze this heterogeneity, little attention has been…”
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Ectopic bone formation and systemic bone loss in a transmembrane TNF-driven model of human spondyloarthritis by Christodoulou-Vafeiadou, Eleni, Geka, Christina, Ntari, Lydia, Kranidioti, Ksanthi, Argyropoulou, Eleni, Meier, Florian, Armaka, Marietta, Mourouzis, Iordanis, Pantos, Constantinos, Rouchota, Maritina, Loudos, George, Denis, Maria C, Karagianni, Niki, Kollias, George

“…Background The transmembrane-TNF transgenic mouse, TgA86, has been shown to develop spontaneously peripheral arthritis with signs of axial involvement. To…”
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Principal Aspects Regarding the Maintenance of Mammalian Mitochondrial Genome Integrity by Vasileiou, Panagiotis V S, Mourouzis, Iordanis, Pantos, Constantinos

“…Mitochondria have emerged as key players regarding cellular homeostasis not only due to their contribution regarding energy production through oxidative…”
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L-Thyroxine induces thermotolerance in yeast by Papamichael, Konstantinos, Delitheos, Basil, Mourouzis, Iordanis, Pantos, Constantinos, Tiligada, Ekaterini

“…The cellular stress response (CSR) is a universal inducible reaction modulated, among others, by heat, drugs, and hormones. We aimed to investigate the role of…”
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Protein kinase C and cardiac dysfunction: a review by Singh, Raphael M., Cummings, Emanuel, Pantos, Constantinos, Singh, Jaipaul

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Theophrastus Bombastus Von Hohenheim: Theological Reformer, Philosopher and Physician by Michaleas, Spyros N., Pantos, Constantinos, Chatzipanagiotou, Stylianos, Samonis, George, Karamanou, Marianna

“…Theophrastus Bombastus Von Hohenheim (1493–1541), known as Paracelsus, was a German-Swiss Renaissance man. His interests included alchemy and medicine. During…”
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Cardiovascular Risk of Synthetic, Non-Biologic Disease-Modifying Anti- Rheumatic Drugs (DMARDs) by Mourouzis, Iordanis S, Manolis, Antonis S, Pantos, Constantinos

“…Patients with rheumatoid diseases have an increased risk of cardiovascular disease (CVD) and CVD-related death compared with the general population. Both the…”
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Thyroid hormone and recovery of cardiac function in patients with acute myocardial infarction: a strong association? by Lymvaios, Ioannis, Mourouzis, Iordanis, Cokkinos, Dennis V, Dimopoulos, Meletios A, Toumanidis, Savvas T, Pantos, Constantinos

“…ObjectiveThis study investigated whether changes in thyroid hormone (TH) in plasma are associated with the recovery of cardiac function in patients with acute…”
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Effects of Thyroid Hormone on Tissue Hypoxia: Relevance to Sepsis Therapy by Lourbopoulos, Athanasios I, Mourouzis, Iordanis S, Trikas, Athanasios G, Tseti, Ioulia K, Pantos, Constantinos I

“…Tissue hypoxia occurs in various conditions such as myocardial or brain ischemia and infarction, sepsis, and trauma, and induces cellular damage and tissue…”
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Thyroid Hormone and Tissue Repair: New Tricks for an Old Hormone? by Mourouzis, Iordanis, Constantinos, Pantos, Politi, Efstathia

“…Although the role of thyroid hormone during embryonic development has long been recognized, its role later in adult life remains largely unknown. However,…”
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Assessment of frailty and related outcomes in older patients with heart failure: A cohort study by Tournas, Georgios, Kourek, Christos, Mantzaraki, Vassiliki, Georgiopoulos, Georgios, Pantos, Constantinos, Toumanidis, Savvas, Briasoulis, Alexandros, Paraskevaidis, Ioannis

“…Heart failure (HF) is a common cause of morbidity and mortality in older patients. Frailty is prevalent and complicates the course of HF. We sought to…”
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Endothelin Modulates Rhythm Disturbances and Autonomic Responses to Acute Emotional Stress in Rats by Mouchtouri, Eleni-Taxiarchia, Konstantinou, Thomas, Lekkas, Panagiotis, Lianopoulou, Alexandra, Kotsaridou, Zoi, Mourouzis, Iordanis, Pantos, Constantinos, Kolettis, Theofilos M

“…The ubiquitous peptide endothelin is currently under investigation as a modulatory factor of autonomic responses to acute emotional stress. Baseline plasma…”
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