Search Results - "PANKEWYCZ, O. G"

Prognostic Utility of Hypothermic Machine Perfusion in Deceased Donor Renal Transplantation by Patel, S.K, Pankewycz, O.G, Nader, N.D, Zachariah, M, Kohli, R, Laftavi, M.R

“…Abstract Pulsatile pump perfusion of kidney transplants is known to decrease delayed graft function (DGF) and improve 1 year graft survival when compared to…”
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Effect of Increased Pressure During Pulsatile Pump Perfusion of Deceased Donor Kidneys in Transplantation by Patel, S.K, Pankewycz, O.G, Weber-Shrikant, E, Zachariah, M, Kohli, R, Nader, N.D, Laftavi, M.R

“…Abstract Introduction Pulsatile pump perfusion of potential kidneys for transplantation is known to decrease the rate of delayed graft function (DGF) and…”
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Graft Arteriosclerosis and Glomerulosclerosis Correlate With Flow and Resistance to Machine Perfusion in Kidney Transplantation by Patel, S.K, Pankewycz, O.G, Weber-Shrikant, E, Zachariah, M, Kohli, R, Nader, N.D, Laftavi, M.R

“…Abstract Introduction Machine perfusion to preserve kidneys for transplantation has grown over the past decade with demonstrated diagnostic and therapeutic…”
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Transforming growth factor-β levels in human allograft chronic fibrosis correlate with rate of decline in renal function by CUHACI, B, KUMAR, M. S. A, STURGILL, B. C, PANKEWYCZ, O. G, BLOOM, R. D, PRATT, B, HAUSSMAN, G, LASKOW, D. A, ALIDOOST, M, GROTKOWSKI, C, CAHILL, K, BUTANI, L

“…Long-term renal transplant function is limited primarily by a progressive scarring process loosely termed "chronic rejection, chronic allograft nephropathy, or…”
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Polyreactive autoantibodies are nephritogenic in murine lupus nephritis by Pankewycz, OG, Migliorini, P, Madaio, MP

“…To characterize the antibodies that form glomerular immune deposits in lupus nephritis, immunoglobulin (Ig) was eluted from the perfused kidney cortices of…”
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Renal TGF-β regulation in spontaneously diabetic NOD mice with correlations in mesangial cells by Pankewycz, Oleh G., Guan, Jing-Xin, Bolton, W. Kline, Gomez, Ariel, Benedict, John F.

“…Renal TGF-β regulation in spontaneously diabetic NOD mice with correlations in mesangial cells. Diabetic nephropathy is characterized by excessive glomerular…”
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Simulect, calcineurin inhibitor, mycophenolate mofetil, and prednisone is more effective than OKT3, calcineurin inhibitor, hycophendate mofetil, and prednisone in African American kidney recipients in reducing acute rejections and prolonging graft survival by Kumar, A.M.S, Fa, K, Vankawala, R, Vora, M, Kode, R.K, Pankewycz, O.G, Lattavi, M.R, Fyfe, B, Damask, A.M, Ferry, E, Stabler, S, Tomeny, M.B, Phillips, K, Lingaraju, R, Kumar, M.S.A

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Simulect, neoral, cellcept, and prednisone in kidney recipients with delayed graft function: a prospective controlled study by Kumar, M.S.A, Kode, R.K, Pankewycz, O.G, Laftavi, M.R, Kumar, A.M.S, Damask, A.M, Vora, M, Tomeny, M.B, Ferry, E, Samartino, B.C, Sierka, D, Lingaraju, R.M, Fyfe, B

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Interleukin 2 counteracts the inhibition of cytotoxic T lymphocytes by cholera toxin in vitro and in vivo by Moscovitch-Lopatin, M, Petrillo, R J, Pankewycz, O G, Hadro, E, Bleackley, C R, Strom, T B, Wieder, K J

“…Cholera toxin irreversibly activates a 43-kDa guanosine triphosphate (GTP)-binding protein by adenosine diphosphate ribosylation, resulting in activation of…”
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Increased renal tubular expression of transforming growth factor beta in human allografts correlates with cyclosporine toxicity by Pankewycz, Oleh G., Miao, Li, Isaacs, Ross, Guan, Jing, Pruett, Tim, Haussmann, Gail, Sturgill, B.C.

“…Increased renal tubular expression of transforming growth factor beta in human allografts correlates with cyclosporine toxicity. Cyclosporine A (CsA) is a…”
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A protective NOD islet-infiltrating CD8+ T cell clone, I.S. 2.15, has in vitro immunosuppressive properties by Pankewycz, O G, Guan, J X, Benedict, J F

“…Type 1, insulin-dependent diabetes mellitus (IDDM) appears to result from a T cell-dependent destruction of insulin-producing pancreatic beta cells. In…”
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Immunotherapy using interleukin-2 diphtheria toxin chimer prolongs murine allografts by Mackie, J D, Pankewycz, O G, Hassarjian, R, Murphy, J R, Kelley, V E, Strom, T B

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Cytokines as mediators of autoimmune diabetes and diabetic complications by Pankewycz, O G, Guan, J X, Benedict, J F

“…Over the last several years, there has been a considerable and rapid expansion in our understanding of the cytokines. Insights into cytokine functions gained…”
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Cross-reactivity distinguishes serum and nephritogenic anti-DNA antibodies in human lupus from their natural counterparts in normal serum by Sabbaga, J, Pankewycz, O G, Lufft, V, Schwartz, R S, Madaio, M P

“…To distinguish the properties of anti-DNA antibodies in patients with lupus from those in normal individuals, we compared the ligand binding, idiotypic and…”
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The cascading, interrelated roles of interleukin-1, interleukin-2, and interleukin-6 in murine anti-CD3-driven T cell proliferation by Pankewycz, O G, Yui, M, Kelley, V E, Strom, T B

“…T cell stimulation occurs following interaction of T cell receptor (TcR) with processed antigen presented by autologous accessory cells (AC). The effects of…”
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Dose-related mechanisms of immunosuppression mediated by murine anti-CD3 monoclonal antibody in pancreatic islet cell transplantation and delayed-type hypersensitivity by Mackie, J D, Pankewycz, O G, Bastos, M G, Kelley, V E, Strom, T B

“…Although anti-CD3 mAb therapy is used extensively in clinical transplantation, the dose-related effects and mechanisms of action are not clearly defined. We…”
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Increased renal tubular expression of tranforming growth factor beta in human allografts correlates with cyclosporine toxicity by PANKEWYCZ, O. G, MIAO, L, ISAACS, R, GUAN, J, PRUETT, T, HAUSSMANN, G, STURGILL, B. C

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Anti-interleukin-2 receptor monoclonal antibody therapy induces anti-idiotypic antibodies in mice that block both in vitro and in vivo activity by Pankewycz, O G, Hassarjian, R, Chang, C, Strom, T B, Kelley, V E

“…Monoclonal antibodies (Mab) targeting certain T cell-surface proteins including the interleukin-2 (IL2) receptor molecule exert powerful immunosuppressive…”
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