Search Results - "PALTOO, Dina N"
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European Ancestry as a Risk Factor for Atrial Fibrillation in African Americans
Published in Circulation (New York, N.Y.) (16-11-2010)“…Despite a higher burden of standard atrial fibrillation (AF) risk factors, African Americans have a lower risk of AF than whites. It is unknown whether the…”
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Consent Codes: Upholding Standard Data Use Conditions
Published in PLoS genetics (01-01-2016)“…A systematic way of recording data use conditions that are based on consent permissions as found in the datasets of the main public genome archives (NCBI dbGaP…”
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The case for open science: rare diseases
Published in JAMIA open (01-10-2020)“…The premise of Open Science is that research and medical management will progress faster if data and knowledge are openly shared. The value of Open Science is…”
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Data use under the NIH GWAS Data Sharing Policy and future directions
Published in Nature genetics (01-09-2014)“…Dina Paltoo, Laura Lyman Rodriguez, Michael Feolo and colleagues present their analysis of the usefulness and impact of the first seven years of data sharing…”
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Technical desiderata for the integration of genomic data into Electronic Health Records
Published in Journal of biomedical informatics (01-06-2012)“…[Display omitted] ► Molecular sequence data will be an important component of EHRs. ► The volume and complexity of the data are key features. ► Desiderata for…”
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Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research
Published in JACC. Basic to translational science (2016)“…Summary Point-of-care technologies (POC or POCT) are enabling innovative cardiovascular diagnostics that promise to improve patient care across diverse…”
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Genome-wide association studies of the PR interval in African Americans
Published in PLoS genetics (01-02-2011)“…The PR interval on the electrocardiogram reflects atrial and atrioventricular nodal conduction time. The PR interval is heritable, provides important…”
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Candidate Gene Association Resource (CARe): Design, Methods, and Proof of Concept
Published in Circulation. Cardiovascular genetics (01-06-2010)“…BACKGROUND—The National Heart, Lung, and Blood Institute’s Candidate Gene Association Resource (CARe), a planned cross-cohort analysis of genetic variation in…”
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Genetics of coronary artery calcification among African Americans, a meta-analysis
Published in BMC genetics (19-07-2013)“…Coronary heart disease (CHD) is the major cause of death in the United States. Coronary artery calcification (CAC) scores are independent predictors of CHD…”
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Point-of-Care Technologies for Precision Cardiovascular Care and Clinical Research: National Heart, Lung, and Blood Institute Working Group
Published in JACC. Basic to translational science (01-01-2016)“…Point-of-care technologies (POC or POCT) are enabling innovative cardiovascular diagnostics that promise to improve patient care across diverse clinical…”
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Next generation analytic tools for large scale genetic epidemiology studies of complex diseases
Published in Genetic epidemiology (01-01-2012)“…Over the past several years, genome‐wide association studies (GWAS) have succeeded in identifying hundreds of genetic markers associated with common diseases…”
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Common Leptin Receptor Polymorphisms do not Modify the Effect of Alcohol Ingestion on Serum Leptin Levels in a Controlled Feeding and Alcohol Ingestion Study
Published in Cancer epidemiology, biomarkers & prevention (01-06-2005)“…We explored whether serum leptin response to alcohol ingestion was related to common leptin receptor gene polymorphisms, K109R (Lys 109 Arg), Q223R (Gln 223…”
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Genetic Simulation Tools for Post-Genome Wide Association Studies of Complex Diseases
Published in Genetic epidemiology (01-01-2015)“…ABSTRACT Genetic simulation programs are used to model data under specified assumptions to facilitate the understanding and study of complex genetic systems…”
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Genome-Wide Association Study of Cardiac Structure and Systolic Function in African Americans: The Candidate Gene Association Resource (CARe) Study
Published in Circulation. Cardiovascular genetics (01-02-2013)“…BACKGROUND—Using data from 4 community-based cohorts of African Americans, we tested the association between genome-wide markers (single-nucleotide…”
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Patterns in Cancer Incidence among American Indians/Alaska Natives, United States, 1992-1999
Published in Public health reports (1974) (01-07-2004)“…Objective. Cancer is a major public health concern in American Indian and Alaska Native (AI/AN) communities. However, information on the incidence of cancer is…”
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Association of Vasectomy and Prostate Cancer among Men in a Maryland Cohort
Published in Cancer causes & control (01-12-2005)“…Objectives: To evaluate the association of vasectomy with prostate cancer. Methods: Participants were male members of the CLUE II cohort followed since 1989…”
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Sequence variation within the 5′ regulatory regions of the vitamin D binding protein and receptor genes and prostate cancer risk
Published in The Prostate (01-08-2005)“…Background The vitamin D receptor (VDR) and binding protein (DBP) mediate the cellular transport, activity, and anti‐tumor action of 1,25‐dihydroxyvitamin D3…”
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Association between CBE, FOBT, and Pap smear adherence and mammography adherence among older low-income women
Published in Preventive medicine (01-06-2003)“…Adherence to regular and timely mammography screening, especially in older low-income women, continues to fall below objectives. The primary aim of this study…”
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Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project
Published in PLoS genetics (01-02-2011)“…Coronary heart disease (CHD) is the leading cause of mortality in African Americans. To identify common genetic polymorphisms associated with CHD and its risk…”
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