Search Results - "PALSSON, B. O"

Using the reconstructed genome-scale human metabolic network to study physiology and pathology by Bordbar, A., Palsson, B. O.

“…  Bordbar A, Palsson BO (University of California San Diego, La Jolla, CA, USA). Using the reconstructed genome‐scale human metabolic network to study…”
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Characterization of Metabolism in the Fe(III)-Reducing Organism Geobacter sulfurreducens by Constraint-Based Modeling by Mahadevan, R, Bond, D R, Butler, J E, Esteve-Nuñez, A, Coppi, M V, Palsson, B O, Schilling, C H, Lovley, D R

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The Escherichia coli MG1655 in Silico Metabolic Genotype: Its Definition, Characteristics, and Capabilities by Edwards, J. S., Palsson, B. O.

“…The Escherichia coli MG1655 genome has been completely sequenced. The annotated sequence, biochemical information, and other information were used to…”
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Pangenome reconstruction of Lactobacillaceae metabolism predicts species-specific metabolic traits by Ardalani, O, Phaneuf, P V, Mohite, O S, Nielsen, L K, Palsson, B O

“…Strains across the family form the basis for a trillion-dollar industry. Our understanding of the genomic basis for their key traits is fragmented, however,…”
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Meta-analysis Driven Strain Design for Mitigating Oxidative Stresses Important in Biomanufacturing by Phaneuf, PV, Kim, SH, Rychel, K, Rode, C, Beulig, F, Palsson, BO, Yang, L

“…As the availability of data sets increases, meta-analysis leveraging aggregated and interoperable data types is proving valuable. This study leveraged a…”
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Stoichiometric flux balance models quantitatively predict growth and metabolic by-product secretion in wild-type Escherichia coli W3110 by AMIT VARMA, PALSSON, B. O

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Properties of Metabolic Networks: Structure versus Function by Mahadevan, R., Palsson, B.O.

“…Biological data from high-throughput technologies describing the network components (genes, proteins, metabolites) and their associated interactions have…”
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Stoichiometric interpretation of Escherichia coli glucose catabolism under various oxygenation rates by AMIT VARMA, BOESCH, B. W, PALSSON, B. O

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Robustness analysis of the Escherichia coli metabolic network by EDWARDS, Jeremy S, PALSSON, Bernhard O

“…Genomic, biochemical, and strain-specific data can be assembled to define an in silico representation of the metabolic network for a select group of single…”
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Metabolic Pathway Analysis: Basic Concepts and Scientific Applications in the Post-genomic Era by Schilling, Christophe H., Schuster, Stefan, Palsson, Bernhard O., Heinrich, Reinhart

“…This article reviews the relatively short history of metabolic pathway analysis. Computer‐aided algorithms for the synthesis of metabolic pathways are…”
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Flux-balance analysis of mitochondrial energy metabolism: consequences of systemic stoichiometric constraints by Ramakrishna, R, Edwards, J S, McCulloch, A, Palsson, B O

“…Mitochondrial metabolism is a critical component in the functioning and maintenance of cellular organs. The stoichiometry of biochemical reaction networks…”
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Large-scale expansion of human stem and progenitor cells from bone marrow mononuclear cells in continuous perfusion cultures by Koller, Manfred R., Emerson, Stephen G., Palsson, Bernhard Ø

“…There is a growing consensus that clinical practice in the areas of bone marrow (BM) transplantation and gene therapy will rely on the ex vivo expansion of…”
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Elemental balancing of biomass and medium composition enhances growth capacity in high-density Chlorella vulgaris cultures by Mandalam, R.K. (University of Michigan, Ann Arbor, MI.), Palsson, B.O

“…The basic requirements for high-density photoautotrophic microalgal cultures in enclosed photobioreactors are a powerful light source and proper distribution…”
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Retroviral infection is limited by Brownian motion by Chuck, A S, Clarke, M F, Palsson, B O

“…Replication-defective retroviruses are frequently used as gene carriers for gene transfer into target cells. Here we show that the short half-lives of…”
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Toward Metabolic Phenomics: Analysis of Genomic Data Using Flux Balances by Schilling, Christophe H., Edwards, Jeremy S., Palsson, Bernhard O.

“…Small genome sequencing and annotations are leading to the definition of metabolic genotypes in an increasing number of organisms. Proteomics is beginning to…”
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Moloney murine leukemia virus-derived retroviral vectors decay intracellularly with a half-life in the range of 5.5 to 7.5 hours by Andreadis, S T, Brott, D, Fuller, A O, Palsson, B O

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Symmetry of initial cell divisions among primitive hematopoietic progenitors is independent of ontogenic age and regulatory molecules by SHIANG HUANG, LAW, P, FRANCIS, K, PALSSON, B. O, HO, A. D

“…We have developed a time-lapse camera system to follow the replication history and the fate of hematopoietic stem cells (HSC) at a single-cell level. Combined…”
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How will bioinformatics influence metabolic engineering? by Edwards, Jeremy S., Palsson, Bernhard O.

“…Ten microbial genomes have been fully sequenced to date, and the sequencing of many more genomes is expected to be completed before the end of the century. The…”
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In silico predictions of Escherichia coli metabolic capabilities are consistent with experimental data by Palsson, Bernhard O, Edwards, Jeremy S, Ibarra, Rafael U

“…A significant goal in the post-genome era is to relate the annotated genome sequence to the physiological functions of a cell. Working from the annotated…”
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A variational principle for computing nonequilibrium fluxes and potentials in genome-scale biochemical networks by Fleming, R.M.T., Maes, C.M., Saunders, M.A., Ye, Y., Palsson, B.Ø.

“…We derive a convex optimization problem on a steady-state nonequilibrium network of biochemical reactions, with the property that energy conservation and the…”
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