Search Results - "PALMER, Mike K"

Effect of statins on HDL-C: a complex process unrelated to changes in LDL-C: analysis of the VOYAGER Database by Barter, Philip J., Brandrup-Wognsen, Gunnar, Palmer, Mike K., Nicholls, Stephen J.

“…The relationship between statin-induced increases in HDL cholesterol (HDL-C) concentration and statin-induced decreases in LDL cholesterol (LDL-C) is unknown…”
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Extensive or Restricted Ultrasound Protocols to Measure Carotid Intima-Media Thickness: Analysis of Completeness Rates and Impact on Observed Rates of Change Over Time by Peters, Sanne A.E., MSc, den Ruijter, Hester M., PhD, Palmer, Mike K., PhD, Grobbee, Diederick E., MD, PhD, Crouse, John R., MD, O'Leary, Daniel H., MD, Evans, Gregory W., MA, Raichlen, Joel S., MD, Bots, Michiel L., MD, PhD

“…Background Ultrasound protocols to measure carotid intima-media thickness (CIMT) vary considerably with regard to carotid sites and angles that are assessed…”
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Effect of Rosuvastatin on the Echolucency of the Common Carotid Intima-Media in Low-Risk Individuals: The METEOR Trial by Lind, Lars, MD, Peters, Sanne A.E., MSc, den Ruijter, Hester M., PhD, Palmer, Mike K., PhD, Grobbee, Diederick E., MD, PhD, Crouse, John R., MD, O'Leary, Daniel H., MD, Evans, Gregory W., MA, Raichlen, Joel S., MD, Bots, Michiel L., MD, PhD

“…Background The echolucency of the carotid intima-media is related to increased cardiovascular risk factor levels, morbidity, and mortality. The aim of this…”
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Effect of Rosuvastatin on Progression of Carotid Intima-Media Thickness in Low-Risk Individuals With Subclinical Atherosclerosis: The METEOR Trial by Crouse, John R, Raichlen, Joel S, Riley, Ward A, Evans, Gregory W, Palmer, Mike K, O’Leary, Daniel H, Grobbee, Diederick E, Bots, Michiel L, METEOR Study Group, for the

“…CONTEXT Atherosclerosis is often advanced before symptoms appear and it is not clear whether treatment is beneficial in middle-aged individuals with a low…”
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The Use of Plaque Score Measurements to Assess Changes in Atherosclerotic Plaque Burden Induced by Lipid-Lowering Therapy Over Time: The METEOR Study by Peters, Sanne A.E., Dogan, Soner, Meijer, Rudy, Palmer, Mike K., Grobbee, Diederick E., Crouse, John R. 3rd, O'Leary, Daniel H., Evans, Gregory W., Raichlen, Joel S., Bots, Michiel L.

“…Aim: To evaluate whether plaque scoring measurements are able to track changes in atherosclerotic plaque burden over time and to study whether this is affected…”
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Measuring effects on intima media thickness: An evaluation of rosuvastatin in subclinical atherosclerosis: The rationale and methodology of the METEOR study by CROUSE, John Robert, GROBBEE, Diederick E, OLEARY, Daniel H, BOTS, Michiel L, EVANS, Gregory W, PALMER, Mike K, RILEY, Ward A, RAICHLEN, Joel S

“…Increased carotid intima media thickness (IMT) is associated with established coronary heart disease (CHD) and is a marker of atherosclerosis. Statins are an…”
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Multiple imputation of missing repeated outcome measurements did not add to linear mixed-effects models by Peters, Sanne A.E, Bots, Michiel L, den Ruijter, Hester M, Palmer, Mike K, Grobbee, Diederick E, Crouse, John R, O’Leary, Daniel H, Evans, Gregory W, Raichlen, Joel S, Moons, Karel G.M, Koffijberg, Hendrik

“…Abstract Objective To assess the added value of multiple imputation (MI) of missing repeated outcomes measures in longitudinal data sets analyzed with linear…”
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Efficacy, safety and effect on biomarkers related to cholesterol and lipoprotein metabolism of rosuvastatin 10 or 20 mg plus ezetimibe 10 mg vs. simvastatin 40 or 80 mg plus ezetimibe 10 mg in high-risk patients: Results of the GRAVITY randomized study by Ballantyne, Christie M, Hoogeveen, Ron C, Raya, Joe L, Cain, Valerie A, Palmer, Mike K, Karlson, Björn W

“…Abstract Objectives Combination therapy may help high-risk patients achieve low-density lipoprotein cholesterol (LDL-C) goals. Impact of rosuvastatin 10 or…”
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Achievement of 2011 European low-density lipoprotein cholesterol (LDL-C) goals of either <70 mg/dl or ≥50% reduction in high-risk patients: Results from VOYAGER by Karlson, Björn W, Nicholls, Stephen J, Lundman, Pia, Palmer, Mike K, Barter, Philip J

“…Abstract Objective Guidelines published in 2011 by the European Atherosclerosis Society and the European Society of Cardiology recommend a goal of either…”
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Algorithms to measure carotid intima-media thickness in trials: a comparison of reproducibility, rate of progression and treatment effect by DOGAN, Soner, PLANTINGA, Yvonne, CROUSE, John R, EVANS, Gregory W, RAICHLEN, Joel S, O'LEARY, Daniel H, PALMER, Mike K, GROBBEE, Diederick E, BOTS, Michiel L

“…Current ultrasound protocols to measure carotid intima-media thickness (CIMT) in trials differ considerably. The best CIMT protocol would be one that combines…”
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Achievement of LDL-C goals depends on baseline LDL-C and choice and dose of statin: An analysis from the VOYAGER database by Palmer, Mike K, Nicholls, Stephen J, Lundman, Pia, Barter, Philip J, Karlson, Björn W

“…Background Reducing low-density lipoprotein cholesterol (LDL-C) levels decreases cardiovascular risk in direct proportion to the decrease in LDL-C. Design The…”
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Asymmetrical distribution of atherosclerosis in the carotid artery: identical patterns across age, race, and gender by Tajik, Parvin, Meijer, Rudy, Duivenvoorden, Raphaël, Peters, Sanne AE, Kastelein, John J, Visseren, Frank J, Crouse, John R, Palmer, Mike K, Raichlen, Joel S, Grobbee, Diederick E, Bots, Michiel L

“…Background: Small autopsy studies and clinical practice indicated that carotid atherosclerosis develops in an asymmetrical helical pattern coinciding with…”
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Effect of number of ultrasound examinations on the assessment of carotid intima-media thickness changes over time: the example of the METEOR study by PETERS, Sanne A. E, PALMER, Mike K, GROBBEE, Diederick E, CROUSE, John R, EVANS, Gregory W, RAICHLEN, Joel S, BOTS, Michiel L

“…To evaluate the effect of the number and positioning during follow-up of ultrasound examinations on the rate of change in carotid intima-media thickness (CIMT)…”
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Sample size requirements in trials using repeated measurements and the impact of trial design by Peters, Sanne A.E., Palmer, Mike K., den Ruijter, Hester M., Grobbee, Diederick E., Crouse III, John R., O'Leary, Daniel H., Evans, Gregory W., Raichlen, Joel S., Bots, Michiel L.

“…Abstract Objective: Sample size calculations for clinical trials generally use expected changes between groups, and variances obtained from the literature…”
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Biologically implausible carotid intima-media thickness measurement values: effects on rate of change over time by Peters, Sanne A.E., den Ruijter, Hester M., Palmer, Mike K., Grobbee, Diederick E., Crouse, John R., O'Leary, Daniel H., Evans, Gregory W., Raichlen, Joel S., Bots, Michiel L.

“…Abstract Objective:Carotid intima-media thickness (CIMT) is a marker of atherosclerosis that is commonly used to assess the effect of therapeutic…”
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Achievement of ATP III Combined LDL-C and Non-HDL-C Goals of <100 and <130 mg/dL or <70 and <100 mg/dL with 3 Different Statins: Results from VOYAGER by Toth, Peter P., MD, PhD, Barter, Philip J., MBBS, PhD, Palmer, Mike K., PhD, Carlson, Bjorn W., MD

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Does baseline carotid intima-media thickness modify the effect of rosuvastatin when compared with placebo on carotid intima-media thickness progression? The METEOR study by Crouse, 3rd, John R, Bots, Michiel L, Evans, Gregory W, Palmer, Mike K, O'Leary, Daniel H, Grobbee, Diederick E, Raichlen, Joel S

“…Many studies have used carotid intima-media thickness (CIMT) measurement to study atherosclerosis and the efficacy of interventions. The placebo-controlled…”
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Carotid intima-media thickness in low-risk individuals with asymptomatic atherosclerosis: baseline data from the METEOR study by Crouse, John R., Grobbee, Diederick E., O’Leary, Daniel H., Bots, Michiel L., Evans, Gregory W., Palmer, Mike K., Riley, Ward A., Raichlen, Joel S.

“…ABSTRACT Objective: Carotid intima-media thickness (CIMT) is an index for changes in atherosclerosis burden and changes in CIMT may relate to clinical events…”
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Abstract 2648: Design of Carotid Intima-Media Thickness Trials by Evans, Gregory W, Palmer, Mike K, O’Leary, Daniel H, Crouse, John R, Bots, Michiel L, Grobbee, Diederick E, Raichlen, Joel S

“…Abstract only Carotid artery intima-media thickness (CIMT) assessed by B-mode ultrasound is an accepted marker for subclinical atherosclerosis commonly used in…”
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Abstract 194: Rosuvastatin Reduces Progression of Carotid Atherosclerosis within 12 Months of Treatment: The METEOR Trial by Bots, Michiel L, Raichlen, Joel S, Evans, Gregory W, Palmer, Mike K, O’Leary, Daniel H, Grobbee, Diederick E, Crouse, John R

“…Abstract only Background: In several statin trials, vascular event rates for treatment groups begin to separate 1 year after commencement of treatment. For…”
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