Search Results - "PALMEIRA, C. M"

Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice by Teodoro, J S, Zouhar, P, Flachs, P, Bardova, K, Janovska, P, Gomes, A P, Duarte, F V, Varela, A T, Rolo, A P, Palmeira, C M, Kopecký, J

“…Objective: Besides their role in lipid absorption, bile acids (BAs) can act as signalling molecules. Cholic acid was shown to counteract obesity and associated…”
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Bile acids affect liver mitochondrial bioenergetics : Possible relevance for cholestasis therapy by ROLO, Anabela P, OLIVEIRA, Paulo J, MORENO, Antonio J. M, PALMEIRA, Carlos M

“…It has been pointed out that intracellular accumulation of bile acids cause hepatocyte injury in cholestatic disease process. This study was aimed to test if…”
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Cardioselective and cumulative oxidation of mitochondrial DNA following subchronic doxorubicin administration by Serrano, J., Palmeira, C.M., Kuehl, D.W., Wallace, K.B.

“…We recently reported the preferential accumulation of 8-hydroxydeoxyguanosine (8OHdG) adducts in cardiac mitochondrial DNA (mtDNA) following acute intoxication…”
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Impairment of mitochondrial energy metabolism of two marine fish by in vitro mercuric chloride exposure by Mieiro, C.L., Pardal, M., Duarte, A., Pereira, E., Palmeira, C.M.

“…•Hg levels usually found in contaminated environments may compromise fish metabolism.•Hg impairs both the oxidative phosphorylation and the electron transport…”
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Preferential oxidation of cardiac mitochondrial DNA following acute intoxication with doxorubicin by Palmeira, C.M, Serrano, J, Kuehl, D.W, Wallace, K.B

“…The purpose of this investigation was to determine whether acute doxorubicin intoxication causes a preferential accumulation of 8-hydroxydeoxyguanosine (8OHdG)…”
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Benzoquinone Inhibits the Voltage-Dependent Induction of the Mitochondrial Permeability Transition Caused by Redox-Cycling Naphthoquinones by Palmeira, Carlos M., Wallace, Kendall B.

“…The mitochondrial permeability pore is subject to regulation by a thiol-dependent voltage sensor (Petronilli, V., Costantini, P., Scorrano, L., Colonna, R.,…”
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Dibenzofuran-induced mitochondrial dysfunction: Interaction with ANT carrier by Duarte, F.V., Gomes, A.P., Teodoro, J.S., Varela, A.T., Moreno, A.J.M., Rolo, A.P., Palmeira, C.M.

“…•DBF exposure negatively affects liver mitochondria phosphorylative system.•DBF increases the threshold to the induction of the mitochondrial permeability…”
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Mitochondrially-mediated toxicity of bile acids by Palmeira, Carlos M., Rolo, Anabela P.

“…In the healthy hepatocyte, uptake of bile acids across the basolateral membrane and export via the canalicular export pump, are tightly coupled. Impairment of…”
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Acrylic acid induces the glutathione-independent mitochondrial permeability transition in vitro by CUSTODIO, J. B. A, PALMEIRA, C. M, MORENO, A. J, WALLACE, K. B

“…Acrylic acid (AA) is used widely in the synthesis of esters essential in the production of paints, adhesives, plastics, and coatings. The minimal systemic…”
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Alterations of liver mitochondrial bioenergetics in diabetic Goto-Kakizaki rats by Ferreira, F.M.L., Palmeira, C.M., Seiça, R., Santos, M.S.

“…Respiratory indexes and the transmembrane electrical potential (ΔΨ) were evaluated in mitochondrial preparations from 6-month-old Goto-Kakizaki (GK) and Wistar…”
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Interactions of herbicides 2,4-D and dinoseb with liver mitochondrial bioenergetics by Palmeira, C M, Moreno, A J, Madeira, V M

“…The herbicides 2,4-D (2,4-dichlorophenoxyacetic acid) and dinoseb (2-sec-butyl-4,6-dinitrophenol), were tested in mitochondria because they are putative toxins…”
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Cholestasis induced by chronic treatment with α-naphthyl-isothiocyanate (ANIT) affects rat renal mitochondrial bioenergetics by FERREIRA, F. M, OLIVEIRA, P. J, ROLO, A. P, SANTOS, M. S, MORENO, A. J, DA CUNHA, M. F, SEICA, R, PALMEIRA, C. M

“…Chronic cholestasis is characteristic of many human liver diseases. Renal injury has been often associated with this type of disease. The aim of this study was…”
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Evaluation of olive oil mill wastewater toxicity on the mitochondrial bioenergetics after treatment with Candida oleophila by Peixoto, F., Martins, F., Amaral, C., Gomes-Laranjo, J., Almeida, J., Palmeira, C.M.

“…In a previous work the ability of Candida oleophila to use phenolic compounds as sole carbon and energy source at high concentrations without an additional…”
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Thiols metabolism is altered by the herbicides paraquat, dinoseb and 2,4-D: A study in isolated hepatocytes by Palmeira, Carlos M., Moreno, António J., Madeira, Vítor M.C.

“…This report is an extension and complement of a previous study reporting the effect of three herbicides (paraquat, dinoseb and 2,4-D) on cell viability, GSH…”
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Metabolic alterations in hepatocytes promoted by the herbicides paraquat, dinoseb and 2,4-D by PALMEIRA, C. M, MORENO, A. J, MADEIRA, V. M. C

“…The cytotoxic effects of the herbicides paraquat (1,1'-dimethyl-4,4'-bipyridylium dichloride), dinoseb (2-sec-butyl-4,6-dinitrophenol) and 2,4-D…”
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Doxorubicin-induced persistent oxidative stress to cardiac myocytes by Zhou, Shaoyu, Palmeira, Carlos M, Wallace, Kendall B

“…We recently reported a cardioselective and cumulative oxidation of cardiac mitochondrial DNA (mtDNA) following subchronic administration of doxorubicin to…”
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Membrane lipid peroxidation induces changes in gamma-[3H]aminobutyric acid transport and calcium uptake by synaptosomes by Palmeira, C M, Santos, M S, Carvalho, A P, Oliveira, C R

“…In the present study, we analyze the effect of Fe2+/ascorbate-induced lipid peroxidation on Ca(2+)-dependent and Ca(2+)-independent release and on the uptake…”
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Age-related alterations in liver mitochondrial bioenergetics of diabetic Goto-Kakizaki rats by FERREIRA, F. M. L, SEICA, R, SANTOS, M. S, PALMEIRA, C. M

“…Type 2 diabetes mellitus is one of the most common chronic metabolic diseases in man. Due to long-term complications of the disease, severely decreasing the…”
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Chenodeoxycholate is a potent inducer of the permeability transition pore in rat liver mitochondria by Rolo, A P, Oliveira, P J, Moreno, A J, Palmeira, C M

“…Several reports support the concept that bile acids may be cytotoxic during cholestatic disease process by causing mitochondrial dysfunction. Here we report…”
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Induction of the Mitochondrial Permeability Transition in Vitro by Short-Chain Carboxylic Acids by Palmeira, C.M., Rana, M.I., Frederick, C.B., Wallace, K.B.

“…We recently reported that acrylic acid (AA) induces the MPT in vitro, which we suggested might be a critical event in the acute inflammatory and hyperplastic…”
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