Search Results - "PALEOLOG, E"

Role of angiogenesis in bone and joint diseases by Paleolog, E

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Adenoviral delivery of soluble VEGF receptor 1 (sFlt-1) abrogates disease activity in murine collagen-induced arthritis by AFUWAPE, A. O, FELDMANN, M, PALEOLOG, E. M

“…The angiogenic factor VEGF promotes synovitis and bone erosion in rheumatoid arthritis (RA). Previously, we have demonstrated that VEGF expression correlates…”
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What have we learnt from targeted anti-TNF therapy? by Feldmann, M, Williams, R O, Paleolog, E

“…Anti-tumour necrosis factor (anti-TNF) therapy of patients with rheumatoid arthritis dates back to 1992, when the first proof-of-principle trials were…”
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Venous hypoxia: a poorly studied etiological factor of varicose veins by Lim, C S, Gohel, M S, Shepherd, A C, Paleolog, E, Davies, A H

“…Venous hypoxia has long been postulated as a potential cause of varicosity formation. This article aimed to review the development of this hypothesis,…”
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Adenovirus-Mediated VEGF Gene Therapy Enhances Venous Thrombus Recanalization and Resolution by Modarai, B, Humphries, J, Gossage, J A, Waltham, M, Burnand, K G, Kanaganayagam, G S, Afuwape, A, Paleolog, E, Smith, A, Wadoodi, A

“…OBJECTIVE—Rapid thrombus recanalization reduces the incidence of post–thrombotic complications. This study aimed to discover whether adenovirus-mediated…”
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Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1 by BAINBRIDGE, J. W. B, MISTRY, A, DE ALWIS, M, PALEOLOG, E, BAKER, A, THRASHER, A. J, ALI, R. R

“…Retinal angiogenesis is a central feature of the leading causes of blindness. Current treatments for these conditions are of limited efficacy and cause…”
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Diagnostic strategy for the assessment of rheumatoid vasculitis by Voskuyl, A E, Hazes, J M W, Zwinderman, A H, Paleolog, E M, van der Meer, F J M, Daha, M R, Breedveld, F C

“…Objective: To determine the clinical features associated with histologically proven rheumatoid vasculitis (HRV) and the additional diagnostic value of…”
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Inhibition of retinal neovascularisation by gene transfer of soluble VEGF receptor sFlt-1 by Bainbridge, JWB, Mistry, A, De Alwis, M, Paleolog, E, Baker, A, Thrasher, A J, Ali, R R

“…Retinal angiogenesis is a central feature of the leading causes of blindness. Current treatments for these conditions are of limited efficacy and cause…”
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Inhibitory Effect of TIMP Influences the Morphology of Varicose Veins by Aravind, B, Saunders, B, Navin, T, Sandison, A, Monaco, C, Paleolog, E.M, Davies, A.H

“…Abstract Objectives Imbalance of matrix metalloproteinase enzymes (MMP) and their inhibitors (TIMPs) may contribute to the development of varicose veins. We…”
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ANGIOGENESIS: A CRITICAL PROCESS IN THE PATHOGENESIS OF RA— A ROLE FOR VEGF? by Paleolog, E M

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Investigation of convergence between Epidermal Growth Factor and hypoxia on the pro-angiogenic switch in colorectal cancer by Khong, Tak, Paleolog, E, Dawson, P

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In vitro target validation and in vivo efficacy of p38 MAP kinase inhibition in established chronic collagen-induced arthritis model: a pre-clinical study by TRIANTAPHYLLOPOULOS, K, MADDEN, L, RIOJA, I, ESSEX, D, BUCKTON, J, MALHOTRA, R, RAY, K, BINKS, M, PALEOLOG, E. M

“…The aim of the present study was to determine the in vivo efficacy of p38 mitogen-activated protein kinase (MAPK) inhibitors, namely GW856553X and GSK678361,…”
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Vascular endothelial growth factor in human periodontal disease by Booth, V., Young, S., Cruchley, A., Taichman, N. S., Paleolog, E.

“…Vascular endothelial growth factor (VEGF) is a multifunctional angiogenic cytokine of importance in inflammation and wound healing but its presence in chronic…”
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Is NF-κB a useful therapeutic target in rheumatoid arthritis? by Feldmann, M, Andreakos, E, Smith, C, Bondeson, J, Yoshimura, S, Kiriakidis, S, Monaco, C, Gasparini, C, Sacre, S, Lundberg, A, Paleolog, E, Horwood, N J, Brennan, F M, Foxwell, B M J

“…There is increasing evidence that NF-κB is a major, if not the major transcription factor regulating inflammation and immunity. While this implies that…”
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Circulating endothelial progenitor cells as a link between synovial vascularity and cardiovascular mortality in rheumatoid arthritis by Akhavani, M. A., Larsen, H., Paleolog, E.

“…Cardiovascular disease refers to the class of diseases that involve the heart and or blood vessels (arteries and veins). Most Western countries face high and…”
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Prolonged Mechanical Stretch is Associated with Upregulation of Hypoxia-inducible Factors and Reduced Contraction in Rat Inferior Vena Cava by Lim, C.S, Qiao, X, Mam, V, Xia, Y, Raffetto, J.D, Paleolog, E, Davies, A.H, Khalil, R.A

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The transcription factor Erg represses ICAM-1 expression and vascular inflammation by Sperone, A, Dryden, N, Birdsey, G.M, Madden, L.E, Evans, P, Mason, J.C, Boyle, J, Paleolog, E, Haskard, D.O, Randi, A.M

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Human neutrophils secrete vascular endothelial growth factor by Taichman, Norton S., Young, Sylvia, Cruchley, Alan T., Taylor, Peter, Paleolog, Ewa

“…Vascular endothelial growth factor (VEGF) is a multifunctional cytokine that plays a pivotal role in mediating neovascularization as well as other endothelial…”
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VEGF release is associated with reduced oxygen tensions in experimental inflammatory arthritis by Etherington, P J, Winlove, P, Taylor, P, Paleolog, E, Miotla, J M

“…The contribution of local VEGF production and subsequent angiogenesis within the synovial membrane to the propagation of arthritis is unclear. The relationship…”
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The role of hypoxia in rheumatoid hand disease by Akhavani, M.A, Paleolog, E, Kang, N

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