Search Results - "PAKASKI, Magdolna"
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A Speech Recognition-based Solution for the Automatic Detection of Mild Cognitive Impairment from Spontaneous Speech
Published in Current Alzheimer research (01-01-2018)“…Even today the reliable diagnosis of the prodromal stages of Alzheimer's disease (AD) remains a great challenge. Our research focuses on the earliest…”
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Speech-related parameters are sensitive measures of acetylcholinesterase inhibitor therapy in mild Alzheimer's disease
Published in PloS one (20-08-2024)“…Our aim was to find out whether speech-related temporal parameters (SRTPs) are sensitive indicators of the clinical outcome in acetylcholinesterase (AChE)…”
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Identifying Mild Cognitive Impairment and mild Alzheimer’s disease based on spontaneous speech using ASR and linguistic features
Published in Computer speech & language (01-01-2019)“…•Novel acoustic feature extraction scheme for mild cognitive impairment and Alzheimer’s.•Distinguishing MCI and AD from healthy controls.•Combination of…”
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The Role of Silence in Verbal Fluency Tasks - A New Approach for the Detection of Mild Cognitive Impairment
Published in Journal of the International Neuropsychological Society (01-01-2023)“…Most recordings of verbal fluency tasks include substantial amounts of task-irrelevant content that could provide clinically valuable information for the…”
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Linguistic Parameters of Spontaneous Speech for Identifying Mild Cognitive Impairment and Alzheimer Disease
Published in Computational linguistics - Association for Computational Linguistics (04-04-2022)“…In this article, we seek to automatically identify Hungarian patients suffering from mild cognitive impairment (MCI) or mild Alzheimer disease (mAD) based on…”
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Application of BisANS fluorescent dye for developing a novel protein assay
Published in PloS one (19-04-2019)“…In many biology- and chemistry-related research fields and experiments the quantification of the peptide and/or protein concentration in samples are essential…”
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Temporal Speech Parameters Indicate Early Cognitive Decline in Elderly Patients With Type 2 Diabetes Mellitus
Published in Alzheimer disease and associated disorders (01-04-2022)“…The earliest signs of cognitive decline include deficits in temporal (time-based) speech characteristics. Type 2 diabetes mellitus (T2DM) patients are more…”
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Association between a variant of the sigma-1 receptor gene and Alzheimer's disease
Published in Neuroscience letters (31-05-2012)“…► We investigated SIGMAR1 gene polymorphisms in Alzheimer's disease (AD). ► Rs1799729 and rs1800866 polymorphisms were in nearly complete linkage…”
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Genetic analysis of the RELN gene: Gender specific association with Alzheimer’s disease
Published in Psychiatry research (15-12-2015)“…Abstract Association between genetic variants of the reelin ( RELN ) gene and the risk for developing Alzheimer's disease (AD) was examined in a sample of 432…”
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Telltale silence: temporal speech parameters discriminate between prodromal dementia and mild Alzheimer's disease
Published in Clinical linguistics & phonetics (03-08-2021)“…This study presents a novel approach for the early detection of mild cognitive impairment (MCI) and mild Alzheimer's disease (mAD) in the elderly. Participants…”
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Cross-lingual detection of mild cognitive impairment based on temporal parameters of spontaneous speech
Published in Computer speech & language (01-09-2021)“…•Distinguishing Mild Cognitive Impairment (MCI) subjects from healthy controls.•Cross-lingual study using English and Hungarian subjects.•Acoustic features are…”
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Association between the ABCG2 C421A polymorphism and Alzheimer's disease
Published in Neuroscience letters (29-08-2013)“…•ABCG2 C421A (rs2231142) polymorphism was examined in Alzheimer's disease (AD).•An increased susceptibility to AD associated with ABCG2 C/C genotype was…”
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Temporal parameters of spontaneous speech in Alzheimer's disease
Published in International journal of speech language pathology (01-02-2010)“…This paper reports on four temporal parameters of spontaneous speech in three stages of Alzheimer's disease (mild, moderate, and severe) compared to…”
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Proteomic analysis of cerebrospinal fluid in Alzheimer's disease: wanted dead or alive
Published in Journal of Alzheimer's disease (01-01-2015)“…Clinical diagnosis of Alzheimer's disease (AD) relying on symptomatic features has a low specificity, emphasizing the importance of the pragmatic use of…”
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Automatic screening of mild cognitive impairment and Alzheimer’s disease by means of posterior-thresholding hesitation representation
Published in Computer speech & language (01-09-2022)“…Dementia is a chronic or progressive clinical syndrome, characterized by the deterioration of problem-solving skills, memory and language. In Mild Cognitive…”
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ABCB1 C3435T Polymorphism Influences the Risk for Alzheimer’s Disease
Published in Journal of molecular neuroscience (01-12-2014)“…To evaluate the association of ATP-binding cassette subfamily B member 1 ( ABCB1 ) genetic variants with the susceptibility to Alzheimer’s disease (AD), we…”
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Dementia in Hungary: General practitioners' routines and perspectives regarding early recognition
Published in The European journal of general practice (01-12-2020)“…Undetected dementia in primary care is a global problem. Since general practitioners (GPs) act as the first step in the identification process, examining their…”
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Association between the 9 repeat allele of the dopamine transporter 40 bp variable tandem repeat polymorphism and Alzheimer’s disease
Published in Psychiatry research (15-12-2014)“…Abstract A case-control study was performed to investigate the association between the dopamine transporter (DAT) gene ( SLC6A3 ) rs28363170 polymorphism and…”
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Serotonin transporter and serotonin receptor 2A gene polymorphisms in Alzheimer's disease
Published in Neuroscience letters (08-02-2013)“…► Serotonin system gene variants (SLC6A4, HTR2A) were investigated in Alzheimer's disease (AD). ► No association was found between 5-HTTLPR, STin2-VNTR or…”
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Knowledge of general practitioners on dementia and mild cognitive impairment: a cross-sectional, questionnaire study from Hungary
Published in Educational gerontology (03-08-2019)“…General practitioners (GPs) play a pivotal role in dementia recognition, yet research suggests that dementia often remains undetected in primary care. Lack of…”
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