Search Results - "PAINE, R. III"

Prediction of Obstructive Lung Disease from Chest Radiographs via Deep Learning Trained on Pulmonary Function Data by Schroeder, Joyce D, Bigolin Lanfredi, Ricardo, Li, Tao, Chan, Jessica, Vachet, Clement, Paine Iii, Robert, Srikumar, Vivek, Tasdizen, Tolga

“…Chronic obstructive pulmonary disease (COPD), the third leading cause of death worldwide, is often underdiagnosed. To develop machine learning methods to…”
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Defining Chronic Mucus Hypersecretion Using the CAT in the SPIROMICS Cohort by Stott-Miller, Marni, Müllerová, Hana, Miller, Bruce, Tabberer, Maggie, El Baou, Céline, Keeley, Tom, Martinez, Fernando J, Han, Meilan, Dransfield, Mark, Hansel, Nadia N, Cooper, Christopher B, Woodruff, Prescott, Ortega, Victor E, Comellas, Alejandro P, Paine Iii, Robert, Kanner, Richard E, Anderson, Wayne, Drummond, M Bradley, Kim, Victor, Tal-Singer, Ruth, Lazaar, Aili L

“…Chronic cough and phlegm are frequently reported chronic obstructive pulmonary disease (COPD) symptoms. Prior research classified chronic mucus hypersecretion…”
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Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis [Corrigendum] by Barjaktarevic, Igor, Buhr, Russell G, Wang, Xiaoyan, Hu, Scott, Couper, David, Anderson, Wayne, Kanner, Richard E, Paine III, Robert, Bhatt, Surya P, Bhakta, Nirav R, Arjomandi, Mehrdad, Kaner, Robert J, Pirozzi, Cheryl S, Curtis, Jeffrey L, O'Neal, Wanda K, Woodruff, Prescott G, Han, MeiLan K, Martinez, Fernando J, Hansel, Nadia, Wells, James Michael, Ortega, Victor E, Hoffman, Eric, Doerschuk, Claire M, Kim, Victor, Dransfield, Mark T, Drummond, M Bradley, Bowler, Russell, Criner, Gerard, Christenson, Stephanie A, Ronish, Bonnie, Peters, Stephen, Krishnan, Jerry A, Tashkin, Donald, Cooper, Christopher

“…Funding This study was supported by R01HL125432-01A1 (MBD), T32HL007106-41 (RMB), and TL1TR001883-01 (RGB). SPIROMICS was supported by contracts from the…”
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Alveolar macrophages are required for protective pulmonary defenses in murine Klebsiella pneumonia: elimination of alveolar macrophages increases neutrophil recruitment but decreases bacterial clearance and survival by BROUG-HOLUB, E, TOEWS, G. B, VAN IWAARDEN, J. F, STRIETER, R. M, KUNKEL, S. L, PAINE, R. III, STANDIFORD, T. J

“…Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
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MCP-1 expression by rat type II alveolar epithelial cells in primary culture by Paine, R, 3d, Rolfe, MW, Standiford, TJ, Burdick, MD, Rollins, BJ, Strieter, RM

“…Recruitment and activation of mononuclear phagocytes are potentially critical regulatory events for control of pulmonary inflammation. Located at the boundary…”
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Signal transduction via CD4, CD8, and CD28 in mature and immature thymocytes. Implications for thymic selection by Turka, LA, Linsley, PS, Paine, R, 3d, Schieven, GL, Thompson, GB, Ledbetter, JA

“…The positive and negative selection of immature thymocytes that shapes the mature T cell repertoire appears to occur at an intermediate stage of development…”
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CD8 cells play a critical role in delayed type hypersensitivity to intact Cryptococcus neoformans by Mody, CH, Paine, R, 3rd, Jackson, C, Chen, GH, Toews, GB

“…Although cell-mediated immunity is critical for optimal host defense to C. neoformans, the role of T lymphocyte subsets is complex and poorly understood. CD8…”
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Legionella pneumophila Replicates within Rat Alveolar Epithelial Cells by Mody, Christopher H., Paine, Robert, Shahrabadi, M. Shamsi, Simon, Richard H., Pearlman, Eric, Eisenstein, Barry I., Toews, Galen B.

“…Legionella pneumophila replicates in the distal pulmonary airspace, causing legionnaires' pneumonia. Legionella organisms replicate within alveolar macrophages…”
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Clinical Significance of Bronchodilator Responsiveness Evaluated by Forced Vital Capacity in COPD: SPIROMICS Cohort Analysis by Barjaktarevic, Igor Z, Buhr, Russell G, Wang, Xiaoyan, Hu, Scott, Couper, David, Anderson, Wayne, Kanner, Richard E, Paine Iii, Robert, Bhatt, Surya P, Bhakta, Nirav R, Arjomandi, Mehrdad, Kaner, Robert J, Pirozzi, Cheryl S, Curtis, Jeffrey L, O'Neal, Wanda K, Woodruff, Prescott G, Han, MeiLan K, Martinez, Fernando J, Hansel, Nadia, Wells, James Michael, Ortega, Victor E, Hoffman, Eric A, Doerschuk, Claire M, Kim, Victor, Dransfield, Mark T, Drummond, M Bradley, Bowler, Russell, Criner, Gerard, Christenson, Stephanie A, Ronish, Bonnie, Peters, Stephen P, Krishnan, Jerry A, Tashkin, Donald P, Cooper, Christopher B

“…Bronchodilator responsiveness (BDR) is prevalent in COPD, but its clinical implications remain unclear. We explored the significance of BDR, defined by…”
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Longitudinal Imaging-Based Clusters in Former Smokers of the COPD Cohort Associate with Clinical Characteristics: The SubPopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) by Zou, Chunrui, Li, Frank, Choi, Jiwoong, Haghighi, Babak, Choi, Sanghun, Rajaraman, Prathish K, Comellas, Alejandro P, Newell, John D, Lee, Chang Hyun, Barr, R Graham, Bleecker, Eugene, Cooper, Christopher B, Couper, David, Han, Meilan, Hansel, Nadia N, Kanner, Richard E, Kazerooni, Ella A, Kleerup, Eric C, Martinez, Fernando J, O'Neal, Wanda, Paine, 3rd, Robert, Rennard, Stephen I, Smith, Benjamin M, Woodruff, Prescott G, Hoffman, Eirc A, Lin, Ching-Long

“…Quantitative computed tomography (qCT) imaging-based cluster analysis identified clinically meaningful COPD former-smoker subgroups (clusters) based on…”
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Role of Granulocyte Macrophage Colony-Stimulating Factor in Host Defense Against Pulmonary Cryptococcus neoformans Infection during Murine Allergic Bronchopulmonary Mycosis by Chen, Gwo-Hsiao, Olszewski, Michal A, McDonald, Roderick A, Wells, Jason C, Paine, Robert, Huffnagle, Gary B, Toews, Galen B

“…We investigated the role of granulocyte macrophage colony-stimulating factor (GM-CSF) in host defense in a murine model of pulmonary cryptococcosis induced by…”
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Sublethal Hyperoxia Impairs Pulmonary Innate Immunity by Baleeiro, Carlos E. O, Wilcoxen, Steven E, Morris, Susan B, Standiford, Theodore J, Paine, Robert, III

“…Supplemental oxygen is often required in the treatment of critically ill patients. The impact of hyperoxia on pulmonary host defense is not well-established…”
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Hyperoxia Mediates Acute Lung Injury and Increased Lethality in Murine Legionella Pneumonia: The Role of Apoptosis by Tateda, Kazuhiro, Deng, Jane C, Moore, Thomas A, Newstead, Michael W, Paine, Robert, III, Kobayashi, Nobuyuki, Yamaguchi, Keizo, Standiford, Theodore J

“…Legionella pneumophila is a major cause of life-threatening pneumonia, which is characterized by a high incidence of acute lung injury and resultant severe…”
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Defective Phagocytosis and Clearance of Pseudomonas aeruginosa in the Lung Following Bone Marrow Transplantation by Ojielo, Charles I, Cooke, Kenneth, Mancuso, Pete, Standiford, Theodore J, Olkiewicz, Krystyna M, Clouthier, Shawn, Corrion, Leigh, Ballinger, Megan N, Toews, Galen B, Paine, Robert, III, Moore, Bethany B

“…Bone marrow transplantation (BMT) is an important therapeutic option for a variety of malignant and nonmalignant disorders. Unfortunately, BMT recipients are…”
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GM-CSF Regulates Bleomycin-Induced Pulmonary Fibrosis Via a Prostaglandin-Dependent Mechanism by Moore, Bethany B, Coffey, Michael J, Christensen, Paul, Sitterding, Stephanie, Ngan, Rose, Wilke, Carol A, McDonald, Rod, Phare, Susan M, Peters-Golden, Marc, Paine, Robert, III, Toews, Galen B

“…To characterize the role of GM-CSF in pulmonary fibrosis, we have studied bleomycin-induced fibrosis in wild-type mice vs mice with a targeted deletion of the…”
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Granulocyte-Macrophage Colony-Stimulating Factor in the Innate Immune Response to Pneumocystis carinii Pneumonia in Mice by Paine, Robert, III, Preston, Angela M, Wilcoxen, Steven, Jin, Hong, Siu, Brian B, Morris, Susan B, Reed, Jacquelyn A, Ross, Gary, Whitsett, Jeffrey A, Beck, James M

“…Innate immunity plays an important role in pulmonary host defense against Pneumocystis carinii, an important pathogen in individuals with impaired…”
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Localization of 5-lipoxygenase to the nucleus of unstimulated rat basophilic leukemia cells by T G Brock, R Paine, 3rd, M Peters-Golden

“…Arachidonate metabolism by 5-lipoxygenase (5-LO) coincides with the translocation of the enzyme from a soluble to a pelletable fraction in thoroughly disrupted…”
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Cell adhesion molecules and pulmonary fibrosis by Paine, 3rd, R, Ward, P A

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Pneumocystis Pneumonia Increases the Susceptibility of Mice to Sublethal Hyperoxia by BECK, James M, PRESTON, Angela M, WILCOXEN, Steven E, MORRIS, Susan B, WHITE, Eric S, PAINE, Robert III

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Lung volume reduction surgery alters management of pulmonary nodules in patients with severe COPD by Ojo, T C, Martinez, F, Paine, 3rd, R, Christensen, P J, Curtis, J L, Weg, J G, Kazerooni, E A, Whyte, R

“…To examine the role of lung volume reduction surgery (LVRS) in expanding the treatment options for patients with single pulmonary nodules and emphysema…”
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