Search Results - "PAIMELA, Leena"

The treatment of disc herniation-induced sciatica with infliximab : One-year follow-up results of FIRST II, a randomized controlled trial by KORHONEN, Timo, KARPPINEN, Jaro, VEEGER, Nic, HAAPEA, Marianne, TORKKI, Markus, TERVONEN, Osmo, SEITSALO, Seppo, HURRI, Heikki, PAIMELA, Leena, MALMIVAARA, Antti, LINDGREN, Karl-August, BOWMAN, Chris, HAMMOND, Anthony, KIRKHAM, Bruce, JÄRVINEN, Simo, NIINIMÄKI, Jaakko

“…A randomized controlled trial. To evaluate the long-term efficacy of infliximab, a monoclonal antibody against tumor necrosis factor alpha (TNF-alpha), in…”
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Regression of necrotizing scleritis in Wegener’s granulomatosis after infliximab treatment by Kontkanen, Matti, Paimela, Leena, Kaarniranta, Kai

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Tumor necrosis factor-alpha monoclonal antibody, infliximab, used to manage severe sciatica by Karppinen, Jaro, Korhonen, Timo, Malmivaara, Antti, Paimela, Leena, Kyllönen, Eero, Lindgren, Karl-August, Rantanen, Pekka, Tervonen, Osmo, Niinimäki, Jaakko, Seitsalo, Seppo, Hurri, Heikki

“…An open-label study was conducted. To evaluate the efficacy and safety of infliximab, a monoclonal chimeric antibody, against tumor necrosis factor-alpha…”
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The treatment of disc herniation-induced sciatica with infliximab : Results of a randomized, controlled, 3-month follow-up study by KORHONEN, Timo, KARPPINEN, Jaro, PAIMELA, Leena, MALMIVAARA, Antti, LINDGREN, Karl-August, JÄRVINEN, Simo, NIINIMAKI, Jaakko, VEEGER, Nic, SEITSALO, Seppo, HURRI, Heikki

“…A randomized controlled trial. To evaluate the efficacy of infliximab, a monoclonal antibody against tumor necrosis factor (TNF)-alpha in a randomized…”
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Intra-articular glucocorticoid injections should not be neglected in the remission targeted treatment of early rheumatoid arthritis: a post hoc analysis from the NEO-RACo trial by Kuusalo, Laura A, Puolakka, Kari T, Kautiainen, Hannu, Alasaarela, Eeva M, Hannonen, Pekka J, Julkunen, Heikki A, Kaipiainen-Seppänen, Oili A, Korpela, Markku M, Möttönen, Timo T, Paimela, Leena H, Peltomaa, Ritva L, Yli-Kerttula, Timo K, Leirisalo-Repo, Marjatta, Rantalaiho, Vappu M

“…To study the effects of neglecting intra-articular glucocorticoid injections (IAGCIs) into swollen joints in early rheumatoid arthritis (RA). Ninety-nine…”
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Efficacy of infliximab for disc herniation-induced Sciatica: One-year follow-up by KORHONEN, Timo, KARPPINEN, Jaro, HURRI, Heikki, MALMIVAARA, Antti, AUTIO, Reijo, NIINIMÄKI, Jaakko, PAIMELA, Leena, KYLLÖNEN, Eero, LINDGREN, Karl-August, TERVONEN, Osmo, SEITSALO, Seppo

“…An open-label trial. To test the long-term efficacy of infliximab, a monoclonal antibody against tumor necrosis factor-alpha (TNF-alpha), in disc…”
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Efficacy and safety of ustekinumab in patients with active psoriatic arthritis: 1 year results of the phase 3, multicentre, double-blind, placebo-controlled PSUMMIT 1 trial by McInnes, Iain B, Dr, Kavanaugh, Arthur, Prof, Gottlieb, Alice B, MD, Puig, Lluís, MD, Rahman, Proton, MD, Ritchlin, Christopher, MD, Brodmerkel, Carrie, PhD, Li, Shu, PhD, Wang, Yuhua, PhD, Mendelsohn, Alan M, MD, Doyle, Mittie K, MD

“…Summary Background Many patients with psoriasis develop psoriatic arthritis, a chronic inflammatory disease that afflicts peripheral synovial, axial, and…”
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Effect of treatment on the outcome of very early rheumatoid arthritis by Ritva Peltomaa, Leena Paimela, Tapani Helve, Marjatta Leirisalo-Repo

“…Objective: To evaluate the effect of treatment on the outcome of very early RA. Methods: In a 3-year prospective study of 27 patients with very early RA (VERA)…”
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Cervical Spine Involvement among Patients with Rheumatoid Arthritis Treated Actively with Treat-to-target Strategy: 10-year Results of the NEO-RACo Study by Sandström, Tia, Rantalaiho, Vappu, Yli-Kerttula, Timo, Kautiainen, Hannu, Malmi, Timo, Karjalainen, Anna, Uusitalo, Tea, Julkunen, Heikki, Kaipiainen-Seppänen, Oili, Paimela, Leena, Puolakka, Kari, Uutela, Toini, Möttönen, Timo, Hannonen, Pekka, Leirisalo-Repo, Marjatta, Laasonen, Leena, Kauppi, Markku

“…To evaluate the development of radiological changes of the cervical spine in patients with rheumatoid arthritis (RA) in the NEO-RACo trial treated with an…”
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Infliximab for 6 months added on combination therapy in early rheumatoid arthritis: 2-year results from an investigator-initiated, randomised, double-blind, placebo-controlled study (the NEO-RACo Study) by Leirisalo-Repo, Marjatta, Kautiainen, Hannu, Laasonen, Leena, Korpela, Markku, Kauppi, Markku J, Kaipiainen-Seppänen, Oili, Luosujärvi, Riitta, Luukkainen, Reijo, Karjalainen, Anna, Blåfield, Harri, Uutela, Toini, Ilva, Kirsti, Julkunen, Heikki A, Paimela, Leena, Puolakka, Kari, Moilanen, Eeva, Hannonen, Pekka J, Möttönen, Timo

“…Early treatment of patients with rheumatoid arthritis (RA) with combination treatment starting with methotrexate, sulfasalazine, hydroxychloroquine and…”
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Targeted treatment with a combination of traditional DMARDs produces excellent clinical and radiographic long-term outcomes in early rheumatoid arthritis regardless of initial infliximab. The 5-year follow-up results of a randomised clinical trial, the NEO-RACo trial by Rantalaiho, Vappu, Kautiainen, Hannu, Korpela, Markku, Hannonen, Pekka, Kaipiainen-Seppänen, Oili, Möttönen, Timo, Kauppi, Markku, Karjalainen, Anna, Laiho, Kari, Laasonen, Leena, Hakola, Mikko, Peltomaa, Ritva, Leirisalo-Repo, Marjatta

“…To study whether adding initial infliximab to remission-targeted initial combination-DMARD treatment improves the long-term outcomes in patients with early…”
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Causes of death in patients with rheumatoid arthritis from 1971 to 1991 with special reference to autopsy by Koivuniemi, Riitta, Paimela, Leena, Leirisalo-Repo, Marjatta

“…Rheumatoid arthritis (RA) patients have premature mortality, mostly attributed to cardiovascular diseases (CVDs). We studied causes of death (CoDs) and…”
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Double-blind, randomized, placebo-controlled study of three-month treatment with the combination of ofloxacin and roxithromycin in recent-onset reactive arthritis by Kuuliala, Antti, Julkunen, Heikki, Paimela, Leena, Peltomaa, Ritva, Kautiainen, Hannu, Repo, Heikki, Leirisalo-Repo, Marjatta

“…In a randomized, double-blind, placebo-controlled trial, 56 patients with recent-onset ReA [enteroarthritis, n  = 47 (84 %); uroarthritis, n  = 9 (16 %)] were…”
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Work disability in Finnish patients with rheumatoid arthritis: a 15-year follow-up by Tiippana-Kinnunen, Tarja, Paimela, Leena, Peltomaa, Ritva, Kautiainen, Hannu, Laasonen, Leena, Leirisalo-Repo, Marjatta

“…To investigate long-term work disability of patients with early rheumatoid arthritis (RA) and to examine impact of early disease activity and radiological…”
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High burden of adverse events is associated with reduced remission rates in early rheumatoid arthritis by Kuusalo, Laura, Puolakka, Kari, Kautiainen, Hannu, Karjalainen, Anna, Malmi, Timo, Paimela, Leena, Leirisalo-Repo, Marjatta, Rantalaiho, Vappu

“…Adverse events (AEs) are common during disease-modifying antirheumatic drug (DMARD) treatment, but their influence on treatment results is unclear. We studied…”
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Failure in longterm treatment is rare in actively treated patients with rheumatoid arthritis, but may be predicted by high health assessment score at baseline and by residual disease activity at 3 and 6 months: the 5-year followup results of the randomized clinical NEO-RACo trial by Rantalaiho, Vappu, Kautiainen, Hannu, Järvenpää, Salme, Korpela, Markku, Malmi, Timo, Hannonen, Pekka, Kaipiainen-Seppänen, Oili, Yli-Kerttula, Timo, Möttönen, Timo, Mustila, Anu, Karjalainen, Anna, Paimela, Leena, Uutela, Toini, Leirisalo-Repo, Marjatta

“…With modern initial aggressive combination treatments with synthetic disease-modifying antirheumatic drugs (sDMARD), most patients with rheumatoid arthritis…”
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Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: a randomised trial by Möttönen, Timo, Hannonen, Pekka, Leirisalo-Repo, Marjatta, Nissilä, Martti, Kautiainen, Hannu, Korpela, Markku, Laasonen, Leena, Julkunen, Heikki, Luukkainen, Reijo, Vuori, Kaisa, Paimela, Leena, Blåfield, Harri, Hakala, Markku, Ilva, Kirsti, Yli-Kerttula, Urpo, Puolakka, Kari, Järvinen, Pentti, Hakola, Mikko, Piirainen, Heikki, Ahonen, Jari, Pälvimäki, Ilppo, Forsberg, Sinikka, Koota, Kalevi, Friman, Claes

“…The treatment of rheumatoid arthritis should aim at clinical remission. This multicentre, randomised trial with 2-year follow-up sought evidence on the…”
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Functions of polymorphonuclear leukocytes in early rheumatoid arthritis by LEIRISALO-REPO, M, PAIMELA, L, KOSKIMIES, S, REPO, H

“…We carried out a prospective study on clinical variables and functions of polymorphonuclear leukocytes (PMNs) of 20 patients with early rheumatoid arthritis…”
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Amyloidosis is frequently undetected in patients with rheumatoid arthritis by Koivuniemi, Riitta, Paimela, Leena, Suomalainen, Risto, Törnroth, Tom, Leirisalo-Repo, Marjatta

“…Prevalence of AA amyloid in rheumatoid arthritis (RA) is still unclear. The objective of this retrospective study was whether dedicated re-examination of…”
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Amyloidosis as a cause of death in patients with rheumatoid arthritis by KOIVUNIEMI, R, PAIMELA, L, SUOMALAINEN, R, LEIRISALO-REPO, M

“…To study amyloidosis as a cause of death along with associated factors and frequency of pre-mortem diagnosis in patients with rheumatoid arthritis (RA)…”
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