Search Results - "PAGEL, FRANCES T."

Mutations in the GTPase Center of Escherichia coli 23S rRNA Indicate Release Factor 2-Interactive Sites by Xu, Wenbing, Pagel, Frances T, Murgola, Emanuel J

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UGA Suppression by a Mutant RNA of the Large Ribosomal Subunit by Jemiolo, D K, Pagel, F T, Murgola, E J

“…A role for rRNA in peptide chain termination was indicated several years ago by isolation of a 16S rRNA (small subunit) mutant of Escherichia coli that…”
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A Base Substitution in the Amino Acid Acceptor Stem of tRNALys Causes Both Misacylation and Altered Decoding by Pagel, Frances T., Murgola, Emanuel J.

“…In 1984, our laboratory reported the characterization of the first misacylated tRNA missense suppressor, a mutant Escherichia coli lysine tRNA with a C70 to U…”
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Phenotypic heterogeneity of mutational changes at a conserved nucleotide in 16 s ribosomal RNA by Pagel, Frances T, Zhao, Song Q, Hijazi, Kathryn A, Murgola, Emanuel J

“…RNA sites that contain unpaired or mismatched nucleotides can be interaction sites for other macromolecules. C1054, a virtually universally conserved…”
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Variety of nonsense suppressor phenotypes associated with mutational changes at conserved sites in Escherichia coli ribosomal RNA by Murgola, E J, Pagel, F T, Hijazi, K A, Arkov, A L, Xu, W, Zhao, S Q

“…To screen for ribosomal RNA mutants defective in peptide chain termination, we have been looking for rRNA mutants that exhibit different patterns of…”
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A Base Substitution in the Amino Acid Acceptor Stem of tRNALys Causes Both Misacylation and Altered Decoding by PAGEL, FRANCES T., MURGOLA, EMANUEL J.

“…In 1984, our laboratory reported the characterization of the first misacylated tRNA missense suppressor, a mutant Escherichia coli lysine tRNA with a C70 to U…”
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Codon context effects in missense suppression by Murgola, E J, Pagel, F T, Hijazi, K A

“…After our first observation of codon context effects in missense suppression ( Murgola & Pagel , 1983), we measured the suppression of missense mutations at…”
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Missense and nonsense suppressors can correct frameshift mutations by Tucker, S D, Murgola, E J, Pagel, F T

“…Missense and nonsense suppressor tRNAs, selected for their ability to read a new triplet codon, were observed to suppress one or more frameshift mutations in…”
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Doublet translocation at GGA is mediated directly by mutant tRNA(2Gly) by Pagel, F T, Tuohy, T M, Atkins, J F, Murgola, E J

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Codon recognition by glycine transfer RNAs of Escherichia coli in vivo by Murgola, E J, Pagel, F T

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Anticodon Shift in tRNA: A Novel Mechanism in Missense and Nonsense Suppression by Murgola, Emanuel J., Prather, Norman E., Mims, Betsy H., Pagel, Frances T., Hijazi, Kathryn A.

“…In a previous publication, an unusual UGG-reading missense suppressor caused by insertion of an extra adenylate residue in the anticodon loop of an Escherichia…”
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Missense and nonsense suppressors derived from a glycine tRNA by nucleotide insertion and deletion in vivo by Murgola, E J, Prather, N E, Pagel, F T, Mims, B H, Hijazi, K A

“…Beginning with a missense suppressor tRNA and a nonsense suppressor tRNA, both in Escherichia coli and each containing an extra nucleotide in the anticodon…”
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