Search Results - "PADUA, Maria B"

Congenital heart defects caused by FOXJ1 by Padua, Maria B, Helm, Benjamin M, Wells, John R, Smith, Amanda M, Bellchambers, Helen M, Sridhar, Arthi, Ware, Stephanie M

“…Abstract FOXJ1 is expressed in ciliated cells of the airways, testis, oviduct, central nervous system and the embryonic left–right organizer. Ablation or…”
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Single cell RNA analysis of the left–right organizer transcriptome reveals potential novel heterotaxy genes by Bellchambers, Helen M., Phatak, Amruta R., Nenni, Mardi J., Padua, Maria B., Gao, Hongyu, Liu, Yunlong, Ware, Stephanie M.

“…The establishment of left–right patterning in mice occurs at a transient structure called the embryonic node or left–right organizer (LRO). Previous analysis…”
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Combined Loss of the GATA4 and GATA6 Transcription Factors in Male Mice Disrupts Testicular Development and Confers Adrenal-Like Function in the Testes by Padua, Maria B, Jiang, Tianyu, Morse, Deborah A, Fox, Shawna C, Hatch, Heather M, Tevosian, Sergei G

“…The roles of the GATA4 and GATA6 transcription factors in testis development were examined by simultaneously ablating Gata4 and Gata6 with Sf1Cre (Nr5a1Cre)…”
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The transcription factor GATA4 is required for follicular development and normal ovarian function by Efimenko, Evgeni, Padua, Maria B., Manuylov, Nikolay L., Fox, Shawna C., Morse, Deborah A., Tevosian, Sergei G.

“…Sex determination in mammals requires interaction between the transcription factor GATA4 and its cofactor FOG2. We have recently described the function of both…”
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Dependence receptor UNC5A restricts luminal to basal breast cancer plasticity and metastasis by Padua, Maria B, Bhat-Nakshatri, Poornima, Anjanappa, Manjushree, Prasad, Mayuri S, Hao, Yangyang, Rao, Xi, Liu, Sheng, Wan, Jun, Liu, Yunlong, McElyea, Kyle, Jacobsen, Max, Sandusky, George, Althouse, Sandra, Perkins, Susan, Nakshatri, Harikrishna

“…The majority of estrogen receptor-positive (ERα ) breast cancers respond to endocrine therapies. However, resistance to endocrine therapies is common in 30% of…”
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Evolution and Function of the Uterine Serpins (SERPINA14) by Padua, Maria B., Hansen, Peter J.

“…Citation Padua MB, Hansen PJ. Evolution and function of the uterine serpins (SERPINA14). Am J Reprod Immunol 2010 Uterine serpins (recently designated as…”
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Changes in expression of cell-cycle-related genes in PC-3 prostate cancer cells caused by ovine uterine serpin by Padua, Maria B., Hansen, Peter J.

“…The hormonal‐regulated serpin, ovine uterine serpin (OvUS), also called uterine milk protein (UTMP), inhibits proliferation of lymphocytes and prostate cancer…”
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Simultaneous Gene Deletion of Gata4 and Gata6 Leads to Early Disruption of Follicular Development and Germ Cell Loss in the Murine Ovary1 by Padua, Maria B, Fox, Shawna C, Jiang, Tianyu, Morse, Deborah A, Tevosian, Sergei G

“…Granulosa cell formation and subsequent follicular assembly are important for ovarian development and function. Two members of the GATA family of transcription…”
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The genetic landscape of cardiovascular left–right patterning defects by Wells, John R, Padua, Maria B, Ware, Stephanie M

“…Heterotaxy is a disorder with complex congenital heart defects and diverse left–right (LR) patterning defects in other organ systems. Despite evidence…”
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ACP5 (Uteroferrin): Phylogeny of an Ancient and Conserved Gene Expressed in the Endometrium of Mammals1 by Padua, Maria B, Lynch, Vincent J, Alvarez, Natalia V, Garthwaite, Mark A, Golos, Thaddeus G, Bazer, Fuller W, Kalkunte, Satyan, Sharma, Surendra, Wagner, Gunter P, Hansen, Peter J

“…Type 5 acid phosphatase (ACP5; also known as tartrate-resistant acid phosphatase or uteroferrin) is a metalloprotein secreted by the endometrial glandular…”
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Simultaneous gene deletion of gata4 and gata6 leads to early disruption of follicular development and germ cell loss in the murine ovary by Padua, Maria B, Fox, Shawna C, Jiang, Tianyu, Morse, Deborah A, Tevosian, Sergei G

“…Granulosa cell formation and subsequent follicular assembly are important for ovarian development and function. Two members of the GATA family of transcription…”
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Adrenal Development in Mice Requires GATA4 and GATA6 Transcription Factors by Tevosian, Sergei G, Jiménez, Elizabeth, Hatch, Heather M, Jiang, Tianyu, Morse, Deborah A, Fox, Shawna C, Padua, Maria B

“…The adrenal glands consist of an outer cortex and an inner medulla, and their primary purposes include hormone synthesis and secretion. The adrenal cortex…”
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Pharmacological Dual Inhibition of Tumor and Tumor-Induced Functional Limitations in a Transgenic Model of Breast Cancer by Wang, Ruizhong, Bhat-Nakshatri, Poornima, Padua, Maria B, Prasad, Mayuri S, Anjanappa, Manjushree, Jacobson, Max, Finnearty, Courtney, Sefcsik, Victoria, McElyea, Kyle, Redmond, Rachael, Sandusky, George, Penthala, Narsimha, Crooks, Peter A, Liu, Jianguo, Zimmers, Teresa, Nakshatri, Harikrishna

“…Breast cancer progression is associated with systemic effects, including functional limitations and sarcopenia without the appearance of overt cachexia…”
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Non-coding cause of congenital heart defects: Abnormal RNA splicing with multiple isoforms as a mechanism for heterotaxy by Wells, John R., Padua, Maria B., Haaning, Allison M., Smith, Amanda M., Morris, Shaine A., Tariq, Muhammad, Ware, Stephanie M.

“…Heterotaxy is a disorder characterized by severe congenital heart defects (CHDs) and abnormal left-right patterning in other thoracic or abdominal organs…”
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ACP5 (Uteroferrin): Phylogeny of an Ancient and Conserved Gene Expressed in the Endometrium of Mammals by PADUA, Maria B, LYNCH, Vincent J, ALVAREZ, Natalia V, GARTHWAITE, Mark A, GOLOS, Thaddeus G, BAZER, Fuller W, KALKUNTE, Satyan, SHARMA, Surendra, WAGNER, Gunter P, HANSEN, Peter J

“…Type 5 acid phosphatase (ACP5; also known as tartrate-resistant acid phosphatase or uteroferrin) is a metalloprotein secreted by the endometrial glandular…”
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molecular phylogeny of uterine serpins and its relationship to evolution of placentation by Padua, Maria B, Kowalski, Andrés A, Cañas, Miryan Y, Hansen, Peter J

“…Uterine serpins (USs), designated as SERPINA14, are expressed in the endometrium in response to progesterone. All species identified as having USs exhibit…”
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Actions of progesterone on uterine immunosuppression and endometrial gland development in the uterine gland knockout (UGKO) ewe by Padua, Maria B., Tekin, Şaban, Spencer, Thomas E., Hansen, Peter J.

“…In ewes, the uterine gland knockout (UGKO) phenotype is caused by neonatal exposure to norgestomet to arrest uterine gland development and produce an adult…”
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Regulation of DNA synthesis and the cell cycle in human prostate cancer cells and lymphocytes by ovine uterine serpin by Padua, Maria B, Hansen, Peter J

“…Uterine serpins are members of the serine proteinase inhibitor superfamily. Like some other serpins, these proteins do not appear to be functional proteinase…”
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Expression and properties of recombinant ovine uterine serpin by Tekin, Saban, Padua, Maria B, Brad, Amber M, Rhodes, Michelle L, Hansen, Peter J

“…Ovine uterine serpin (OvUS) is produced in the uterus of sheep under the influence of progesterone. It weakly inhibits pepsin and reduces proliferation of…”
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Identification and cloning of caprine uterine serpin by Tekin, Şaban, Padua, Maria B., Newton, Gary R., Hansen, Peter J.

“…The uterine serpins have been described in sheep, cattle, and pigs as a highly diverged group of the large superfamily of serpin proteins that typically…”
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