Search Results - "PADMAJA MUMMANENI"
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Epigenetics and Oncology
Published in Pharmacotherapy (01-05-2014)“…Epigenetic modifications play a critical role in the development of pediatric and adult cancers, contributing to the cumulative changes observed as normal…”
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Meta-analysis of microarray data using a pathway-based approach identifies a 37-gene expression signature for systemic lupus erythematosus in human peripheral blood mononuclear cells
Published in BMC medicine (30-05-2011)“…A number of publications have reported the use of microarray technology to identify gene expression signatures to infer mechanisms and pathways associated with…”
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Pharmacogenomic Biomarker Information in Drug Labels Approved by the United States Food and Drug Administration: Prevalence of Related Drug Use
Published in Pharmacotherapy (01-08-2008)“…Study Objectives. To review the labels of United States Food and Drug Administration (FDA)‐approved drugs to identify those that contain pharmacogenomic…”
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Characterization of the Saccharomyces cerevisiae Homolog of the Melatonin Rhythm Enzyme Arylalkylamine N-Acetyltransferase (EC 2.3.1.87)
Published in The Journal of biological chemistry (14-12-2001)“…Arylalkylamine N-acetyltransferase (AANAT, serotonin N-acetyltransferase, EC 2.3.1.87) plays a unique transduction role in vertebrate physiology by converting…”
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Sex differences and genomics in autoimmune diseases
Published in Journal of autoimmunity (01-05-2012)“…Abstract Autoimmune diseases (AIDs) are believed to be multifactorial diseases that commonly involve multiple organ systems. About three fourth of the patients…”
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Tandem B1 Elements Located in a Mouse Methylation Center Provide a Target for de Novo DNA Methylation
Published in The Journal of biological chemistry (17-12-1999)“…A cis-acting methylation center that signals de novo DNA methylation is located upstream of the mouse Aprt gene. In the current study, two approaches were…”
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Epigenetic Gene Inactivation Induced by a Cis-acting Methylation Center (∗)
Published in The Journal of biological chemistry (13-01-1995)“…In this report we test the hypothesis that a cis-acting methylation center can induce epigenetic gene inactivation. The cis-acting element used is an 838-base…”
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A cis-acting element accounts for a conserved methylation pattern upstream of the mouse adenine phosphoribosyltransferase gene
Published in The Journal of biological chemistry (05-01-1993)“…A 2.1-kilobase pair region located just upstream of the mouse aprt (adenine phosphoribosyltransferase) gene has a methylation pattern that is conserved in…”
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Sex differences and genomics in autoimmune diseases: Gender, Sex Hormones, Pregnancy and Autoimmunity
Published in Journal of autoimmunity (2012)Get full text
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Allopurinol pharmacogenetics: assessment of potential clinical usefulness
Published in Pharmacogenomics (01-12-2011)“…Use of pharmacogenetics to inform treatment decisions remains a priority for clinicians, patients and public health agencies. We previously developed a…”
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Region- and cell type-specific de novo DNA methylation in cultured mammalian cells
Published in Somatic cell and molecular genetics (01-03-1991)“…A region upstream of the mouse adenine phosphoribosyltransferase (aprt) gene has a well characterized methylation pattern for HpaII/MspI sites. When an…”
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The primary function of a redundant Sp1 binding site in the mouse aprt gene promoter is to block epigenetic gene inactivation
Published in Nucleic acids research (15-11-1998)“…The promoter region of the mouse adenine phosphoribosyltransferase (aprt) gene contains one nonconsensus Sp1 binding site at its 5′ end followed by three…”
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