Search Results - "PADGETT, R. W"
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Pioneer Axon Guidance by UNC-129, a C. elegans TGF-β
Published in Science (American Association for the Advancement of Science) (31-07-1998)“…The unc-129 gene, like the unc-6 netrin gene, is required to guide pioneer motoraxons along the dorsoventral axis of Caenorhabditis elegans. unc-129 encodes a…”
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Human BMP Sequences Can Confer Normal Dorsal-Ventral Patterning in the Drosophila Embryo
Published in Proceedings of the National Academy of Sciences - PNAS (01-04-1993)“…The type β transforming growth factor family is composed of a series of processed, secreted growth factors, several of which have been implicated in important…”
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3
Mammalian Dwarfins are Phosphorylated in Response to Transforming Growth Factor β and are Implicated in Control of Cell Growth
Published in Proceedings of the National Academy of Sciences - PNAS (20-08-1996)“…The dwarfin protein family has been genetically implicated in transforming growth factor β (TGF-β )-like signaling pathways in Drosophila and Caenorhabditis…”
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TGFβ-related pathways: roles in Caenorhabditis elegans development
Published in Trends in Genetics (2000)“…Genetic and molecular analysis in Caenorhabditis elegans has produced new insights into how TGFβ-related pathways transduce signals and the developmental…”
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5
Molecular organization of the decapentaplegic gene in Drosophila melanogaster
Published in Genes & development (01-07-1990)“…The decapentaplegic (dpp) locus of Drosophila melanogaster is a greater than 55 kb genetic unit required for proper pattern formation during the embryonic and…”
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The sequence of a large L1Md element reveals a tandemly repeated 5' end and several features found in retrotransposons
Published in Molecular and Cellular Biology (01-01-1986)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor- β family
Published in Nature (London) (01-01-1987)“…The decapentaplegic gene complex (DPP-C) has been implicated in several events in pattern formation during Drosophila development. During embryogenesis, the…”
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Cross regulation of decapentaplegic and Ultrabithorax transcription in the embryonic visceral mesoderm of Drosophila
Published in Development (Cambridge) (01-04-1993)“…The Drosophila decapentaplegic gene (dpp) encodes a TGF-beta family member involved in signal transduction during embryonic midgut formation. The shortvein…”
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tolkin gene is a tolloid/BMP-1 homologue that is essential for Drosophila development
Published in Genetics (Austin) (01-09-1995)“…The Drosophila decapentaplegic (dpp) gene, a member of the transforming growth factor beta superfamily of growth factors, is critical for specification of the…”
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Caenorhabditis elegans Genes sma-2, sma-3, and sma-4 Define a Conserved Family of Transforming Growth Factor β Pathway Components
Published in Proceedings of the National Academy of Sciences - PNAS (23-01-1996)“…Although transforming growth factor β (TGF-β ) superfamily ligands play critical roles in diverse developmental processes, how cells transduce signals from…”
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Transforming growth factor β signaling mediators and modulators
Published in Gene (16-05-2000)“…Transforming growth factor β is a multi-functional growth and differentiation factor responsible for regulating many diverse biological processes in both…”
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Book Review Journal Article -
12
Mutational analysis of the Drosophila tolloid gene, a human BMP-1 homolog
Published in Development (Cambridge) (01-04-1994)“…Seven zygotically active genes have been identified in Drosophila that determine the fate of dorsal cells in the developing embryo. decapentaplegic (dpp), a…”
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Molecular evolution at the decapentaplegic locus in Drosophila
Published in Genetics (Austin) (01-02-1997)“…Using an elaborate set of cis-regulatory sequences, the decapentaplegic (dpp) gene displays a dynamic pattern of gene expression during development. The…”
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Nomenclature: vertebrate mediators of TGFbeta family signals
Published in Cell (18-10-1996)Get full text
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Specificity of TGFβ signaling is conferred by distinct type I receptors and their associated SMAD proteins in Caenorhabditis elegans
Published in Development (Cambridge) (01-01-1999)“…ABSTRACT In C. elegans, the TGFβ-like type II receptor daf-4 is required for two distinct signaling pathways. In association with the type I receptor daf-1, it…”
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A BMP homolog acts as a dose-dependent regulator of body size and male tail patterning in Caenorhabditis elegans
Published in Development (Cambridge) (01-01-1999)“…We cloned the dbl-1 gene, a C. elegans homolog of Drosophila decapentaplegic and vertebrate BMP genes. Loss-of-function mutations in dbl-1 cause markedly…”
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TGF-β signaling, Smads, and tumor suppressors
Published in BioEssays (01-05-1998)“…The transforming growth factor‐β (TGF‐β) superfamily is used throughout animal development for regulating the growth and patterning of many tissue types…”
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18
Insulin worms its way into the spotlight
Published in Genes & development (01-04-2003)“…Insulin has been an important target of investigation for decades, as indicated by its sequence determination by Sanger and colleagues in 1955, and is now the…”
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The TGF-beta signaling pathway is essential for Drosophila oogenesis
Published in Development (Cambridge) (01-05-1996)“…We examine roles of signaling by secreted ligands of the TGF-beta family during Drosophila oogenesis. One family member, the DPP ligand encoded by the…”
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lon-1 Regulates Caenorhabditis elegans Body Size Downstream of the dbl-1 TGFβ Signaling Pathway
Published in Developmental biology (15-06-2002)“…In Caenorhabditis elegans, two well-characterized TGFβ signaling cascades have been identified: the Small/Male tail abnormal (Sma/Mab) and Dauer formation…”
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