Search Results - "PACKHAM, A"

Type X Toxoplasma gondii in a wild mussel and terrestrial carnivores from coastal California: New linkages between terrestrial mammals, runoff and toxoplasmosis of sea otters by Miller, M.A., Miller, W.A., Conrad, P.A., James, E.R., Melli, A.C., Leutenegger, C.M., Dabritz, H.A., Packham, A.E., Paradies, D., Harris, M., Ames, J., Jessup, D.A., Worcester, K., Grigg, M.E.

“…Sea otters in California are commonly infected with Toxoplasma gondii. A unique Type X strain is responsible for 72% of otter infections, but its prevalence in…”
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Physical Interaction between TBX5 and MEF2C Is Required for Early Heart Development by Ghosh, Tushar K., Song, Fei Fei, Packham, Elizabeth A., Buxton, Sarah, Robinson, Thelma E., Ronksley, Jonathan, Self, Tim, Bonser, Andrew J., Brook, J. David

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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T-box genes in human disorders by Packham, Elizabeth A., Brook, J. David

“…The T-box gene family encodes a large family of transcription factors with more than 20 members identified in humans so far, and homologues in many other…”
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Toxoplasma gondii seroprevalence and association with equine protozoal myeloencephalitis: A case–control study of Californian horses by James, K.E., Smith, W.A., Packham, A.E., Conrad, P.A., Pusterla, N.

“…•A relationship between T. gondii serum titers and neurologic signs compatible with EPM was proposed.•No relationship between Sarcocystis neurona and/or…”
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Methods to produce and safely work with large numbers of Toxoplasma gondii oocysts and bradyzoite cysts by Fritz, H., Barr, B., Packham, A., Melli, A., Conrad, P.A.

“…Two major obstacles to conducting studies with Toxoplasma gondii oocysts are the difficulty in reliably producing large numbers of this life stage and safety…”
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Mutation in myosin heavy chain 6 causes atrial septal defect by Brook, J David, Ching, Yung-Hao, Ghosh, Tushar K, Cross, Steve J, Packham, Elizabeth A, Honeyman, Louise, Loughna, Siobhan, Robinson, Thelma E, Dearlove, Andrew M, Ribas, Gloria, Bonser, Andrew J, Thomas, Neil R, Scotter, Andrew J, Caves, Leo S D, Tyrrell, Graham P, Newbury-Ecob, Ruth A, Munnich, Arnold, Bonnet, Damien

“…Atrial septal defect is one of the most common forms of congenital heart malformation. We identified a new locus linked with atrial septal defect on chromosome…”
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Coastal freshwater runoff is a risk factor for Toxoplasma gondii infection of southern sea otters (Enhydra lutris nereis) by MILLER, M. A, GARDNER, I. A, CONRAD, P. A, KREUDER, C, PARADIES, D. M, WORCESTER, K. R, JESSUP, D. A, DODD, E, HARRIS, M. D, AMES, J. A, PACKHAM, A. E

“…The association among anthropogenic environmental disturbance, pathogen pollution and the emergence of infectious diseases in wildlife has been postulated, but…”
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Young steady-state rabbit platelets do not have an enhanced capacity to expose procoagulant phosphatidylserine by Reddy, Emily C., Wang, Hong, Bang, K.W. Annie, Packham, Marian A., Rand, Margaret L.

“…Platelets are recognized to be physiologically and functionally heterogeneous. An example of the diversity in reactivity is the formation of a distinct…”
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Endogenous Transplacental Transmission of Neospora hughesi in Naturally Infected Horses by Pusterla, N, Conrad, P. A, Packham, A. E, Mapes, S. M, Finno, C. J, Gardner, I. A, Barr, B. C, Ferraro, G. L, Wilson, W. D

“…Over a 2-yr study period, we investigated possible endogenous transplacental transmission of Neospora hughesi in 74 mare and foal pairs following the diagnosis…”
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Evaluation of the kinetics of antibodies against Sarcocystis neurona in serum from seropositive healthy horses without neurological deficits treated with ponazuril paste by Pusterla, N., Packham, A., Wilson, W. D., White, A., Bellamy, P., Renier, A. C., Conrad, P. A.

“…Differences in titres against S neurona (magnitude and duration of measureable antibodies) among the two seropositive horse groups were calculated using the…”
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Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome by GHOSH, Tushar K, PACKHAM, Elizabeth A, BONSER, Andrew J, ROBINSON, Thelma E, CROSS, Stephen J, BROOK, J. David

“…Holt-Oram syndrome is caused by mutations in TBX5, a member of the T-box gene family. In order to identify DNA sequences to which the TBX5 protein binds, we…”
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Role of platelets in thrombosis and hemostasis by Packham, M A

“…Platelet aggregates, stabilized by fibrin, rapidly form hemostatic plugs when blood vessels are severed or arterial thrombi at sites of vessel injury, such as…”
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Calpain inhibition by calpeptin does not prevent APLT activity reduction in PS-exposing platelets, but calpeptin has independent pro-apoptotic effects by Gwozdz, Adam M, Leung, Roland, Wang, Hong, Bang, K W Annie, Packham, Marian A, Freedman, John, Rand, Margaret L

“…Exposure of procoagulant phosphatidylserine (PS) on the surface of activated platelets is not readily reversible and this may propagate thrombosis. Persistence…”
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Platelet function assays by Rand, Margaret L., Leung, Roland, Packham, Marian A.

“…The roles of platelets in hemostasis and arterial thrombosis involve their adherence to sites of vessel injury or ruptured atherosclerotic plaques, aggregation…”
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Immune responses in pregnant cattle and bovine fetuses following experimental infection with Neospora caninum by ANDRIANARIVO, A. G, BARR, B. C, ANDERSON, M. L, ROWE, J. D, PACKHAM, A. E, SVERLOW, K. W, CONRAD, P. A

“…Humoral and cell-mediated immune (CMI) responses [i.e. proliferative responses and gamma interferon (IFN-gamma) production], were elicited in five cows…”
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A POLYGEN-adjuvanted killed Neospora caninum tachyzoite preparation failed to prevent foetal infection in pregnant cattle following i.v./i.m. experimental tachyzoite challenge by ANDRIANARIVO, A. G, ROWE, J. D, BARR, B. C, ANDERSON, M. L, PACKHAM, A. E, SVERLOW, K. W, CHOROMANSKI, L, LOUI, C, GRACE, A, CONRAD, P. A

“…Cattle immunised with a POLYGEN-adjuvanted killed Neospora caninum tachyzoite preparation were previously shown to produce interferon (IFN)-gamma at levels…”
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Novel and Canine Genotypes of Giardia duodenalis in Harbor Seals (Phoca vitulina richardsi) by Gaydos, J. K, Miller, W. A, Johnson, C, Zornetzer, H, Melli, A, Packham, A, Jeffries, S. J, Lance, M. M, Conrad, P. A

“…Feces of harbor seals (Phoca vitulina richardsi) and hybrid Glaucous-winged/Western gulls (Larus glaucescens/ occidentalis) from Washington State's inland…”
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Persistence of phosphatidylserine exposure on activated platelets in vivo in rabbits by Rand, Margaret L, Wang, Hong, Bang, K W Annie, Packham, Marian A, Freedman, John

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Description of a new Neospora species (Protozoa: Apicomplexa: Sarcocystidae) by Marsh, A.E, Barr, B.C, Packham, A.E, Conrad, P.A

“…Neospora hughesi n. sp. was isolated from the central nervous system tissue of an adult equine (Equus caballus) from California. The tachyzoites are…”
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Isolation and Characterization of Two Parasitic Protozoa from a Pacific Harbor Seal (Phoca Vitulina Richardsi) With Meningoencephalomyelitis by Miller, Melissa A, Sverlow, Karen, Crosbie, Paul R, Barr, Bradd C, Lowenstine, Linda J, Gulland, Frances M, Packham, Andrea, Conrad, Patricia A

“…Two species of protozoans were isolated from a harbor seal with fatal meninogoencephalitis. Serologic reactivity was detected to both Sarcocystis neurona and…”
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