Search Results - "PACCHIONE, S. J"
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Detection of integration of plasmid DNA into host genomic DNA following intramuscular injection and electroporation
Published in Gene therapy (01-04-2004)“…Plasmid vectors have been widely used for DNA vaccines and gene therapy. Following intramuscular injection, the plasmid that persists is extrachromosomal and…”
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Tumorigenicity assessments of Per.C6 cells and of an Ad5-vectored HIV-1 vaccine produced on this continuous cell line
Published in Developments in biologicals (2006)“…PER.C6, a cell line derived from human embryonic retinal cells transformed with the Adenovirus Type 5 (Ad5) E1A and E1B genes, is used to produce E1-deleted…”
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Journal Article -
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Plasmid DNA vaccines: tissue distribution and effects of DNA sequence, adjuvants and delivery method on integration into host DNA
Published in Intervirology (2000)“…A variety of factors could affect the frequency of integration of plasmid DNA vaccines into host cellular DNA, including DNA sequences within the plasmid, the…”
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Femtosecond laser: a new intradermal DNA delivery method for efficient, long-term gene expression and genetic immunization
Published in The FASEB journal (01-11-2007)“…A femtosecond laser beam gene transduction (SG-LBGT) system is described as a novel and efficient method of intradermal (i.d.) nonviral gene delivery in mice…”
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Journal Article