Search Results - "P. Pinheiro, Daniel"

Synthesis, structural characterization, and cytotoxic evaluation of chalcone derivatives by N. Bandeira, Paulo, L. G. Lemos, Telma, S. Santos, Hélcio, C. S. de Carvalho, Mylena, P. Pinheiro, Daniel, O. de Moraes Filho, Manoel, Pessoa, Cláudia, W. A. Barros-Nepomuceno, Francisco, H. S. Rodrigues, Tigressa, R. V. Ribeiro, Paulo, S. Magalhães, Herbert, M. R. Teixeira, Alexandre

“…Chalcones containing amino or acetamide groups on ring A and electron donating/withdrawing groups on ring B have been shown to have great cytotoxic potential…”
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Starch-based magnetic nanocomposite for targeted delivery of hydrophilic bioactives as anticancer strategy by Sousa, Alexandre C.C., Romo, Adolfo I.B., Almeida, Raimundo R., Silva, Aiêrta C.C., Fechine, Lillian M.U., Brito, Débora H.A., Freire, Rafael M., Pinheiro, Daniel P., Silva, Larissa M.R., Pessoa, Otília D.L., Denardin, Juliano C., Pessoa, Claudia, Ricardo, Nágila M.P.S.

“…[Display omitted] •Starch-based magnetic nanocapsules were successfully synthesized for drug delivery.•A core-shell morphology was obtained, with an average…”
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Synthesis of quinone imine and sulphur-containing compounds with antitumor and trypanocidal activities: redox and biological implications by Almeida, Renata G, Valença, Wagner O, Rosa, Luísa G, de Simone, Carlos A, de Castro, Solange L, Barbosa, Juliana M. C, Pinheiro, Daniel P, Paier, Carlos R. K, de Carvalho, Guilherme G. C, Pessoa, Claudia, Goulart, Marilia O. F, Kharma, Ammar, da Silva Júnior, Eufrânio N

“…Ortho -Quinones represent a special class of redox active compounds associated with a spectrum of pronounced biological activities, including selective…”
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Synthesis of dehydro-α-lapachones, α- and β-lapachones, and screening against cancer cell lines by Moreira, Caroline dos S., Nicoletti, Caroline D., Pinheiro, Daniel P., de Moraes, Leonardo G. C., Futuro, Debora O., Ferreira, Vitor F., Pessoa, Claudia do Ó, da Rocha, David R.

“…14 new naphthoquinones were prepared and tested against human cancer cell lines PC-3 (prostate), HCT-116 (colon carcinoma), SNB-19 (glioblastoma), HL-60…”
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Structural and spectroscopic analysis and evaluation of cytotoxic activity of 2-hydroxychalcones against human cancer cell lines by Leal, Antonio L.A.B., Pinheiro, Daniel P., Barros-Nepomuceno, Francisco W.A., da Silva, Priscila T., Pessoa, Claudia, Almeida-Neto, Francisco W.Q., Marinho, Emmanuel S., Barreto, Antônio C.H., Julião, Murilo S.S., de Paiva, Aldeneide S., Bandeira, Paulo N., de Lima-Neto, Pedro, dos Santos, Hélcio S., Teixeira, Alexandre M.R.

“…•Four chalcones were synthesized by Claisen-Schmidt condensation reaction.•DFT calculations presented a good agreement with the experimental…”
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Lapachol-loaded triblock copoly(oxyalkylene)s micelles: Potential use for anticancer treatment by Lopes, Karen P.S., Pinheiro, Daniel P., Neto, João F.C., Gonçalves, Tamara A., Pereira, Stefano A., Pessoa, Claudia, Vieira, Icaro G.P., Ribeiro, Maria Elenir N.P., Yeates, Stephen G., Ricardo, Nágila M.P.S.

“…[Display omitted] •Poor solubility of drugs is one of the adversities faced for its therapeutic use.•Micelles has been showing efficiency to assist in the…”
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Relationship between Electrochemical Parameters, Cytotoxicity Data against Cancer Cells of 3-Thio-Substituted Nor-Beta-Lapachone Derivatives. Implications for Cancer Therapy by de Paiva, Yen, Silva, Thaissa, Xavier, André, Cardoso, Mariana, da Silva, Fernando, Silva, Maria, Pinheiro, Daniel, Pessoa, Claudia, Ferreira, Vitor, Goulart, Marilia

“…Electrochemical methods are powerful in the characterization and design of redox-modulating agents. We, herein, report the electrochemical investigation, in…”
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Liposomes containing 3-arylamino-nor-β-lapachone derivative: Development, characterization, and in vitro evaluation of the cytotoxic activity by Rebouças, Luciana V., Oliveira, Fátima C.E., Pinheiro, Daniel P., Silva, Maria Francilene S., Ferreira, Vanessa Pinheiro G., Nicolete, Roberto, Oliveira, Augusto C.A., Almeida, Renata G., da Silva Júnior, Eufrânio N., Rizzo, Marcia S., Costa, Marcília P., Zocolo, Guilherme, Ribeiro, Fábio O.S., da Silva, Durcilene A., Pessoa, Claudia

“…This study aimed to encapsulate the novel synthetic naphthoquinone ENSJ39 in liposomes, characterize them, and evaluate their in vitro cytotoxic activity in…”
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Synthesis of quinone imine and sulphur-containing compounds with antitumor and trypanocidal activities: redox and biological implications† †Electronic supplementary information (ESI) available. CCDC 1928261, 1928296, 1928326, 1928361, 1928382 and 1928407. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/d0md00072h by Almeida, Renata G., Valença, Wagner O., Rosa, Luísa G., de Simone, Carlos A., de Castro, Solange L., Barbosa, Juliana M. C., Pinheiro, Daniel P., Paier, Carlos R. K., de Carvalho, Guilherme G. C., Pessoa, Claudia, Goulart, Marilia O. F., Kharma, Ammar, da Silva Júnior, Eufrânio N.

“…New quinoidal compounds were prepared and evaluated against T. cruzi and cancer cell lines for the identification of new bioactive agents. Ortho -Quinones…”
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Flagellar proteins prediction after sequence-structure alignments of coronin and Arp2/3 complex in Leishmania spp by Costa, M.P., Ribeiro, H.L., Pacheco, A.C.L., Pinheiro, D.P., Kamimura, M.T., Araujo-Filho, R., de Oliveira, D.M.

“…Leishmania are uniflagellate protozoa, whose flagellum plays a key role in motility, being essential for parasite migration, invasion and persistence on host…”
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