Search Results - "P. Ogrodzinski, Martin"
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Counterion Tuning of Near-Infrared Organic Salts Dictates Phototoxicity to Inhibit Tumor Growth
Published in ACS applied materials & interfaces (07-12-2022)“…Photodynamic therapy (PDT) has the potential to improve cancer treatment by providing dual selectivity through the use of both photoactive agent and light,…”
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Sialic Acid Metabolism: A Key Player in Breast Cancer Metastasis Revealed by Metabolomics
Published in Frontiers in oncology (28-05-2018)“…Metastatic breast cancer is currently incurable. It has recently emerged that different metabolic pathways support metastatic breast cancer. To further uncover…”
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Integrated analyses of murine breast cancer models reveal critical parallels with human disease
Published in Nature communications (22-07-2019)“…Mouse models have an essential role in cancer research, yet little is known about how various models resemble human cancer at a genomic level. Here, we…”
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Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells
Published in Cancer & metabolism (30-12-2019)“…Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with limited treatment options. Pyruvate kinase, especially the M2 isoform (PKM2), is highly…”
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UDP-glucose 6-dehydrogenase knockout impairs migration and decreases in vivo metastatic ability of breast cancer cells
Published in Cancer letters (01-11-2020)“…Dysregulated metabolism is a hallmark of cancer that supports tumor growth and metastasis. One understudied aspect of cancer metabolism is altered nucleotide…”
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Targeting Subtype-Specific Metabolic Preferences in Nucleotide Biosynthesis Inhibits Tumor Growth in a Breast Cancer Model
Published in Cancer research (Chicago, Ill.) (15-01-2021)“…Investigating metabolic rewiring in cancer can lead to the discovery of new treatment strategies for breast cancer subtypes that currently lack targeted…”
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Deciphering metabolic rewiring in breast cancer subtypes
Published in Translational research : the journal of laboratory and clinical medicine (01-11-2017)“…Metabolic reprogramming, an emerging hallmark of cancer, is observed in breast cancer. Breast cancer cells rewire their cellular metabolism to meet the demands…”
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Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas
Published in Science translational medicine (06-10-2021)“…Childhood posterior fossa group A ependymomas (PFAs) have limited treatment options and bear dismal prognoses compared to group B ependymomas (PFBs). PFAs…”
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Metabolomic profiling of mouse mammary tumor-derived cell lines reveals targeted therapy options for cancer subtypes
Published in Cellular oncology (Dordrecht) (01-12-2020)“…Purpose Breast cancer is a heterogeneous disease with several subtypes that currently do not have targeted therapeutic options. Metabolomics has the potential…”
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Measuring the Nutrient Metabolism of Adherent Cells in Culture
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Metabolite extraction from cells cultured in vitro enables the comprehensive measurement of intracellular metabolites. These extracts can be analyzed using…”
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Metformin induces distinct bioenergetic and metabolic profiles in sensitive versus resistant high grade serous ovarian cancer and normal fallopian tube secretory epithelial cells
Published in Oncotarget (09-01-2018)“…Metformin is a widely used agent for the treatment of diabetes and infertility, however, it has been found to have anti-cancer effects in a variety of…”
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LEMIERRE SYNDROME DUE TO SUPERIMPOSED FUSOBACTERIUM SPECIES INFECTION LEADING TO SEPTIC PULMONARY EMBOLISM AND RESPIRATORY FAILURE
Published in Chest (01-10-2023)Get full text
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LUNG VISCERAL CRISIS LEADING TO ACUTE HYPOXIC RESPIRATORY FAILURE IN A MALE PATIENT WITH METASTATIC BREAST CANCER
Published in Chest (01-10-2023)Get full text
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NEGATIVE-PRESSURE PULMONARY EDEMA IN A PATIENT WITH LEFT VOCAL CORD HYPOMOBILITY AND MUCUS PLUGGING
Published in Chest (01-10-2023)Get full text
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CANDIDA DUBLINIENSIS EMPYEMA IN AN IMMUNOCOMPETENT PATIENT AS A DELAYED PRESENTATION OF AN UNIDENTIFIED ESOPHAGEAL SURGERY COMPLICATION
Published in Chest (01-10-2023)Get full text
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MDB-78. ISOCITRATE DEHYDROGENASE 1 INHIBITION PRIMES GROUP-3 MEDULLOBLASTOMAS FOR CUPROPTOSIS
Published in Neuro-oncology (Charlottesville, Va.) (18-06-2024)Get full text
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