Search Results - "P. Michailova"

Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approaches by Hohendanner, Felix, McCulloch, Andrew D, Blatter, Lothar A, Michailova, Anushka P

“…Calcium plays a crucial role in excitation-contraction coupling (ECC), but it is also a pivotal second messenger activating Ca(2+)-dependent transcription…”
Get full text

Molecular and Subcellular-Scale Modeling of Nucleotide Diffusion in the Cardiac Myofilament Lattice by Kekenes-Huskey, Peter M., Liao, Tao, Gillette, Andrew K., Hake, Johan E., Zhang, Yongjie, Michailova, Anushka P., McCulloch, Andrew D., McCammon, J. Andrew

“…Contractile function of cardiac cells is driven by the sliding displacement of myofilaments powered by the cycling myosin crossbridges. Critical to this…”
Get full text

Cytogenetic index and functional genome alterations in Chironomus piger Strenzke (Diptera, Chironomidae) in the assessment of sediment pollution: A case study of Bulgarian and UK rivers by Michailova, P., Ilkova, J., Dean, A.P., White, K.N.

“…The genotoxicity of trace metals in the sediments from a number of polluted sites on UK and Bulgarian rivers to Chironomus piger was assessed by an examination…”
Get full text

Chironomids (Diptera) and their salivary gland chromosomes as indicators of trace-metal genotoxicity by Michailova, P, Sella, G, Petrova, N

“…The long-term impact of pollution in freshwater aquatic environments can be assessed realistically only if the mutagenic effects of pollutants on organisms…”
Get full text

Numerical analysis of Ca2+ signaling in rat ventricular myocytes with realistic transverse-axial tubular geometry and inhibited sarcoplasmic reticulum by Cheng, Yuhui, Yu, Zeyun, Hoshijima, Masahiko, Holst, Michael J, McCulloch, Andrew D, McCammon, J Andrew, Michailova, Anushka P

“…The t-tubules of mammalian ventricular myocytes are invaginations of the cell membrane that occur at each Z-line. These invaginations branch within the cell to…”
Get full text

Effect of Contaminants on the Genome of Some Species of Genus Chironomus (Chironomidae, Diptera) Live in Sediments of Dunajec River and Czorsztyn Reservoir by Michailova, P., Szarek-Gwiazda, E., Kownacki, A.

“…The effect of contaminants on the genomes of Chironomus plumosus L. and Chironomus bernensis Wülker, Klötzli species was studied in the Dunajec River (station…”
Get full text

Modeling beta-adrenergic control of cardiac myocyte contractility in silico by Saucerman, Jeffrey J., Brunton, Laurence L., Michailova, Anushka P., McCulloch, Andrew D., McCullough, A. D.

“…The beta-adrenergic signaling pathway regulates cardiac myocyte contractility through a combination of feedforward and feedback mechanisms. We used systems…”
Get full text

Heavy metal accumulation, heat shock protein expression and cytogenetic changes in Tetrix tenuicornis (L.) (Tetrigidae, Orthoptera) from polluted areas by Warchałowska-Śliwa, E., Niklińska, M., Görlich, A., Michailova, P., Pyza, E.

“…The orthopteran insect Tetrix tenuicornis, collected from polluted and unpolluted areas, was used to study heavy metal accumulation and its impact on stress…”
Get full text

Genotoxic effect of copper on salivary gland polytene chromosomes of Chironomus riparius Meigen 1804 (Diptera, Chironomidae) by Michailova, P., Petrova, N., Ilkova, J., Bovero, S., Brunetti, S., White, K., Sella, G.

“…The genotoxic action of copper (Cu) on the polytene chromosomes of Chironomus riparius was investigated by analysing structural and functional chromosome…”
Get full text

Chromosome variability in Chironomus acidophilus Keyl, 1960 from the Afon Goch, UK - a river subject to long-term trace metal pollution by Michailova, P., Ilkova, J., Kerr, R., White, K.

“…The structure and function of the salivary gland polytene chromosomes of the larvae of the chironomid Chironomus acidophilus in a UK river subject to long-term…”
Get full text

POLYTENE CHROMOSOMES OF DIFFERENT SUBFAMILIES OF FAMILY CHIRONOMIDAE, DIPTERA by P. Michailova

Get full text

Functional and structural rearrangements of salivary gland polytene chromosomes of Chironomus riparius Mg. (Diptera,Chironomidae) in response to freshly neutralized aluminium by Michailova, P, Ilkova, J, White, K.N

“…Aluminium impacts on aquatic biota can be detected using polytene chromosomes as bio-markers Although recent work has shown that environmentally relevant…”
Get full text

Modelling cardiac calcium sparks in a three‐dimensional reconstruction of a calcium release unit by Hake, Johan, Edwards, Andrew G., Yu, Zeyun, Kekenes‐Huskey, Peter M., Michailova, Anushka P., McCammon, J. Andrew, Holst, Michael J., Hoshijima, Masahiko, McCulloch, Andrew D.

“…Key points •  We have developed a detailed computational model of a cardiac Ca2+ spark based on a three dimensional reconstruction of electron tomograms. • …”
Get full text

Modeling Calcium Sparks in a Three-Dimensional Reconstruction of a Cardiac Calcium Release Unit by Hake, Johan E., Edwards, Andrew G., Yu, Zeyun, Kekenes-Huskey, Peter, Michailova, Anushka P., McCammon, Andrew J., Holst, Michael J., Hoshijima, Masahiko, McCulloch, Andrew D.

Get full text

A new species of Chironomus Meigen, 1803 (Diptera, Chironomidae) from the southeast of Brazil by Correia, LCS, Trivinho-Strixino, S, Michailova, P

“…The article describes the larva, pupa, adults and karyotype of Chironomus reissi, sp. n., which live on leaf detritus beds of small temporary waters in the…”
Get full text

Structural–functional rearrangements in chromosome G in Chironomus riparius (Diptera, Chironomidae) collected from a heavy metal-polluted area near Turin, Italy by Michailova, P, Petrova, N, Sella, G, Ramella, L, Bovero, S

“…A natural population of Chironomus riparius from the heavy metal-polluted Piedmont station (Italy) was analysed. Chromosome G, on which the Balbiani rings BRa,…”
Get full text

Implications of Genome Alterations in Chironomus bernensis Klȍtzli (Diptera) for Assessment of Trace Metal Pollution in Two Bulgarian Rivers by Michailova, P., Ilkova, J., White, K.

“…This study assesses the effect of sediment contaminants as indicated by the measurement of trace metal levels in two large Bulgarian rivers (river Maritsa and…”
Get full text

Morphology of the thymus and the specific features of its cellular composition in experimental acute and chronic ulcerative colitis by Postovalova, E A, Makarova, O V, Kosyreva, A M, Michailova, L P

“…To investigate morphological changes in the thymus, the subpopulation composition of lymphocytes and its non-lymphoid cells in dextran-induced experimental…”
Get more information

Comparative Cytogenetic Variation of the Salivary Gland Polytene Chromosomes in Chironomus riparius Mg., 1804 (Diptera, Chironomidae) from Two Polluted Biotopes of Bulgaria and Russia by Petrova, N. A., Michailova, P., Ilkova, J.

Get full text

Implications of Genome Alterations in Chironomus bernensis Kltzli (Diptera) for Assessment of Trace Metal Pollution in Two Bulgarian Rivers by Michailova, P, Ilkova, J, White, K

“…This study assesses the effect of sediment contaminants as indicated by the measurement of trace metal levels in two large Bulgarian rivers (river Maritsa and…”
Get full text