Search Results - "P. Lorenzo"

Nutrient limitation suppresses the temperature dependence of phytoplankton metabolic rates by Marañón, Emilio, Lorenzo, María P., Cermeño, Pedro, Mouriño-Carballido, Beatriz

“…Climate warming has the potential to alter ecosystem function through temperature-dependent changes in individual metabolic rates. The temperature sensitivity…”
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Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity by Victor, Matheus B., Leary, Noelle, Luna, Xochitl, Meharena, Hiruy S., Scannail, Aine Ni, Bozzelli, P. Lorenzo, Samaan, George, Murdock, Mitchell H., von Maydell, Djuna, Effenberger, Audrey H., Cerit, Oyku, Wen, Hsin-Lan, Liu, Liwang, Welch, Gwyneth, Bonner, Maeve, Tsai, Li-Huei

“…Apolipoprotein E4 (APOE4) is the greatest known genetic risk factor for developing sporadic Alzheimer’s disease. How the interaction of APOE4 microglia with…”
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Proteolytic Remodeling of Perineuronal Nets: Effects on Synaptic Plasticity and Neuronal Population Dynamics by Villapol, Sonia, Kim, Eunyoung, Alaiyed, Seham, Lorenzo Bozzelli, P., Conant, Katherine

“…The perineuronal net (PNN) represents a lattice-like structure that is prominently expressed along the soma and proximal dendrites of parvalbumin- (PV-)…”
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Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and -22 Production and Promotes Intestinal Barrier Integrity by Martínez-López, María, Iborra, Salvador, Conde-Garrosa, Ruth, Mastrangelo, Annalaura, Danne, Camille, Mann, Elizabeth R., Reid, Delyth M., Gaboriau-Routhiau, Valérie, Chaparro, Maria, Lorenzo, María P., Minnerup, Lara, Saz-Leal, Paula, Slack, Emma, Kemp, Benjamin, Gisbert, Javier P., Dzionek, Andrzej, Robinson, Matthew J., Rupérez, Francisco J., Cerf-Bensussan, Nadine, Brown, Gordon D., Bernardo, David, LeibundGut-Landmann, Salomé, Sancho, David

“…Production of interleukin-17 (IL-17) and IL-22 by T helper 17 (Th17) cells and group 3 innate lymphoid cells (ILC3s) in response to the gut microbiota ensures…”
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An electronic nose using a single graphene FET and machine learning for water, methanol, and ethanol by Hayasaka, Takeshi, Lin, Albert, Copa, Vernalyn C., Lopez, Lorenzo P., Loberternos, Regine A., Ballesteros, Laureen Ida M., Kubota, Yoshihiro, Liu, Yumeng, Salvador, Arnel A., Lin, Liwei

“…The poor gas selectivity problem has been a long-standing issue for miniaturized chemical-resistor gas sensors. The electronic nose (e-nose) was proposed in…”
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Phytanic acid consumption and human health, risks, benefits and future trends: A review by Roca-Saavedra, P., Mariño-Lorenzo, P., Miranda, J.M., Porto-Arias, J.J., Lamas, A., Vazquez, B.I., Franco, C.M., Cepeda, A.

“…•Phytanic acid is a methyl-branched fatty acid derived from phytol.•Phytanic acid is carried into the human body by means of red meat, dairy products and fatty…”
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Treating insomnia with 40 Hz light flicker by Bozzelli, P. Lorenzo, Tsai, Li-Huei

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Venlafaxine stimulates PNN proteolysis and MMP‐9‐dependent enhancement of gamma power; relevance to antidepressant efficacy by Alaiyed, Seham, Bozzelli, P. Lorenzo, Caccavano, Adam, Wu, Jian Young, Conant, Katherine

“…Drugs that target monoaminergic transmission represent a first‐line treatment for major depression. Though a full understanding of the mechanisms that underlie…”
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Inhibitory Parvalbumin Basket Cell Activity is Selectively Reduced during Hippocampal Sharp Wave Ripples in a Mouse Model of Familial Alzheimer's Disease by Caccavano, Adam, Bozzelli, P Lorenzo, Forcelli, Patrick A, Pak, Daniel T S, Wu, Jian-Young, Conant, Katherine, Vicini, Stefano

“…Memory disruption in mild cognitive impairment (MCI) and Alzheimer's disease (AD) is poorly understood, particularly at early stages preceding…”
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HIV‐1 Tat promotes astrocytic release of CCL2 through MMP/PAR‐1 signaling by Bozzelli, P. Lorenzo, Yin, Tao, Avdoshina, Valeria, Mocchetti, Italo, Conant, Katherine E., Maguire‐Zeiss, Kathleen A.

“…The HIV‐1 protein Tat is continually released by HIV‐infected cells despite effective combination antiretroviral therapies (cART). Tat promotes neurotoxicity…”
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Long‐term automated visual monitoring of Antarctic benthic fauna by Marini, Simone, Bonofiglio, Federico, Corgnati, Lorenzo P., Bordone, Andrea, Schiaparelli, Stefano, Peirano, Andrea

“…The rapid changes in the climate of Antarctica are likely to pose challenges to living communities, which makes monitoring of Antarctic fauna an urgent…”
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Specific Deletion of the Astrocyte Leptin Receptor Induces Changes in Hippocampus Glutamate Metabolism, Synaptic Transmission and Plasticity by Naranjo, Víctor, Contreras, Ana, Merino, Beatriz, Plaza, Adrián, Lorenzo, María P., García-Cáceres, Cristina, García, Antonia, Chowen, Julie A., Ruiz-Gayo, Mariano, Del Olmo, Nuria, Cano, Victoria

“…•Astrocyte LepR deletion reduces basal synaptic transmission in the hippocampus.•Astrocyte LepR modulate NMDA-induced LTD within the hippocampus.•Astrocyte…”
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Increased matrix metalloproteinase levels and perineuronal net proteolysis in the HIV-infected brain; relevance to altered neuronal population dynamics by Bozzelli, P. Lorenzo, Caccavano, Adam, Avdoshina, Valeria, Mocchetti, Italo, Wu, Jian-Young, Conant, Katherine

“…HIV-associated neurocognitive disorders (HAND) continue to persist despite effective control of viral replication. Although the mechanisms underlying HAND are…”
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MEF2 is a key regulator of cognitive potential and confers resilience to neurodegeneration by Barker, Scarlett J, Raju, Ravikiran M, Milman, Noah E P, Wang, Jun, Davila-Velderrain, Jose, Gunter-Rahman, Fatima, Parro, Cameron C, Bozzelli, P Lorenzo, Abdurrob, Fatema, Abdelaal, Karim, Bennett, David A, Kellis, Manolis, Tsai, Li-Huei

“…Recent increases in human longevity have been accompanied by a rise in the incidence of dementia, highlighting the need to preserve cognitive function in an…”
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Multisensory gamma stimulation mitigates the effects of demyelination induced by cuprizone in male mice by Rodrigues-Amorim, Daniela, Bozzelli, P. Lorenzo, Kim, TaeHyun, Liu, Liwang, Gibson, Oliver, Yang, Cheng-Yi, Murdock, Mitchell H., Galiana-Melendez, Fabiola, Schatz, Brooke, Davison, Alexis, Islam, Md Rezaul, Shin Park, Dong, Raju, Ravikiran M., Abdurrob, Fatema, Nelson, Alissa J., Min Ren, Jian, Yang, Vicky, Stokes, Matthew P., Tsai, Li-Huei

“…Demyelination is a common pathological feature in a wide range of diseases, characterized by the loss of myelin sheath and myelin-supporting oligodendrocytes…”
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A Path Toward Sustainable Development Along the Belt and Road by Lorenzo, Johanna Aleria P

“…ABSTRACT The article scrutinizes the purported synergies between the Belt and Road Initiative (BRI) and the United Nations (UN) 2030 Agenda for Sustainable…”
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High-fat diets induce changes in hippocampal glutamate metabolism and neurotransmission by Valladolid-Acebes, Ismael, Merino, Beatriz, Principato, Antonio, Fole, Alberto, Barbas, Coral, Lorenzo, María P, García, Antonia, Del Olmo, Nuria, Ruiz-Gayo, Mariano, Cano, Victoria

“…Obesity and high-fat (HF) diets have a deleterious impact on hippocampal function and lead to impaired synaptic plasticity and learning deficits. Because all…”
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A Rapid Environmental Scan of South Florida HIV Organizations’ Mpox Messaging During the August 2022 Peak of the U.S. Outbreak by Atuluru, Pranusha, Weinstein, Elliott R., Serrano, Lorenzo P., Doblecki-Lewis, Susanne, Rogers, Brooke G., Harkness, Audrey

“…The 2022 outbreak of mpox disproportionately impacted men who have sex with men and people living with HIV. As such, HIV organizations were uniquely situated…”
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Alterations in a cross-hemispheric circuit associates with novelty discrimination deficits in mouse models of neurodegeneration by Adaikkan, Chinnakkaruppan, Wang, Jun, Abdelaal, Karim, Middleton, Steven J., Bozzelli, P. Lorenzo, Wickersham, Ian R., McHugh, Thomas J., Tsai, Li-Huei

“…A major pathological hallmark of neurodegenerative diseases, including Alzheimer’s, is a significant reduction in the white matter connecting the two cerebral…”
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Matrix metalloproteinase activity stimulates N-cadherin shedding and the soluble N-cadherin ectodomain promotes classical microglial activation by Conant, Katherine, Daniele, Stefano, Bozzelli, P Lorenzo, Abdi, Tsion, Edwards, Amanda, Szklarczyk, Arek, Olchefske, India, Ottenheimer, David, Maguire-Zeiss, Kathleen

“…Matrix metalloproteinases (MMPs) are a family of enzymes that are typically released from intracellular stores to act on specific extracellular substrates. MMP…”
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