Search Results - "P Thomas, Olivier"
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Marine Anticancer Agents: An Overview with a Particular Focus on Their Chemical Classes
Published in Marine drugs (04-12-2020)“…The marine environment is a rich source of biologically active molecules for the treatment of human diseases, especially cancer. The adaptation to unique…”
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Bis-Indole Alkaloids Isolated from the Sponge Spongosorites calcicola Disrupt Cell Membranes of MRSA
Published in International journal of molecular sciences (11-02-2022)“…Antimicrobial resistance (AMR) is a global health challenge with methicillin resistant (MRSA), a leading cause of nosocomial infection. In the search for novel…”
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Rapid Biotic and Abiotic Transformation of Toxins produced by Ostreopsis. cf. ovata
Published in Marine drugs (28-11-2022)“…The dinoflagellate Ostreopsis cf. ovata produces several families of toxic polyketides. Despite only a few field measurements of these phycotoxins in seawater…”
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Poriferans rift apart: molecular demosponge biodiversity in Central and French Polynesia and comparison with adjacent marine provinces of the Central Indo-Pacific
Published in Biodiversity and conservation (01-06-2023)“…The distribution of marine sponges in the tropical Southwest Pacific Ocean is largely unexplored despite the vital ecological role of sponges in coral reefs…”
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Antibacterial Activity and Amphidinol Profiling of the Marine Dinoflagellate Amphidinium carterae (Subclade III)
Published in International journal of molecular sciences (11-11-2021)“…Microalgae have received growing interest for their capacity to produce bioactive metabolites. This study aimed at characterising the antimicrobial potential…”
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Optimization of LC-MS2 Data Acquisition Parameters for Molecular Networking Applied to Marine Natural Products
Published in Metabolites (14-03-2022)“…Since the introduction of the online open-source GNPS, molecular networking has quickly become a widely applied tool in the field of natural products…”
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Terrazoanthines, 2‑Aminoimidazole Alkaloids from the Tropical Eastern Pacific Zoantharian Terrazoanthus onoi
Published in Organic letters (07-04-2017)“…The first chemical study of the common species Terrazoanthus onoi, present off the coast of Ecuador, led to the identification of a new family of…”
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Structure Elucidation and Biological Evaluation of Maitotoxin-3, a Homologue of Gambierone, from Gambierdiscus belizeanus
Published in Toxins (01-02-2019)“…species are the producers of the marine toxins ciguatoxins and maitotoxins which cause worldwide human intoxications recognized as Ciguatera Fish Poisoning. A…”
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Antioxidant and Cytoprotective Activities of Fucus spiralis Seaweed on a Human Cell in Vitro Model
Published in International journal of molecular sciences (01-02-2017)“…Antioxidants play an important role as Reactive Oxygen Species (ROS) chelating agents and, therefore, the screening for potent antioxidants from natural…”
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On the use of 31P NMR for the quantification of hydrosoluble phosphorus-containing compounds in coral host tissues and cultured zooxanthellae
Published in Scientific reports (23-02-2016)“…31 P Nuclear Magnetic Resonance (NMR) was assessed to investigate the phosphorus-containing compounds present in the tissues of the scleractinian coral…”
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Brominated Bisindole Alkaloids from the Celtic Sea Sponge Spongosorites calcicola
Published in Molecules (Basel, Switzerland) (29-10-2019)“…As part of an ongoing program to identify new bioactive compounds from Irish marine bioresources, we selected the subtidal sponge for chemical study, as…”
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Antitumor and antimicrobial potential of bromoditerpenes isolated from the red alga, Sphaerococcus coronopifolius
Published in Marine drugs (26-01-2015)“…Cancer and infectious diseases continue to be a major public health problem, and new drugs are necessary. As marine organisms are well known to provide a wide…”
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Cytotoxic and Anti-Inflammatory Effects of Ent -Kaurane Derivatives Isolated from the Alpine Plant Sideritis hyssopifolia
Published in Molecules (Basel, Switzerland) (29-01-2020)“…This paper reports the isolation and structural characterization of four new -kaurane derivatives from the Lamiaceae plant . Planar structures and relative…”
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Unveiling the Chemical Diversity of the Deep-Sea Sponge Characella pachastrelloides
Published in Marine drugs (05-01-2022)“…Sponges are at the forefront of marine natural product research. In the deep sea, extreme conditions have driven secondary metabolite pathway evolution such…”
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Assessing the Zoantharian Diversity of the Tropical Eastern Pacific through an Integrative Approach
Published in Scientific reports (08-05-2018)“…Zoantharians represent a group of marine invertebrates widely distributed from shallow waters to the deep sea. Despite a high diversity and abundance in the…”
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How a collaborative integrated taxonomic effort has trained new spongiologists and improved knowledge of Martinique Island (French Antilles, eastern Caribbean Sea) marine biodiversity
Published in PloS one (22-03-2017)“…Although sponges are important components of benthic ecosystems of the Caribbean Sea, their diversity remained poorly investigated in the Lesser Antilles. By…”
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A Novel High-Throughput Screening Platform Identifies Itaconate Derivatives from Marine Penicillium antarcticum as Inhibitors of Mesenchymal Stem Cell Differentiation
Published in Marine drugs (05-04-2020)“…Worldwide diffused diseases such as osteoarthritis, atherosclerosis or chronic kidney disease are associated with a tissue calcification process which may…”
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Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra
Published in Marine drugs (30-05-2019)“…So far, the Futuna Islands located in the Central Indo-Pacific Ocean have not been inventoried for their diversity in marine sponges and associated chemical…”
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Zoanthamine Alkaloids from the Zoantharian Zoanthus cf. pulchellus and Their Effects in Neuroinflammation
Published in Marine drugs (20-07-2018)“…Two new zoanthamine alkaloids, namely 3-acetoxynorzoanthamine ( ) and 3-acetoxyzoanthamine ( ), have been isolated from the zoantharian cf. collected off the…”
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Additional Cytotoxic Pyridoacridine Alkaloids from the Ascidian Cystodytes violatinctus and Biogenetic Considerations
Published in Journal of natural products (Washington, D.C.) (27-09-2013)“…The extraction and purification of the bioactive extract of Cystodytes violatinctus (Solomon Islands) led to the isolation and identification of six…”
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