Search Results - "P S Yeong, Joe"
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Predictive Biomarkers of Immune Checkpoint Inhibition in Gastroesophageal Cancers
Published in Frontiers in oncology (15-05-2020)“…Immune checkpoint inhibition has transformed cancer treatment. For gastroesophageal cancer, this class of drugs have demonstrated durable responses and…”
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Quantitative imaging of RAD51 expression as a marker of platinum resistance in ovarian cancer
Published in EMBO molecular medicine (07-05-2021)“…Early relapse after platinum chemotherapy in epithelial ovarian cancer (EOC) portends poor survival. A‐priori identification of platinum resistance is…”
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Higher densities of tumour‐infiltrating lymphocytes and CD4+ T cells predict recurrence and progression of ductal carcinoma in situ of the breast
Published in Histopathology (01-05-2020)“…Aims Host immunity influences cancer progression and therapeutic response. We investigated the potential of tumour‐infiltrating lymphocytes (TILs) around…”
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Delineating the breast cancer immune microenvironment in the era of multiplex immunohistochemistry/immunofluorescence
Published in Histopathology (01-08-2021)“…Breast cancer is the most common malignancy and the leading cause of cancer death in females worldwide. Treatment is challenging, especially for those who are…”
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Integrative Profiling of T790M-Negative EGFR-Mutated NSCLC Reveals Pervasive Lineage Transition and Therapeutic Opportunities
Published in Clinical cancer research (01-11-2021)“…Despite the established role of EGFR tyrosine kinase inhibitors (TKIs) in -mutated NSCLC, drug resistance inevitably ensues, with a paucity of treatment…”
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Clinical and Genomic Features of HER2 Exon 20 Insertion Mutations and Characterization of HER2 Expression by Immunohistochemistry in East Asian Non-Small-Cell Lung Cancer
Published in JCO precision oncology (01-10-2022)“…-altered non-small-cell lung cancer (NSCLC) represents a diverse subgroup, including mutations, amplifications, and overexpression. However, exon 20 insertion…”
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Transcriptomic analyses of localized prostate cancers of East Asian and North American men reveal race‐specific luminal‐basal and microenvironmental differences
Published in Cancer communications (London, England) (01-10-2023)“…Abbreviations AR Androgen receptor CPGEA Chinese Prostate Cancer Genome and Epigenome Atlas CHD1 Chromodomain-Helicase DNA-binding 1 DMFS Distant…”
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A Randomized Phase 2 Trial of Nivolumab Versus Nivolumab-Ipilimumab Combination in EGFR-Mutant NSCLC
Published in JTO clinical and research reports (01-12-2022)“…Although immune checkpoint inhibitors (ICIs) have dramatically improved outcomes for nononcogene-addicted NSCLC, monotherapy with programmed cell death…”
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