Search Results - "Püschel, Klaus"
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1
Microplastics detected in cirrhotic liver tissue
Published in EBioMedicine (01-08-2022)“…The contamination of ecosystem compartments by microplastics (MPs) is an ubiquitous problem. MPs have been observed in mice tissues, and recently in human…”
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2
Deep spatial profiling of human COVID-19 brains reveals neuroinflammation with distinct microanatomical microglia-T-cell interactions
Published in Immunity (Cambridge, Mass.) (13-07-2021)“…COVID-19 can cause severe neurological symptoms, but the underlying pathophysiological mechanisms are unclear. Here, we interrogated the brain stems and…”
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3
Investigating the use of PEth, CDT and MCV to evaluate alcohol consumption in a cohort of homeless individuals– A comparison of different alcohol biomarkers
Published in Forensic science international (01-02-2022)“…In a cohort including individuals with suspected high alcohol consumption, the concentrations of the indirect alcohol biomarkers…”
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4
Presence of SARS-CoV-2 RNA in the Cornea of Viremic Patients With COVID-19
Published in JAMA ophthalmology (01-04-2021)“…Current recommendations are to avoid tissue for corneal transplant from donors with coronavirus disease 2019 (COVID-19) or those who were recently exposed to…”
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5
Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa
Published in Emerging infectious diseases (01-01-2021)“…Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem…”
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6
Osteocytic Canalicular Networks: Morphological Implications for Altered Mechanosensitivity
Published in ACS nano (24-09-2013)“…Osteocytes are ramified bone cells distributed throughout the bone matrix within a network of micrometer-scale cavities (lacunae) and numerous nanometer-thick…”
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7
Insufficient stability of pedicle screws in osteoporotic vertebrae: biomechanical correlation of bone mineral density and pedicle screw fixation strength
Published in European spine journal (01-11-2017)“…Purpose Loosening of pedicle screws is one major complication of posterior spinal stabilisation, especially in the patients with osteoporosis. Augmentation of…”
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8
Bone microarchitecture of the tibial plateau in skeletal health and osteoporosis
Published in The knee (01-08-2018)“…Impaired bone structure poses a challenge for the treatment of osteoporotic tibial plateau fractures. As knowledge of region-specific structural bone…”
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9
Death after percutaneous dilatational tracheostomy: a systematic review and analysis of risk factors
Published in Critical care (London, England) (29-10-2013)“…Since the introduction and widespread acceptance of percutaneous techniques in the intensive care unit (ICU) setting, the number of critically ill patients…”
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10
Conventional rotator cuff versus all-suture anchors-A biomechanical study focusing on the insertion angle in an unlimited cyclic model
Published in PloS one (27-11-2019)“…The purpose of this study was to compare the biomechanical properties of an all-suture anchor to a conventional anchor used commonly in rotator cuff repairs…”
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11
Calcification of the acetabular labrum of the hip: prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration
Published in Arthritis research & therapy (30-05-2018)“…Meniscal calcification is considered to play a relevant role in the pathogenesis of osteoarthritis of the knee. Little is known about the biology of acetabular…”
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12
Decrease in the osteocyte lacunar density accompanied by hypermineralized lacunar occlusion reveals failure and delay of remodeling in aged human bone
Published in Aging cell (01-12-2010)“…Summary Aging decreases the human femur’s fatigue resistance, impact energy absorption, and the ability to withstand load. Changes in the osteocyte…”
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13
Bone mineralization defects and vitamin D deficiency: Histomorphometric analysis of iliac crest bone biopsies and circulating 25‐hydroxyvitamin D in 675 patients
Published in Journal of bone and mineral research (01-02-2010)“…Parathyroid hormone (PTH) is only one measurable index of skeletal health, and we reasoned that a histomorphometric analysis of iliac crest biopsies would be…”
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14
Mechanical Competence and Bone Quality Develop During Skeletal Growth
Published in Journal of bone and mineral research (01-08-2019)“…ABSTRACT Bone fracture risk is influenced by bone quality, which encompasses bone's composition as well as its multiscale organization and architecture. Aging…”
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Bone tissue aging affects mineralization of cement lines
Published in Bone (New York, N.Y.) (01-05-2018)“…Cement lines are known as thin peripheral boundaries of the osteons. With a thickness below 5 μm their composition of inorganic and organic compounds has been…”
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Intrinsic mechanical behavior of femoral cortical bone in young, osteoporotic and bisphosphonate-treated individuals in low- and high energy fracture conditions
Published in Scientific reports (16-02-2016)“…Bisphosphonates are a common treatment to reduce osteoporotic fractures. This treatment induces osseous structural and compositional changes accompanied by…”
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17
Early bone tissue aging in human auditory ossicles is accompanied by excessive hypermineralization, osteocyte death and micropetrosis
Published in Scientific reports (30-01-2018)“…Within the mineralized bone, osteocytes form a multifunctional mechanosensitive network orchestrating bone remodelling. A preserved osteocyte population is a…”
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Fatal outcomes of endoscopy: an analysis from the coronerʼs point of view
Published in Endoscopy International Open (01-04-2023)“…Abstract Background and study aims This study was designed to provide a profound analysis of fatalities associated with endoscopic procedures. Methods …”
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Defective NET clearance contributes to sustained FXII activation in COVID-19-associated pulmonary thrombo-inflammation
Published in EBioMedicine (01-05-2021)“…Coagulopathy and inflammation are hallmarks of Coronavirus disease 2019 (COVID-19) and are associated with increased mortality. Clinical and experimental data…”
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20
The handling of SARS-CoV-2 associated deaths - infectivity of the body
Published in Forensic science, medicine, and pathology (01-09-2021)“…The body of a deceased with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection is considered infectious. In this study, we present the…”
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