Search Results - "Pérusse, L."

Genome-wide association studies suggest sex-specific loci associated with abdominal and visceral fat by Sung, Y J, Pérusse, L, Sarzynski, M A, Fornage, M, Sidney, S, Sternfeld, B, Rice, T, Terry, J G, Jacobs, D R, Katzmarzyk, P, Curran, J E, Jeffrey Carr, J, Blangero, J, Ghosh, S, Després, J-P, Rankinen, T, Rao, D C, Bouchard, C

“…Background: To identify loci associated with abdominal fat and replicate prior findings, we performed genome-wide association (GWA) studies of abdominal fat…”
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The prediction of abdominal visceral fat level from body composition and anthropometry : ROC analysis by RANKINEN, T, KIM, S.-Y, PERUSSE, L, DESPRES, J.-P, BOUCHARD, C

“…To evaluate the merit of body mass index (BMI), % body fat, waist circumference and waist-to-hip ratio as predictors of abdominal visceral fat (AVF) level…”
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Melanocortin-4 receptor gene and physical activity in the Québec Family Study by LOOS, R. J. F, RANKINEN, T, TREMBLAY, A, PERUSSE, L, CHAGNON, Y, BOUCHARD, C

“…Physical inactivity is a risk factor for numerous chronic diseases. Low compliance with interventions to increase activity suggests involvement of biological…”
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The PPAR-gamma P12A polymorphism modulates the relationship between dietary fat intake and components of the metabolic syndrome: results from the Québec Family Study by Robitaille, J, Després, J-P, Pérusse, L, Vohl, M-C

“…The metabolic syndrome is a complex disorder characterized by an atherogenic dyslipidemia resulting from the interaction between genetic and nutritional…”
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Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family Study by SEIDELL, Jacob C, PERUSSE, Louis, DESPRES, Jean-Pierre, BOUCHARD, Claude

“…A high waist-to-hip ratio is associated with unfavorable cardiovascular disease risk factors. This could be due to either a relatively large waist or a small…”
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Genome-wide linkage scan reveals multiple susceptibility loci influencing lipid and lipoprotein levels in the Québec Family Study by Bossé, Y., Chagnon, Y.C., Després, J-P., Rice, T., Rao, D.C., Bouchard, C., Pérusse, L., Vohl, M-C.

“…A genome-wide linkage study was performed to identify chromosomal regions harboring genes influencing lipid and lipoprotein levels. Linkage analyses were…”
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Polymorphisms in the leptin and leptin receptor genes in relation to resting metabolic rate and respiratory quotient in the Québec Family Study by LOOS, R. J. F, RANKINEN, T, CHAGNON, Y, TREMBLAY, A, PERUSSE, L, BOUCHARD, C

“…Leptin (LEP) is an endocrine hormone that participates in many metabolic pathways, including those associated with the central regulation of energy…”
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Stability of indicators of the metabolic syndrome from childhood and adolescence to young adulthood: the Québec Family Study by Katzmarzyk, Peter T, Pérusse, Louis, Malina, Robert M, Bergeron, Jean, Després, Jean-Pierre, Bouchard, Claude

“…The stability of indicators of the metabolic syndrome from childhood and adolescence to young adulthood was examined. The sample included 76 males and 71…”
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Familial resemblance for VO2max in the sedentary state: the HERITAGE family study by Bouchard, C, Daw, E W, Rice, T, Pérusse, L, Gagnon, J, Province, M A, Leon, A S, Rao, D C, Skinner, J S, Wilmore, J H

“…This study investigates the familial resemblance of maximal oxygen uptake (VO2max) based on data from 86 nuclear families of Caucasian descent participating in…”
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A Glucocorticoid Receptor Gene Marker Is Associated with Abdominal Obesity, Leptin, and Dysregulation of the Hypothalamic-Pituitary-Adrenal Axis by Rosmond, Roland, Chagnon, Yvon C., Holm, Göran, Chagnon, Monique, Pérusse, Louis, Lindell, Kajsa, Carlsson, Björn, Bouchard, Claude, Björntorp, Per

“…Objective: Abdominal obesity has a key role in the pathogenesis of prevalent and serious diseases and has been shown to be associated with an altered…”
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Genome-wide linkage analysis of systolic and diastolic blood pressure : The Québec Family Study by RICE, Treva, RANKINEN, Tuomo, PROVINCE, Michael A, CHAGNON, Yvon C, PERUSSE, Louis, BORECKI, Ingrid B, BOUCHARD, Claude, RAO, D. C

“…Blood pressure (BP), an important risk factor for coronary heart disease, is a complex trait with multiple genetic etiologies. While some loci affecting BP…”
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Interactions among the glucocorticoid receptor, lipoprotein lipase and adrenergic receptor genes and abdominal fat in the Québec Family Study by UKKOLA, O, PERUSSE, L, CHAGNON, Y. C, DESPRES, J.-P, BOUCHARD, C

“…To investigate whether interactions between glucocorticoid receptor (GRL), lipoprotein lipase (LPL) and adrenergic receptor (ADR) gene markers contribute to…”
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Linkages and associations between the leptin receptor (LEPR) gene and human body composition in the Québec Family Study by CHAGNON, Y. C, CHUNG, W. K, PERUSSE, L, CHAGNON, M, LEIBEL, R. L, BOUCHARD, C

“…To investigate linkage and association between the leptin receptor (LEPR) gene and body composition variables in the Quebec Family Study (QFS). Single-point…”
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Hypertension in obesity and the leptin receptor gene locus by Rosmond, R, Chagnon, Y C, Holm, G, Chagnon, M, Pérusse, L, Lindell, K, Carlsson, B, Bouchard, C, Björntorp, P

“…Recent animal studies indicate that leptin is involved in the regulation of blood pressure through the leptin receptor. Therefore, 51-yr-old men (N = 284) were…”
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Genotype-Environment Interaction in Human Obesity by Pérusse, Louis, Bouchard, Claude

“…The data reviewed in this paper reveal that individual differences in the response to alterations in energy balance induced by diet or exercise are ubiquitous…”
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Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q by Lembertas, A V, Pérusse, L, Chagnon, Y C, Fisler, J S, Warden, C H, Purcell-Huynh, D A, Dionne, F T, Gagnon, J, Nadeau, A, Lusis, A J, Bouchard, C

“…Chromosomal synteny between the mouse model and humans was used to map a gene for the complex trait of obesity. Analysis of NZB/BINJ x SM/J intercross mice…”
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Plasma concentrations of apolipoprotein B are modulated by a gene–diet interaction effect between the LFABP T94A polymorphism and dietary fat intake in French-Canadian men by Robitaille, J., Brouillette, C., Lemieux, S., Pérusse, L., Gaudet, D., Vohl, M.C.

“…Hyperapobetalipoproteinemia is a common feature of the metabolic syndrome and could result from the interaction between genetic and dietary factors. The…”
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Associations between dietary patterns and obesity phenotypes by Paradis, A.M, Godin, G, Perusse, L, Vohl, M.C

“…Objective: To examine whether dietary patterns are associated with obesity phenotypes. Design: Cross-sectional study. Subjects: We recruited 664 participants…”
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Human resistin gene polymorphism is associated with visceral obesity and fasting and oral glucose stimulated C-peptide in the Québec Family Study by Bouchard, L, Weisnagel, S J, Engert, J C, Hudson, T J, Bouchard, C, Vohl, M C, Pérusse, L

“…Obesity and insulin resistance are common features of Type 2 Diabetes. A new protein called resistin has been shown to be secreted by adipocytes in mice and to…”
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No association between the angiotensin-converting enzyme ID polymorphism and elite endurance athlete status by Rankinen, Tuomo, Wolfarth, Bernd, Simoneau, Jean-Aime, Maier-Lenz, Dirk, Rauramaa, Rainer, Rivera, Miguel A, Boulay, Marcel R, Chagnon, Yvon C, Perusse, Louis, Keul, Joseph, Bouchard, Claude

“…1  Pennington Biomedical Research Center, Human Genomics Laboratory, Baton Rouge, Louisiana 70808-4124; 2  Department of Prevention, Rehabilitation, and Sports…”
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