Search Results - "Pérez‐Blanco, Jonás Samuel"

External evaluation of population pharmacokinetic models of imatinib in adults diagnosed with chronic myeloid leukaemia by Corral Alaejos, Álvaro, Zarzuelo Castañeda, Aránzazu, Jiménez Cabrera, Silvia, Sánchez‐Guijo, Fermín, Otero, María José, Pérez‐Blanco, Jonás Samuel

“…Aims Imatinib is considered the standard first‐line treatment in newly diagnosed patients with chronic‐phase myeloid leukaemia (CML). Several imatinib…”
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Model-Informed Precision Dosing (MIPD) by Pérez-Blanco, Jonás Samuel, Lanao, José M

“…Model-informed precision dosing (MIPD) is an advanced quantitative approach focusing on individualized dosage optimization, integrating complex mathematical…”
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Population Pharmacokinetics of Apalutamide and its Active Metabolite N-Desmethyl-Apalutamide in Healthy and Castration-Resistant Prostate Cancer Subjects by Pérez-Ruixo, Carlos, Pérez-Blanco, Jonás Samuel, Chien, Caly, Yu, Margaret, Ouellet, Daniele, Pérez-Ruixo, Juan-José, Ackaert, Oliver

“…Background Apalutamide is a next-generation androgen receptor inhibitor approved for treatment of subjects with high-risk, non-metastatic, castration-resistant…”
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Physiologically-based pharmacokinetic modelling and dosing evaluation of gentamicin in neonates using PhysPK by Zazo, Hinojal, Lagarejos, Eduardo, Prado-Velasco, Manuel, Sánchez-Herrero, Sergio, Serna, Jenifer, Rueda-Ferreiro, Almudena, Martín-Suárez, Ana, Calvo, M Victoria, Pérez-Blanco, Jonás Samuel, Lanao, José M

“…Each year, infections caused around the 25% of neonatal deaths. Early empirical treatments help to reduce this mortality, although optimized dosing regimens…”
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Population pharmacokinetics of doxorubicin and doxorubicinol in patients diagnosed with non‐Hodgkin's lymphoma by Pérez‐Blanco, Jonás Samuel, Santos‐Buelga, Dolores, Fernández de Gatta, María del Mar, Hernández‐Rivas, Jesús María, Martín, Alejandro, García, María José

“…Aims The aims of the study were: (i) to characterize the pharmacokinetics (PK) of doxorubicin (DOX) and doxorubicinol (DOXol) in patients diagnosed with…”
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Population Pharmacokinetics of Valproic Acid in Pediatric and Adult Caucasian Patients by Teixeira-da-Silva, Paulo, Pérez-Blanco, Jonás Samuel, Santos-Buelga, Dolores, Otero, María José, García, María José

“…(1) Background: The aim of this study was to explore the valproic acid (VPA) pharmacokinetic characteristics in a large population of pediatric and adult…”
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Usalpharma: A Cloud-Based Architecture to Support Quality Assurance Training Processes in Health Area Using Virtual Worlds by Martín-Suárez, Ana, Pérez-Blanco, Jonás Samuel, Maderuelo, Cristina, Cruz-Benito, Juan, García-Peñalvo, Francisco J.

“…This paper discusses how cloud-based architectures can extend and enhance the functionality of the training environments based on virtual worlds and how, from…”
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Biomarkers of disease activity and other factors as predictors of adalimumab pharmacokinetics in inflammatory bowel disease by Sánchez-Hernández, José Germán, Pérez-Blanco, Jonás Samuel, Rebollo, Noemí, Muñoz, Fernando, Prieto, Vanessa, Calvo, María Victoria

“…Inflammatory bowel disease (IBD) is commonly treated with adalimumab. The main objective of the study was to develop a population pharmacokinetic model of…”
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Evaluation of Current Amikacin Dosing Recommendations and Development of an Interactive Nomogram: The Role of Albumin by Pérez-Blanco, Jonás Samuel, Sáez Fernández, Eva María, Calvo, María Victoria, Lanao, José M, Martín-Suárez, Ana

“…This study aimed to evaluate the potential efficacy and safety of the amikacin dosage proposed by the main guidelines and to develop an interactive nomogram,…”
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Parametric and Nonparametric Population Pharmacokinetic Models to Assess Probability of Target Attainment of Imipenem Concentrations in Critically Ill Patients by de Velde, Femke, de Winter, Brenda C M, Neely, Michael N, Strojil, Jan, Yamada, Walter M, Harbarth, Stephan, Huttner, Angela, van Gelder, Teun, Koch, Birgit C P, Muller, Anouk E, On Behalf Of The Combacte-Net Consortium

“…Population pharmacokinetic modeling and simulation (M&S) are used to improve antibiotic dosing. Little is known about the differences in parametric and…”
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Population pharmacokinetics of a posaconazole tablet formulation in transplant adult allogeneic stem cell recipients by Peña-Lorenzo, Diego, Rebollo, Noemí, Sánchez-Hernández, José Germán, Zarzuelo-Castañeda, Aránzazu, Vázquez-López, Lourdes, Otero, María José, Pérez-Blanco, Jonás Samuel

“…•A popPK model of posaconazole tablets in allogeneic SCT adult recipients is presented.•Gender and serum proteins showed a significant impact on posaconazole…”
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Amikacin initial dosage in patients with hypoalbuminaemia: an interactive tool based on a population pharmacokinetic approach by Pérez-Blanco, Jonás Samuel, Sáez Fernández, Eva María, Calvo, M Victoria, Lanao, José M, Martín-Suárez, Ana

“…To characterize amikacin population pharmacokinetics in patients with hypoalbuminaemia and to develop a model-based interactive application for amikacin…”
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Evaluation of renal function equations to predict amikacin clearance by Sáez Fernández, Eva María, Pérez-Blanco, Jonás Samuel, Lanao, José M, Calvo, M Victoria, Martín-Suárez, Ana

“…: To evaluate the predictive performance of eight renal function equations to describe amikacin elimination in a large standard population with a wide range of…”
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Validation and clinical evaluation of a UHPLC method with fluorescence detector for plasma quantification of doxorubicin and doxorubicinol in haematological patients by Pérez-Blanco, Jonás Samuel, Fernández de Gatta, María del Mar, Hernández-Rivas, Jesús María, García Sánchez, María José, Sayalero Marinero, María Luisa, González López, Francisco

“…A rapid and simple UHPLC–fluorescence detection method for the quantification of doxorubicin and its main metabolite, doxorubicinol, in human plasma has been…”
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Usalpharma: A Software Architecture to Support Learning in Virtual Worlds by Cruz-Benito, Juan, Maderuelo, Cristina, Garcia-Penalvo, Francisco Jose, Theron, Roberto, Perez-Blanco, Jonas Samuel, Gomez, Hinojal Zazo, Martin-Suarez, Ana

“…This paper explains how a software architecture was planned, designed, and implemented to help in the support of eLearning activities within a virtual…”
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Monitoring and feedback of learning processes in virtual worlds through analytics architectures: A real case by Cruz-Benito, Juan, Therón, Roberto, García-Peñalvo, Francisco J., Maderuelo, Cristina, Pérez-Blanco, Jonás Samuel, Zazo, Hinojal, Martín-Suárez, Ana

“…The application of techniques related to Learning Analytics, including the recovery and processing of data and evidences related with the learning tasks, might…”
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Using software architectures to retrieve interaction information in eLearning environments by Cruz Benito, Juan, Garcia-Penalvo, Francisco J., Theron, Roberto, Maderuelo, Cristina, Perez-Blanco, Jonas Samuel, Zazo, Hinojal, Martin-Suarez, Ana

“…This research paper presents a software architecture based on services and deployed in a cloud environment that retrieves, analyzes and presents information…”
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