Search Results - "Pérez, Vicente Herranz"
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Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity
Published in Developmental cell (20-12-2021)“…Centrioles comprise the heart of centrosomes, microtubule-organizing centers. To study the function of centrioles in lung and gut development, we genetically…”
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2
Transcriptomic analysis links diverse hypothalamic cell types to fibroblast growth factor 1-induced sustained diabetes remission
Published in Nature communications (07-09-2020)“…In rodent models of type 2 diabetes (T2D), sustained remission of hyperglycemia can be induced by a single intracerebroventricular (icv) injection of…”
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3
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis
Published in eLife (15-02-2023)“…Centrosomes are orbited by centriolar satellites, dynamic multiprotein assemblies nucleated by Pericentriolar material 1 (PCM1). To study the requirement for…”
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4
Identification of the growth cone as a probe and driver of neuronal migration in the injured brain
Published in Nature communications (09-03-2024)“…Axonal growth cones mediate axonal guidance and growth regulation. We show that migrating neurons in mice possess a growth cone at the tip of their leading…”
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ID4 Is Required for Normal Ependymal Cell Development
Published in Frontiers in neuroscience (22-04-2021)“…Ependymal cells are radial glia-derived multiciliated cells lining the lateral ventricles of the brain and spinal cord. Correct development and coordinated…”
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The aged brain: genesis and fate of residual progenitor cells in the subventricular zone
Published in Frontiers in cellular neuroscience (24-09-2015)“…Neural stem cells (NSCs) persist in the adult mammalian brain through life. The subventricular zone (SVZ) is the largest source of stem cells in the nervous…”
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7
Regional distribution of the leucine-rich glioma inactivated ( LGI ) gene family transcripts in the adult mouse brain
Published in Brain research (11-01-2010)“…Abstract The leucine-rich glioma inactivated ( LGI ) gene subfamily contains four highly conserved members ( LGI1 , 2 , 3 and 4 ), which have been described in…”
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8
An Actin Network Dispatches Ciliary GPCRs into Extracellular Vesicles to Modulate Signaling
Published in Cell (12-01-2017)“…Signaling receptors dynamically exit cilia upon activation of signaling pathways such as Hedgehog. Here, we find that when activated G protein-coupled…”
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Immature excitatory neurons develop during adolescence in the human amygdala
Published in Nature communications (21-06-2019)“…The human amygdala grows during childhood, and its abnormal development is linked to mood disorders. The primate amygdala contains a large population of…”
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10
Radial Glial Fibers Promote Neuronal Migration and Functional Recovery after Neonatal Brain Injury
Published in Cell stem cell (04-01-2018)“…Radial glia (RG) are embryonic neural stem cells (NSCs) that produce neuroblasts and provide fibers that act as a scaffold for neuroblast migration during…”
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Dynamic Changes in the Neurogenic Potential in the Ventricular–Subventricular Zone of Common Marmoset during Postnatal Brain Development
Published in Cerebral cortex (New York, N.Y. 1991) (01-06-2020)“…Abstract Even after birth, neuronal production continues in the ventricular–subventricular zone (V–SVZ) and hippocampus in many mammals. The immature new…”
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Loss of Dishevelleds Disrupts Planar Polarity in Ependymal Motile Cilia and Results in Hydrocephalus
Published in Neuron (Cambridge, Mass.) (06-08-2014)“…Defects in ependymal (E) cells, which line the ventricle and generate cerebrospinal fluid flow through ciliary beating, can cause hydrocephalus. Dishevelled…”
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Ependymoma associated protein Zfta is expressed in immature ependymal cells but is not essential for ependymal development in mice
Published in Scientific reports (27-01-2022)“…The fusion protein of uncharacterised zinc finger translocation associated (ZFTA) and effector transcription factor of tumorigenic NF-κB signalling, RELA…”
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14
Editorial: New Insights Into Adult Neurogenesis and Neurodegeneration: Challenges for Brain Repair
Published in Frontiers in neuroscience (22-03-2022)“…[...]the regeneration process in zebrafish after brain damage is completely different from that observed in mammals. [...]microglial cells regulate neuronal…”
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15
Correction: Neurogenesis of medium spiny neurons in the nucleus accumbens continues into adulthood and is enhanced by pathological pain
Published in Molecular psychiatry (01-12-2021)Get full text
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Dynamic Changes in Ultrastructure of the Primary Cilium in Migrating Neuroblasts in the Postnatal Brain
Published in The Journal of neuroscience (11-12-2019)“…New neurons, referred to as neuroblasts, are continuously generated in the ventricular-subventricular zone of the brain throughout an animal's life. These…”
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Neurogenesis of medium spiny neurons in the nucleus accumbens continues into adulthood and is enhanced by pathological pain
Published in Molecular psychiatry (01-09-2021)“…In mammals, most adult neural stem cells (NSCs) are located in the ventricular–subventricular zone (V-SVZ) along the wall of the lateral ventricles and they…”
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18
Adult neurogenesis in the telencephalon of the lizard Podarcis liolepis
Published in Frontiers in neuroscience (23-02-2023)“…In adult lizards, new neurons are generated from neural stem cells in the ventricular zone of the lateral ventricles. These new neurons migrate and integrate…”
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19
Nanohybrid for Photodynamic Therapy and Fluorescence Imaging Tracking without Therapy
Published in Chemistry of materials (12-06-2018)“…Theranostic upconversion nanoparticles (UCNPs) are ideal candidates for personalized medicine. We present a smart, easy-to-prepare nanohybrid (NH) suitable for…”
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Neuraminidase inhibition promotes the collective migration of neurons and recovery of brain function
Published in EMBO molecular medicine (14-06-2024)“…In the injured brain, new neurons produced from endogenous neural stem cells form chains and migrate to injured areas and contribute to the regeneration of…”
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