Search Results - "Pérez, Janice M. J"

Thermal Unfolding of a Llama Antibody Fragment:  A Two-State Reversible Process by Pérez, Janice M. J, Renisio, Jean G, Prompers, Jeanine J, van Platerink, Chris J, Cambillau, Christian, Darbon, Hervé, Frenken, Leon G. J

“…Camelids produce functional “heavy chain” antibodies which are devoid of light chains and CH1 domains [Hamers-Casterman, C., et al. (1993) Nature 363,…”
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The new anticancer drug [(2R)-aminomethylpyrrolidine](1, 1-cyclobutanedicarboxylato)platinum(II) and its toxic S enantiomer do interact differently with nucleic acids by Bloemink, M J, Pérez, J M, Heetebrij, R J, Reedijk, J

“…The interaction of the two chiral isomers of the new anticancer agent [Pt(ampyr)(cbdca)] (ampyr=aminomethylpyrrolidine, cbdca=cyclobutanedicarboxylate) with…”
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Induced refolding of a temperature denatured llama heavy-chain antibody fragment by its antigen by Dolk, Edward, van Vliet, Cees, Perez, Janice M.J., Vriend, Gert, Darbon, Hervé, Ferrat, Gilles, Cambillau, Christian, Frenken, Leon G.J., Verrips, Theo

“…In a previous study we have shown that llama VHH antibody fragments are able to bind their antigen after a heat shock of 90°C, in contrast to the murine…”
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The solution structure of the guanine nucleotide exchange domain of human elongation factor 1β reveals a striking resemblance to that of EF-Ts from Escherichia coli by Pérez, Janice MJ, Siegal, Gregg, Kriek, Jan, Hård, Karl, Dijk, Jan, Canters, Gerard W, Möller, Wim

“…Background: In eukaryotic protein synthesis, the multi-subunit elongation factor 1 (EF-1) plays an important role in ensuring the fidelity and regulating the…”
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