Search Results - "Pérez, J. Eduardo"
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Accessibility Design Issues beyond the Standards of Government e-Services for People with Low Vision
Published in International journal of human-computer interaction (01-10-2024)“…Governments have been investing considerable resources into making their services to citizens available through the Internet. However, people face barriers…”
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Characterization of a new molecule capable of inhibiting several steps of the amyloid cascade in Alzheimer's disease
Published in Neurobiology of disease (01-07-2020)“…Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder in elderly people. Existent therapies are directed at alleviating some symptoms, but…”
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Effect of Cholesterol on Membrane Fluidity and Association of Aβ Oligomers and Subsequent Neuronal Damage: A Double-Edged Sword
Published in Frontiers in aging neuroscience (03-08-2018)“…The beta-amyloid peptide (Aβ) involved in Alzheimer's disease (AD) has been described to associate/aggregate on the cell surface disrupting the membrane…”
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Translation and validation of the abbreviated Prefrontal Symptoms Inventory ( PSI ‐20): A tool for assessing prefrontal symptoms in English‐speaking populations
Published in Journal of neuropsychology (10-10-2024)“…Abstract This study introduces the translation and validation of the Prefrontal Symptoms Inventory (PSI) into English, aiming to provide an ecologically valid…”
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MADRID+90 study on factors associated with longevity: Study design and preliminary data
Published in PloS one (17-05-2021)“…The progressive aging of the population represents a challenge for society. In particular, a strong increase in the number of people over 90 is expected in the…”
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The Stimulatory Effects of Intracellular α-Synuclein on Synaptic Transmission Are Attenuated by 2-Octahydroisoquinolin-2(1H)-ylethanamine
Published in International journal of molecular sciences (09-12-2021)“…α-Synuclein (αSyn) species can be detected in synaptic boutons, where they play a crucial role in the pathogenesis of Parkinson's Disease (PD). However, the…”
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Clinical validation of the Allen's Cognitive Level Screen in acquired brain injury
Published in Brain injury (12-05-2022)“…The evaluation of functional cognition is a central concern in clinical practice. However, there are few standardized or validated tools, and many of them take…”
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Impulsivity-Compulsivity Axis: Evidence of Its Clinical Validity to Individually Classify Subjects on the Use/Abuse of Information and Communication Technologies
Published in Frontiers in psychology (06-04-2021)“…The compulsive habit model proposed by Everitt and Robbins has accumulated important empirical evidence. One of their proposals is the existence of an axis, on…”
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The UPPS model of impulsivity in the abuse of Information and Communication Technologies (ICT)
Published in Adicciones (Palma de Mallorca) (01-09-2022)“…The UPPS model of impulsivity has recently been proposed, has been widely applied to substance abuse and is one of those recommended in the context of Research…”
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Boldine Attenuates Synaptic Failure and Mitochondrial Deregulation in Cellular Models of Alzheimer's Disease
Published in Frontiers in neuroscience (19-02-2021)“…Alzheimer's disease (AD) is the most common cause of senile dementia worldwide, characterized by both cognitive and behavioral deficits. Amyloid beta peptide…”
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Gabapentin Inhibits Multiple Steps in the Amyloid Beta Toxicity Cascade
Published in ACS chemical neuroscience (07-10-2020)“…Oligomeric β-amyloid peptide (Aβ) is one of the main neurotoxic agents of Alzheimer’s disease (AD). Oligomers associate to neuronal membranes, forming…”
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Smartphone Nonusers: Associated Sociodemographic and Health Variables
Published in Cyberpsychology, behavior and social networking (01-09-2019)“…Smartphone abuse and the associated consequences have been intensely studied. However, little attention has been given to the group of people who have a…”
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Obsession and compulsion in mobile phone use/abuse: OCDUS-ICT
Published in Adicciones (Palma de Mallorca) (31-03-2021)“…Compulsiveness has been considered one of the core characteristics of addictive behaviours. One of the abusive behaviours that has acquired importance in…”
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Single-embryo RNA sequencing for continuous and sex-specific gene expression analysis on Drosophila
Published in STAR protocols (15-09-2023)“…Exploring early embryonic gene expression is challenging due to the rate of development and the limited material available. Here, we present a protocol for…”
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Information and Communications Technologies (ICT): Problematic use of Internet, video games, mobile phones, instant messaging and social networks using MULTICAGE-TIC
Published in Adicciones (Palma de Mallorca) (01-01-2018)“…Use/abuse of Information and Communications Technologies (ICT) has in recent years become a topic of great interest. Current discussion addresses whether it…”
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The Level of NMDA Receptor in the Membrane Modulates Amyloid-β Association and Perforation
Published in Journal of Alzheimer's disease (22-06-2016)“…Alzheimer's disease is a neurodegenerative disorder that affects mostly the elderly. The main histopathological markers are the senile plaques formed by…”
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Polyunsaturated Fatty Acid Biosynthesis Involving Δ8 Desaturation and Differential DNA Methylation of FADS2 Regulates Proliferation of Human Peripheral Blood Mononuclear Cells
Published in Frontiers in immunology (05-03-2018)“…Polyunsaturated fatty acids (PUFAs) are important for immune function. Limited evidence indicates that immune cell activation involves endogenous PUFA…”
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Opiate drug use in the city of Madrid: Associated health and sociodemographic factors
Published in Adicciones (Palma de Mallorca) (01-01-2021)“…The use of opiate analgesics has led to a health and social emergency in the United States. In Spain, according to official data, the prescription of these…”
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Methadone dosage and its relationship to quality of life, satisfaction, psychopathology, cognitive performance and additional consumption of non-prescribed drugs
Published in Adicciones (Palma de Mallorca) (01-01-2017)“…The effectiveness of methadone maintenance treatment is beyond any doubt, but there remains some incertitude about the appropriate and effective dosage and the…”
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Validation of a cognitive complaints questionnaire for young adults: the relation between subjective memory complaints, prefrontal symptoms and perceived stress
Published in Revista de neurologiá (01-02-2012)“…Although subjective memory complaints are one of the most common causes behind visits to health services, there are hardly any validated instruments in Spanish…”
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