Search Results - "Péhourcq, F."
-
1
High-performance liquid chromatographic method with diode array detection to identify and quantify atypical antipsychotics and haloperidol in plasma after overdose
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05-05-2003)“…For toxicological purposes, an HPLC assay was developed for the simultaneous determination of haloperidol and atypical antipsychotics (risperidone,…”
Get full text
Journal Article -
2
Rapid high-performance liquid chromatographic measurement of amisulpride in human plasma: application to manage acute intoxication
Published in Journal of chromatography. B (05-06-2003)“…Amisulpride, a substituted benzamide derivative, is a second-generation (atypical) antipsychotic and is effective as maintenance therapy in patients with…”
Get full text
Journal Article Conference Proceeding -
3
Determination of third-generation cephalosporins by high-performance liquid chromatography in connection with pharmacokinetic studies
Published in Journal of Chromatography A (03-07-1998)“…The third-generation cephalosporins are semisynthetic β-lactam antibiotics, including several oral and parenteral agents with extended activity against…”
Get full text
Book Review Journal Article -
4
Piroxicam concentrations in plasma and synovial fluid after a single dose of piroxicam-beta-cyclodextrin
Published in International journal of clinical pharmacology and therapeutics (01-01-2001)“…The efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) in rheumatic diseases depends on their concentrations within the joint. We determined piroxicam…”
Get more information
Journal Article -
5
Direct injection HPLC micro method for the determination of voriconazole in plasma using an internal surface reversed-phase column
Published in Biomedical chromatography (01-11-2004)“…A direct plasma injection liquid chromatographic method has been developed for the determination of a new triazole antifungal agent, voriconazole, using an…”
Get full text
Journal Article -
6
Rapid high-performance liquid chromatographic measurement of buspirone in human plasma after overdose
Published in Biomedical chromatography (01-11-2004)“…For toxicological purposes, a rapid reversed‐phase high‐performance liquid chromatographic method was developed for the determination of the anxiolytic drug,…”
Get full text
Journal Article -
7
Clinical pharmacokinetics of low-dose pulse methotrexate in rheumatoid arthritis
Published in Clinical pharmacokinetics (01-03-1996)“…Low-dose pulse methotrexate has emerged as one of the most frequently used slow-acting, symptom-modifying antirheumatic drugs in patients with rheumatoid…”
Get full text
Journal Article -
8
Chiral resolution of flurbiprofen and ketoprofen enantiomers by HPLC on a glycopeptide-type column chiral stationary phase
Published in Biomedical chromatography (01-05-2001)“…Vancomycin is an amphoteric, glycopeptide, macrocyclic antibiotic. When attached to 5 µspherical silica gel, vancomycin proved to be an effective…”
Get full text
Journal Article -
9
Fat distribution in obese women is associated with subtle alterations of the hypothalamic-pituitary-adrenal axis activity and sensitivity to glucocorticoids
Published in Clinical endocrinology (Oxford) (01-10-2001)“…OBJECTIVES Obesity with abdominal body fat distribution (A‐BFD) and hypothalamic‐pituitary‐adrenal (HPA) axis activity are somehow linked, but the exact…”
Get full text
Journal Article -
10
Benzodiazepines and hip fractures in elderly people: case-control study
Published in BMJ (24-03-2001)“…Abstract Objective: To determine whether benzodiazepines are associated with an increased risk of hip fracture. Design: Case-control study. Participants: All…”
Get full text
Journal Article -
11
Decreased pituitary sensitivity to glucocorticoids in endurance-trained men
Published in European journal of endocrinology (01-04-2001)“…Muscular exercise induces hypothalamo-pituitary-adrenal (HPA) axis activation and when regularly repeated, as in endurance training, leads to HPA axis…”
Get full text
Journal Article -
12
Single and multiple dose pharmacokinetics of acetaminophen (paracetamol) in polymedicated very old patients with rheumatic pain
Published in Journal of rheumatology (01-01-2001)“…OBJECTIVE: To determine whether multiple dosing of acetaminophen would result in drug accumulation in polymedicated elderly patients with rheumatic pain…”
Get full text
Journal Article -
13
Determination of mirtazapine and its demethyl metabolite in plasma by high-performance liquid chromatography with ultraviolet detection: Application to management of acute intoxication
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05-08-2002)“…Mirtazapine is a new centrally acting noradrenergic and specific serotonin antidepressant, with an active demethyl metabolite. For toxicological purposes, a…”
Get full text
Journal Article -
14
HPLC microdetermination of flurbiprofen enantiomers in plasma with a glycopeptide-type chiral stationary phase column
Published in Biomedical chromatography (01-06-2004)“…A rapid and stereospecific HPLC micromethod to quantify flurbiprofen enantiomers was developed. Both flurbiprofen enantiomers and indomethacin, used as internal…”
Get full text
Journal Article -
15
Simultaneous determination of four antipsychotic drugs in plasma by high-performance liquid chromatography: Application to management of acute intoxications
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05-10-2003)“…A specific reversed phase-high pressure liquid chromatography (RP-HPLC) method has been developed for the simultaneous determination of clozapine (CZP),…”
Get full text
Journal Article -
16
Influence of a polymeric formulation of ketoprofen on its diffusion into cerebrospinal fluid in rats
Published in Journal of pharmaceutical and biomedical analysis (01-03-2002)“…Poly( d,l)lactide nanocapsules (NCs) have been proposed as an alternative carrier for many drugs. We investigated the influence of this formulation on the…”
Get full text
Journal Article -
17
Comparison of patient questionnaires, medical records, and plasma assays in assessing exposure to benzodiazepines in elderly subjects
Published in Clinical pharmacology and therapeutics (01-06-2001)“…Objective Exposure in pharmacoepidemiologic studies can rely on various sources such as medical records, patient questionnaires, or plasma samples, which do…”
Get full text
Journal Article -
18
Pharmacokinetics in the elderly
Published in Revue des maladies respiratoires (01-06-2002)“…Physiological changes that occur in the aging process may directly affect drug pharmacokinetics. In the absence of disease or other pathologic conditions,…”
Get more information
Journal Article -
19
(S)‐ketoprofen accumulation in premature neonates with renal failure who were exposed to the racemate during pregnancy
Published in British journal of clinical pharmacology (01-04-1999)Get full text
Journal Article -
20
In vitro distribution of ketoprofen enantiomers in articular tissues of osteoarthritic patients
Published in Journal of pharmaceutical and biomedical analysis (01-12-2001)“…The distribution of ketoprofen enantiomers in joint tissues was studied as a function of their relative tissular affinities using the multi-chamber…”
Get full text
Journal Article