Search Results - "Péguet‐Navarro, Josette"

Human C3 Deficiency Associated with Impairments in Dendritic Cell Differentiation, Memory B Cells, and Regulatory T Cells by Ghannam, Arije, Pernollet, Martine, Fauquert, Jean-Luc, Monnier, Nicole, Ponard, Denise, Villiers, Marie-Bernadette, Peguet-Navarro, Josette, Tridon, Arlette, Lunardi, Joel, Gerlier, Denis, Drouet, Christian

“…Primary C3 deficiency, a rare autosomal inherited disease (OMIM 120700), was identified in a 2-year-old male suffering from recurrent pyogenic infections from…”
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Gangliosides from Human Melanoma Tumors Impair Dendritic Cell Differentiation from Monocytes and Induce Their Apoptosis by Peguet-Navarro, Josette, Sportouch, Myriam, Popa, Iuliana, Berthier, Odile, Schmitt, Daniel, Portoukalian, Jacques

“…Gangliosides are ubiquitous membrane-associated glycosphingolipids, which are involved in cell growth and differentiation. Most tumor cells synthesize and shed…”
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Melanoma-derived gangliosides impair migratory and antigen-presenting function of human epidermal Langerhans cells and induce their apoptosis by Bennaceur, Karim, Popa, Iuliana, Portoukalian, Jacques, Berthier-Vergnes, Odile, Péguet-Navarro, Josette

“…Gangliosides are ubiquitous, membrane-associated, glycosphingolipids, the composition and production of which is altered in many tumour cells. They have been…”
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UV Radiation Induces the Epidermal Recruitment of Dendritic Cells that Compensate for the Depletion of Langerhans Cells in Human Skin by Achachi, Amine, Vocanson, Marc, Bastien, Philippe, Péguet-Navarro, Josette, Grande, Sophie, Goujon, Catherine, Breton, Lionel, Castiel-Higounenc, Isabelle, Nicolas, Jean- François, Gueniche, Audrey

“…UVR causes skin injury and inflammation, resulting in impaired immune function and increased skin cancer risk. Langerhans cells (LCs), the immune sentinels of…”
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Differential capacity of human skin dendritic cells to polarize CD4+ T cells into IL-17, IL-21 and IL-22 producing cells by Penel-Sotirakis, Karine, Simonazzi, Elise, Péguet-Navarro, Josette, Rozières, Aurore

“…Accumulating evidence suggests a contribution of T cell-derived IL-17, IL-21 and IL-22 cytokines in skin immune homeostasis as well as inflammatory disorders…”
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TNF-α enhances phenotypic and functional maturation of human epidermal Langerhans cells and induces IL-12 p40 and IP-10/CXCL-10 production by Berthier-Vergnes, Odile, Bermond, Fabienne, Flacher, Vincent, Massacrier, Catherine, Schmitt, Daniel, Péguet-Navarro, Josette

“…Dendritic cells (DC) play a central role in immunity/tolerance decision, depending on their activation/maturation state. TNF-α is largely produced in the skin…”
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Different mechanisms are involved in apoptosis induced by melanoma gangliosides on human monocyte-derived dendritic cells by Bennaceur, Karim, Popa, Iuliana, Chapman, Jessica Alice, Migdal, Camille, Péguet-Navarro, Josette, Touraine, Jean-Louis, Portoukalian, Jacques

“…Tumor escape is linked to multiple mechanisms, notably the liberation, by tumor cells, of soluble factors that inhibit the function of dendritic cells (DC). We…”
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Human Langerhans Cells Are More Efficient Than CD14−CD1c+ Dermal Dendritic Cells at Priming Naive CD4+ T Cells by Furio, Laetitia, Briotet, Isabelle, Journeaux, Alexandra, Billard, Hermine, Péguet-Navarro, Josette

“…Few data are available regarding the role of human skin dendritic cells (DCs) in driving T-cell responses. In this study we analyzed the relative capacity of…”
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Human epidermal Langerhans cells express the mannose‐fucose binding receptor by Condaminet, Bruno, Péguet‐Navarro, Josette, Stahl, Philip D., Dalbiez‐Gauthier, Catherine, Schmitt, Daniel, Berthier‐Vergnes, Odile

“…Sugar receptors are being increasingly implicated in host‐pathogen interactions because of their specific recognition of carbohydrates of microorganisms. The…”
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Poly(I:C)-Treated Human Langerhans Cells Promote the Differentiation of CD4+ T Cells Producing IFN-γ and IL-10 by Furio, Laetitia, Billard, Hermine, Valladeau, Jenny, Péguet-Navarro, Josette, Berthier-Vergnes, Odile

“…Epidermal Langerhans cells (LCs) are the first dendritic cells to encounter skin pathogens. However, their function has recently been challenged, especially in…”
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Expression and function of B7-1 (CD80) and B7-2 (CD86) on human epidermal Langerhans cells by Rattis, F M, Péguet-Navarro, J, Staquet, M J, Dezutter-Dambuyant, C, Courtellemont, P, Redziniak, G, Schmitt, D

“…In addition to T cell receptor triggering, activation of T cells requires costimulatory signals that have been shown to be mainly initiated through CD28. We…”
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Binding and in vitro modulation of human epidermal Langerhans cell functions by substance P by STANIEK, V, MISERY, L, PEGUET-NAVARRO, J, ABELLO, J, DOUTREMEPUICH, J.-D, CLAUDY, A, SCHMITT, D

“…Substance P (SP) is distributed in both the central and peripheral nervous system. It has various effects on immunocompetent cells, such as macrophages and…”
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Differential Capacity of Human Skin Dendritic Cells to Polarize CD4.sup.+T Cells into IL-17, IL-21 and IL-22 Producing Cells by Penel-Sotirakis, Karine, Simonazzi, Elise, Péguet-Navarro, Josette, Rozières, Aurore

“…Accumulating evidence suggests a contribution of T cell-derived IL-17, IL-21 and IL-22 cytokines in skin immune homeostasis as well as inflammatory disorders…”
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cis-urocanic acid failed to affect in vitro human Langerhans cell allostimulatory function by Rattis, F M, Péguet-Navarro, J, Courtellemont, P, Redziniak, G, Schmitt, D

“…Urocanic acid (UCA) represents the major ultraviolet B (UVB, 290-320 nm)-absorbing component of the skin. Trans-UCA is naturally produced in the stratum…”
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Differential toxicity on monocytes and monocyte-derived dendritic Cells: a new tool to differentiate allergens from irritants? by Furio, Laetitia, Guesnet, Joelle, Ducarre, Blandine, Guezennec, Anne, Schmitt, Daniel, Peguet-Navarro, Josette

“…Phenotypic activation of monocyte‐derived dendritic cells has been proposed as an in vitro alternative assay to discriminate potential sensitizers from…”
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Poly(I:C)-Treated Human Langerhans Cells Promote the Differentiation of CD4+ T Cells Producing IFN-[gamma] and IL-10 by Furio, Laetitia, Billard, Hermine, Valladeau, Jenny, Péguet-navarro, Josette, Berthier-vergnes, Odile

“…Epidermal Langerhans cells (LCs) are the first dendritic cells to encounter skin pathogens. However, their function has recently been challenged, especially in…”
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Human C3 deficiency associated with impairments in dendritic cell differentiation, memory B cells, and regulatory T cells by Ghannam, Arije, Pernollet, Martine, Fauquert, Jean-Luc, Monnier, Nicole, Ponard, Denise, Villiers, Marie-Bernadette, Péguet-Navarro, Josette, Tridon, Arlette, Lunardi, Joël, Gerlier, Denis, Drouet, Christian

“…Primary C3 deficiency, a rare autosomal inherited disease (OMIM 120700), was identified in a 2-year-old male suffering from recurrent pyogenic infections from…”
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Melanoma-derived gangliosides impair migratory and antigen-presenting function of human epidermal Langerhans cells and induce their apoptosis: Gangliosides impair Langerhans cell function by Bennaceur, Karim, Bennaceur, Karim, Popa, Iuliana, Portoukalian, Jacques, Berthier-Vergnes, Odile, Péguet-Navarro, Josette

“…Gangliosides are ubiquitous, membrane-associated, glycosphingolipids, the composition and production of which is altered in many tumour cells. They have been…”
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Interleukin-10 inhibits the primary allogeneic T cell response to human epidermal Langerhans cells by Péguet-Navarro, J, Moulon, C, Caux, C, Dalbiez-Gauthier, C, Banchereau, J, Schmitt, D

“…In this study, we analyzed the effect of interleukin-10 (IL-10) on the primary allogeneic T cell response induced by human Langerhans cells (LC), the dendritic…”
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Effects of Ultraviolet B Radiation on Human Langerhans Cells: Functional Alteration of CD86 Upregulation and Induction of Apoptotic Cell Death by Rattis, Frédérique-Marie, Concha, Miguel, Dalbiez-Gauthier, Catherine, Schmitt, Daniel, Péguet-Navarro, Josette, Courtellemont, Pascal

“…We have recently reported that in vitro low dose of ultraviolet B radiation (UVB, 100–200 J per m2) directly impaired the antigen-presenting function of human…”
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