Search Results - "Pébay, A"

Decreased anti-regenerative effects after spinal cord injury in spry4− / − mice by Goldshmit, Y, Frisca, F, Kaslin, J, Pinto, A.R, Tang, J.-K.K.Y, Pébay, A, Pinkas-Kramarski, R, Currie, P.D

“…Highlights • spry4 −/− mice exhibit reduced inflammatory response after spinal cord injury. • spry4 −/− mice exhibit reduced astrogliosis after spinal cord…”
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S3.5 Induction of neural crest stem cells from human ES-derived neural progenitor cells: Migration and differentiation in avian embryos and explants of embryonic mouse gut by Newgreen, D.F, Hotta, R, Pepdjonovic, L, Anderson, R.B, Zhang, D, Bergner, A.J, Leung, J, Pébay, A, Young, H.M, Dottori, M

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Antiproliferative properties of sphingosine-1-phosphate in human hepatic myofibroblasts by Pébay, A, Toutant, M, Prémont, J, Calvo, C F, Venance, L, Cordier, J, Glowinski, J, Tencé, M

“…Sphingosine-1-phosphate (S1P) is a potent lysophospholipid mediator mostly released by activated platelets. It is involved in several functions in peripheral…”
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Stem cells in reparing optic nerve damage by Pebay, A., Gill, K., Needham, K., van Bergen, N., Lim, S., Hernandez, D., Liang, H., Kearns, L., Hung, S., Hewitt, A., Mackey, D., Trounce, I., Wong, R.

“…Summary Modelling Leber's Hereditary Optic neuropathy using human induced pluripotent stem cells. Human induced pluripotent stem cells (iPSCs) provide an…”
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Sphingosine-1-phosphate induces proliferation of astrocytes: regulation by intracellular signalling cascades by Pébay, Alice, Toutant, Madeleine, Prémont, Joël, Calvo, Charles-Félix, Venance, Laurent, Cordier, Jocelyne, Glowinski, Jacques, Tencé, Martine

“…Sphingosine‐1‐phosphate (S1P) is a potent lysophospholipid mediator mostly released by activated platelets. It is involved in several functions in peripheral…”
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Pleiotropic effects of lysophosphatidic acid on striatal astrocytes by Pébay, Alice, Torrens, Yvette, Toutant, Madeleine, Cordier, Jocelyne, Glowinski, Jacques, Tencé, Martine

“…Lysophosphatidic acid (LPA) is a potent lipid mediator that is likely involved in diverse functions in the brain. Several recent studies have suggested that…”
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PSEN1ΔE9, APPswe, and APOE4 Confer Disparate Phenotypes in Human iPSC-Derived Microglia by Konttinen, Henna, Cabral-da-Silva, Mauricio e Castro, Ohtonen, Sohvi, Wojciechowski, Sara, Shakirzyanova, Anastasia, Caligola, Simone, Giugno, Rosalba, Ishchenko, Yevheniia, Hernández, Damián, Fazaludeen, Mohammad Feroze, Eamen, Shaila, Budia, Mireia Gómez, Fagerlund, Ilkka, Scoyni, Flavia, Korhonen, Paula, Huber, Nadine, Haapasalo, Annakaisa, Hewitt, Alex W., Vickers, James, Smith, Grady C., Oksanen, Minna, Graff, Caroline, Kanninen, Katja M., Lehtonen, Sarka, Propson, Nicholas, Schwartz, Michael P., Pébay, Alice, Koistinaho, Jari, Ooi, Lezanne, Malm, Tarja

“…Here we elucidate the effect of Alzheimer disease (AD)-predisposing genetic backgrounds, APOE4, PSEN1ΔE9, and APPswe, on functionality of human microglia-like…”
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Patient-specific iPSCs Reveal Vascular Dysfunction in Friedreich Ataxia by Lees, J., Zhang, N., Kong, A., Treller, A., Mitchell, G., Dottori, M., Pebay, A., Wilcox, S., Chong, M., Peverill, R., Delatyki, M., Pullin, J., McCarthy, D., Napierala, M., Lim, S.

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Particulate matter from car exhaust alters function of human iPSC-derived microglia by Jäntti, Henna, Jonk, Steffi, Gómez Budia, Mireia, Ohtonen, Sohvi, Fagerlund, Ilkka, Fazaludeen, Mohammad Feroze, Aakko-Saksa, Päivi, Pebay, Alice, Lehtonen, Šárka, Koistinaho, Jari, Kanninen, Katja M, Jalava, Pasi I, Malm, Tarja, Korhonen, Paula

“…Air pollution is recognized as an emerging environmental risk factor for neurological diseases. Large-scale epidemiological studies associate traffic-related…”
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Essential Roles of Sphingosine‐1‐Phosphate and Platelet‐Derived Growth Factor in the Maintenance of Human Embryonic Stem Cells by Pébay, Alice, Wong, Raymond C.B., Pitson, Stuart M., Wolvetang, Ernst J., Peh, Gary S.‐L., Filipczyk, Adam, Koh, Karen L.L., Tellis, Irene, Nguyen, Linh T.V., Pera, Martin F.

“…Human embryonic stem cells (hESCs) have great potential for use in research and regenerative medicine, but very little is known about the factors that maintain…”
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S1P inhibits gap junctions in astrocytes: involvement of G and Rho GTPase/ROCK by Rouach, Nathalie, Pébay, Alice, Même, William, Cordier, Jocelyne, Ezan, Pascal, Etienne, Eric, Giaume, Christian, Tencé, Martine

“…Sphingosine-1-phosphate (S1P) is a potent and pleiotropic bioactive lysophospholipid mostly released by activated platelets that acts on its target cells…”
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Moderated Poster session - Genetic, Epigenetic & Integrative480Inhibiting mitochondrial fission with Mdivi-1 directs cardiac differentiation of human induced pluripotent stem cells via protein kinase CK2481A novel role of tristetraprolin in preventing mitochondrial dysfunction in the heart against iron deficiency by optimizing expression of Rieske iron-sulfur protein482Different therapeutic approaches to downregulate the activation of the hepatic interleukin-6/stat3/complement pathway in two mod by Lim, S, Sato, T, Marino, F, Stillitano, F, Pioner, JM, Haase, T, Pianezzi, E, Sivakumaran, P, Hernandez, D, Wong, RCB, Taylor, C, Dusting, G, Pebay, A, Bayeva, M, Chang, HC, Shapiro, JS, Yar, S, Ardehali, H, Camporeale, A, Avalle, L, Heymans, S, Roman, B, Kotelianski, V, Poli, V, Karakikes, I, Nonnenmacher, M, Ceholski, D, Zhang, L, Hulot, JS, Cai, CL, Kranias, EG, Hajjar, RJ, Racca, AW, Klaiman, JM, Guan, X, Pabon, L, Muskheli, V, Macadangdang, J, Kim, DH, Mack, DL, Childers, MK, Tesi, C, Poggesi, C, Murry, CE, Regnier, M, Krause, J, Mueller, C, Stenzig, J, Roethemeier, C, Wild, PS, Blankenberg, S, Zeller, T, Altomare, C, Cervio, E, Bolis, S, Moccetti, T, Camici, GG, Barile, L, Vassalli, GG

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Study of gap junctions in human embryonic stem cells by Wong, Raymond C B, Pébay, Alice

“…Gap junctional intercellular communication (GJIC) has been described in different cell types including stem cells and has been involved in different biological…”
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Gap junctions modulate apoptosis and colony growth of human embryonic stem cells maintained in a serum-free system by Wong, Raymond C.B., Dottori, Mirella, Koh, Karen L.L., Nguyen, Linh T.V., Pera, Martin F., Pébay, Alice

“…We investigated the gap junctional properties of human embryonic stem cells (hESC) cultivated in a serum-free system using sphingosine-1-phosphate and…”
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Presence of Functional Gap Junctions in Human Embryonic Stem Cells by Wong, Raymond C.B., Pébay, Alice, Nguyen, Linh T.V., Koh, Karen L.L., Pera, Martin F.

“…Gap junctions are intercellular channels that allow both chemical and electrical signaling between two adjacent cells. Gap junction intercellular communication…”
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Human trait of microglia: iPSC-derived microglia in modeling microglial functions by Konttinen, H, Cabral-Da-Silva, MEC, Ohtonen, S, Shakirzyanova, A, Ishchenko, Y, Caligola, S, Giugno, R, Hernandez, D, Fazaludeen, F, Eamen, S, Fagerlund, I, Scoyni, F, Wojciechowski, S, Huber, N, Haapasalo, A, Oksanen, M, Propson, N, Schwartz, MP, Graff, C, Lehtonen, S, Kanninen, K, Pebay, A, Koistinaho, J, Ooi, L, Malm, TM

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A Role for Neurotrophins in Embryonic Stem Cell Growth by Trounson, Alan, Pebay, Alice

“…Neurotrophins act on embryonic cells through TRK receptors to inhibit apoptosis by phosphorylation of AKT. In a recent paper in Nature Biotechnology, Pyle et…”
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Sphingosine-1-phosphate induces proliferation of astrocytes: regulation by intracellular signalling cascades

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