Search Results - "Pål Aukrust"

Visfatin/NAMPT: A Multifaceted Molecule with Diverse Roles in Physiology and Pathophysiology by DAHL, Tuva B, HOLM, Sverre, AUKRUST, Pal, HALVORSEN, Bente

“…Visfatin/NAMPT (nicotinamide phosphoribosyltransferase) is a protein with several suggested functions. Although the first discovery of this molecule as a…”
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Impact of Systemic Inflammation on the Progression of Gestational Diabetes Mellitus by Lekva, Tove, Norwitz, Errol R., Aukrust, Pål, Ueland, Thor

“…With increasing rates of obesity and new diagnostic criteria for gestational diabetes mellitus (GDM), the overall prevalence of GDM is increasing worldwide…”
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Low CETP activity and unique composition of large VLDL and small HDL in women giving birth to small-for-gestational age infants by Roland, Marie Cecilie Paasche, Godang, Kristin, Aukrust, Pål, Henriksen, Tore, Lekva, Tove

“…Cholesteryl ester transfer protein (CETP) regulates high density lipoproteins (HDL)-cholesterol (C) and HDL-C is essential for fetal development. We…”
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Randomized Trial of Interleukin-6 Receptor Inhibition in Patients With Acute ST-Segment Elevation Myocardial Infarction by Broch, Kaspar, Anstensrud, Anne Kristine, Woxholt, Sindre, Sharma, Kapil, Tøllefsen, Ingvild Maria, Bendz, Bjørn, Aakhus, Svend, Ueland, Thor, Amundsen, Brage Høyem, Damås, Jan Kristian, Berg, Erlend Sturle, Bjørkelund, Elisabeth, Bendz, Christina, Hopp, Einar, Kleveland, Ola, Stensæth, Knut Haakon, Opdahl, Anders, Kløw, Nils-Einar, Seljeflot, Ingebjørg, Andersen, Geir Øystein, Wiseth, Rune, Aukrust, Pål, Gullestad, Lars

“…Prompt myocardial revascularization with percutaneous coronary intervention (PCI) reduces infarct size and improves outcomes in patients with ST-segment…”
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Inflammatory cytokines in heart failure: mediators and markers by Gullestad, Lars, Ueland, Thor, Vinge, Leif Erik, Finsen, Alexandra, Yndestad, Arne, Aukrust, Pål

“…Evidence from both experimental and clinical trials indicates that inflammatory mediators are of importance in the pathogenesis of chronic heart failure (HF)…”
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The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls by Kummen, Martin, Holm, Kristian, Anmarkrud, Jarl Andreas, Nygård, Ståle, Vesterhus, Mette, Høivik, Marte L, Trøseid, Marius, Marschall, Hanns-Ulrich, Schrumpf, Erik, Moum, Bjørn, Røsjø, Helge, Aukrust, Pål, Karlsen, Tom H, Hov, Johannes R

“…Gut microbiota could influence gut, as well as hepatic and biliary immune responses. We therefore thoroughly characterised the gut microbiota in primary…”
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Systemic complement activation is associated with respiratory failure in COVID-19 hospitalized patients by Holter, Jan C., Pischke, Soeren E., de Boer, Eline, Lind, Andreas, Jenum, Synne, Holten, Aleksander R., Tonby, Kristian, Barratt-Due, Andreas, Sokolova, Marina, Schjalm, Camilla, Chaban, Viktoriia, Kolderup, Anette, Tran, Trung, Gjølberg, Torleif Tollefsrud, Skeie, Linda G., Hesstvedt, Liv, Ormåsen, Vidar, Fevang, Børre, Austad, Cathrine, Müller, Karl Erik, Fladeby, Cathrine, Holberg-Petersen, Mona, Halvorsen, Bente, Müller, Fredrik, Aukrust, Pål, Dudman, Susanne, Ueland, Thor, Andersen, Jan Terje, Lund-Johansen, Fridtjof, Heggelund, Lars, Dyrhol-Riise, Anne M., Mollnes, Tom E.

“…Respiratory failure in the acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is hypothesized to be driven by an overreacting innate immune…”
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Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19 by Aamodt, Anne Hege, Høgestøl, Einar August, Popperud, Trine Haug, Holter, Jan Cato, Dyrhol-Riise, Anne Ma, Tonby, Kristian, Stiksrud, Birgitte, Quist-Paulsen, Else, Berge, Tone, Barratt-Due, Andreas, Aukrust, Pål, Heggelund, Lars, Blennow, Kaj, Zetterberg, Henrik, Harbo, Hanne Flinstad

“…Objective To test the hypotheses that blood biomarkers for nervous system injury, serum concentrations of neurofilament light chain protein (NfL) and glial…”
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The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosis by Hovland, Anders, Jonasson, Lena, Garred, Peter, Yndestad, Arne, Aukrust, Pål, Lappegård, Knut T, Espevik, Terje, Mollnes, Tom E

“…Abstract Despite recent medical advances, atherosclerosis is a global burden accounting for numerous deaths and hospital admissions. Immune-mediated…”
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Autoimmunity and Inflammation in CVID: a Possible Crosstalk between Immune Activation, Gut Microbiota, and Epigenetic Modifications by Jørgensen, Silje F., Fevang, Børre, Aukrust, Pål

“…Common variable immunodeficiency (CVID) is the most common symptomatic primary immunodeficiency among adults and is characterized by a B cell dysfunction and…”
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Increased Secondary/Primary Bile Acid Ratio in Chronic Heart Failure by Mayerhofer, Cristiane C.K., Ueland, Thor, Broch, Kaspar, Vincent, Royce P., Cross, Gemma F., Dahl, Christen P., Aukrust, Pål, Gullestad, Lars, Hov, Johannes R., Trøseid, Marius

“…•In this cross-sectional study, we found decreased serum levels of primary bile acids and increased levels of specific secondary bile acids, resulting in…”
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Reduced Cardiac Function by Echocardiography in a Minority of COVID-19 Patients 3 Months after Hospitalization by Tangen, Jorun, Aukrust, Pål, Barratt-Due, Andreas, Skulstad, Helge, Edvardsen, Thor

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NLRP3 inflammasome mediates oxidative stress-induced pancreatic islet dysfunction by Sokolova, Marina, Sahraoui, Afaf, Høyem, Merete, Øgaard, Jonas, Lien, Egil, Aukrust, Pål, Yndestad, Arne, Ranheim, Trine, Scholz, Hanne

“…Inflammasomes are multiprotein inflammatory platforms that induce caspase-1 activation and subsequently interleukin (IL)-1β and IL-18 processing. The NLRP3…”
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NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis by Paramel Varghese, Geena, Folkersen, Lasse, Strawbridge, Rona J., Halvorsen, Bente, Yndestad, Arne, Ranheim, Trine, Krohg‐Sørensen, Kirsten, Skjelland, Mona, Espevik, Terje, Aukrust, Pål, Lengquist, Mariette, Hedin, Ulf, Jansson, Jan‐Håkan, Fransén, Karin, Hansson, Göran K., Eriksson, Per, Sirsjö, Allan

“…Background The NLR family, pyrin domain containing 3 (NLRP3) inflammasome is an interleukin (IL)‐1β and IL‐18 cytokine processing complex that is activated in…”
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Chemokines and Cardiovascular Risk by Aukrust, Pål, Halvorsen, Bente, Yndestad, Arne, Ueland, Thor, Øie, Erik, Otterdal, Kari, Gullestad, Lars, Damås, Jan K

“…Based on the importance of inflammation in atherogenesis, recent work has focused on whether plasma markers of inflammation can noninvasively diagnose and…”
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Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication by Lauritzen, Knut H, Olsen, Maria Belland, Ahmed, Mohammed Shakil, Yang, Kuan, Rinholm, Johanne Egge, Bergersen, Linda H, Esbensen, Qin Ying, Sverkeli, Lars Jansen, Ziegler, Mathias, Attramadal, Håvard, Halvorsen, Bente, Aukrust, Pål, Yndestad, Arne

“…Poly(ADP-ribose) polymerase (PARP) enzymes initiate (mt)DNA repair mechanisms and use nicotinamide adenine dinucleotide (NAD + ) as energy source. Prolonged…”
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Inflammatory cytokines as biomarkers in heart failure by Ueland, Thor, Gullestad, Lars, Nymo, Ståle H., Yndestad, Arne, Aukrust, Pål, Askevold, Erik T.

“…Inflammation has been implicated in the pathogenesis of heart failure (HF). In addition to their direct involvement as mediators in the pathogenesis of HF,…”
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Exploring the Wnt signaling pathway in schizophrenia and bipolar disorder by Hoseth, Eva Z., Krull, Florian, Dieset, Ingrid, Mørch, Ragni H., Hope, Sigrun, Gardsjord, Erlend S., Steen, Nils Eiel, Melle, Ingrid, Brattbakk, Hans-Richard, Steen, Vidar M., Aukrust, Pål, Djurovic, Srdjan, Andreassen, Ole A., Ueland, Thor

“…The Wnt signaling pathway plays a crucial role in neurodevelopment and in regulating the function and structure of the adult nervous system. Schizophrenia…”
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Decreased IL-1β-induced CCL20 response in human iPSC-astrocytes in schizophrenia: Potential attenuating effects on recruitment of regulatory T cells by Akkouh, Ibrahim A., Ueland, Thor, Hansson, Lars, Inderhaug, Elin, Hughes, Timothy, Steen, Nils Eiel, Aukrust, Pål, Andreassen, Ole A., Szabo, Attila, Djurovic, Srdjan

“…•IL-1β treatment results in impaired CCL20 responses in iPSC-astrocytes in SCZ.•Decreased IL-1β-induced CCL20 secretion by SCZ iPSC-astrocytes reduces Treg…”
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Distinct patterns of soluble leukocyte activation markers are associated with etiology and outcomes in precapillary pulmonary hypertension by Lekva, Tove, Gullestad, Lars, Broch, Kaspar, Aukrust, Pål, Andreassen, Arne K., Ueland, Thor

“…Activation of inflammatory processes has been identified as a major driver of pulmonary vascular remodeling that contributes to the development of precapillary…”
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