Search Results - "Pääkkönen, Kimmo"

The physical character of information by Karnani, Mahesh, Pääkkönen, Kimmo, Annila, Arto

“…The mathematical theory of communication defines information in syntax without reference to its physical representation and semantic significance. However, in…”
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Structural Insight into Dimeric Interaction of the SARAH Domains from Mst1 and RASSF Family Proteins in the Apoptosis Pathway by Hwang, Eunha, Ryu, Kyoung-Seok, Pääkkönen, Kimmo, Güntert, Peter, Cheong, Hae-Kap, Lim, Dae-Sik, Lee, Jie-Oh, Jeon, Young Ho, Cheong, Chaejoon

“…In eukaryotic cells, apoptosis and cell cycle arrest by the Ras → RASSF → MST pathway are controlled by the interaction of SARAH (for Salvador/Rassf/Hippo)…”
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Structural Basis of PxxDY Motif Recognition in SH3 Binding by Aitio, Olli, Hellman, Maarit, Kesti, Tapio, Kleino, Iivari, Samuilova, Olga, Pääkkönen, Kimmo, Tossavainen, Helena, Saksela, Kalle, Permi, Perttu

“…We have determined the solution structure of epidermal growth factor receptor pathway substrate 8 (Eps8) L1 Src homology 3 (SH3) domain in complex with the…”
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Solution structures of the first and fourth TSR domains of F-spondin by Pääkkönen, Kimmo, Tossavainen, Helena, Permi, Perttu, Rakkolainen, Harri, Rauvala, Heikki, Raulo, Erkki, Kilpeläinen, Ilkka, Güntert, Peter

“…F‐spondin is a protein mainly associated with neuronal development. It attaches to the extracellular matrix and acts in the axon guidance of the developing…”
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Solution structure of the GUCT domain from human RNA helicase II/Guβ reveals the RRM fold, but implausible RNA interactions by Ohnishi, Satoshi, Pääkkönen, Kimmo, Koshiba, Seizo, Tochio, Naoya, Sato, Manami, Kobayashi, Naohiro, Harada, Takushi, Watanabe, Satoru, Muto, Yutaka, Güntert, Peter, Tanaka, Akiko, Kigawa, Takanori, Yokoyama, Shigeyuki

“…Human RNA helicase II/Guα (RH‐II/Guα) and RNA helicase II/Guβ (RH‐II/Guβ) are paralogues that share the same domain structure, consisting of the DEAD box…”
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Quaternary Structure Built from Subunits Combining NMR and Small-Angle X-Ray Scattering Data by Mattinen, Maija-Liisa, Pääkkönen, Kimmo, Ikonen, Teemu, Craven, Jeremy, Drakenberg, Torbjörn, Serimaa, Ritva, Waltho, Jonathan, Annila, Arto

“…A new principle in constructing molecular complexes from the known high-resolution domain structures joining data from NMR and small-angle x-ray scattering…”
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Pharmacogenomics of clinical response to Natalizumab in multiple sclerosis: a genome-wide multi-centric association study by Clarelli, Ferdinando, Corona, Andrea, Pääkkönen, Kimmo, Sorosina, Melissa, Zollo, Alen, Piehl, Fredrik, Olsson, Tomas, Stridh, Pernilla, Jagodic, Maja, Hemmer, Bernhard, Gasperi, Christiane, Harroud, Adil, Shchetynsky, Klementy, Mingione, Alessandra, Mascia, Elisabetta, Misra, Kaalindi, Giordano, Antonino, Mazzieri, Maria Laura Terzi, Priori, Alberto, Saarela, Janna, Kockum, Ingrid, Filippi, Massimo, Esposito, Federica, Boneschi, Filippo Giovanni Martinelli

“…Background Inter-individual differences in treatment response are marked in multiple sclerosis (MS). This is true for Natalizumab (NTZ), to which a subset of…”
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On the Origin of Residual Dipolar Couplings from Denatured Proteins by Louhivuori, Martti, Pääkkönen, Kimmo, Fredriksson, Kai, Permi, Perttu, Lounila, Juhani, Annila, Arto

“…Effects of steric obstruction on random flight chains are examined. Spatial probability distributions are elaborated to calculate residual dipolar couplings…”
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Erratum to: NMR resonance assignment of DnaE intein from Nostoc punctiforme by Heinämäki, Kimmo, Oeemig, Jesper S., Pääkkönen, Kimmo, Djupsjöbacka, Janica, Iwaï, Hideo

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Alignment of chain-like molecules by Louhivuori, Martti, Fredriksson, Kai, Pääkkönen, Kimmo, Permi, Perttu, Annila, Arto

“…The steric obstruction model, that describes the enhanced alignment of folded proteins by anisotropic medium, is extended to account for the residual dipolar…”
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Impact of Genetic Susceptibility on Multiple Sclerosis Immune Methylome (S17.006) by Giordano, Antonino, Needhamsen, Maria, Shchetynsky, Klementy, Stridh, Pernilla, Harroud, Adil, Gasperi, Christiane, Zinevych, Iaroslav, Paakkonen, Kimmo, Lahermo, Paivi, D'Alfonso, Sandra, Barizzone, Nadia, Cavalla, Paola, Gallo, Antonio, Chinni, Elena, Hemmer, Bernhard, Flaskamp, Martina Clara, Uibel, Paula, Piehl, Fredrik, Esposito, Federica, Mascia, Elisabetta, Sorosina, Melissa, Filippi, Massimo, Gustavsen, Stefan, Olsson, Anna, Søndergaard, Helle Bach, Oturai, Annette, Dubois, Benedicte, Harbo, Hanne Catherine Flinstad, Berge, Tone, Bos, Steffan Daniel, Villoslada, Pablo, Llufriu, Sara, Boneschi, Filippo Martinelli, Liblau, Roland, Pignolet, Beatrice, Kockum, Ingrid, Beck, Stephan, Saarela, Janna, Jagodic, Maja

“…Abstract only…”
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NMR resonance assignment of DnaE intein from Nostoc punctiforme by Heinämäki, Kimmo, Oeemig, Jesper S, Djupsjöbacka, Janica, Iwaï, Hideo

“…DnaE intein from Nostoc punctiforme (Npu) is one of naturally occurring split inteins, which has robust protein splicing activity. Highly efficient…”
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Solution Structure and Main Chain Dynamics of the Regulatory Domain (Residues 1–91) of Human Cardiac Troponin C by Pääkkönen, Kimmo, Annila, Arto, Sorsa, Tia, Pollesello, Piero, Tilgmann, Carola, Kilpeläinen, Ilkka, Karisola, Piia, Ulmanen, Ismo, Drakenberg, Torbjörn

“…The three-dimensional structure of calcium-loaded regulatory, i.e. N-terminal, domain (1–91) of human cardiac troponin C (cNTnC) was determined by NMR in…”
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Conformations of the regulatory domain of cardiac troponin C examined by residual dipolar couplings by Pääkkönen, Kimmo, Sorsa, Tia, Drakenberg, Torbjörn, Pollesello, Piero, Tilgmann, Carola, Permi, Perttu, Heikkinen, Sami, Kilpeläinen, Ilkka, Annila, Arto

“…Conformations of the regulatory domain of cardiac troponin C (cNTnC) were studied by means of residual dipolar couplings measured from samples dissolved in…”
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