Search Results - "Pääkkö, Paavo K."

Adenovirus-Mediated Transfer of a Recombinant α1-Antitrypsin Gene to the Lung Epithelium in Vivo by Rosenfeld, Melissa A., Siegfried, Wolfgang, Yoshimura, Kunihiko, Yoneyama, Koichi, Fukayama, Masashi, Stier, Larue E., Pääkkö, Paavo K., Gilardi, Pascale, Stratford-Perricaudet, Leslie D., Perricaudet, Michel, Jallat, Sophie, Pavirani, Andrea, Lecocq, Jean-Pierre, Crystal, Ronald G.

“…The respiratory epithelium is a potential site for somatic gene therapy for the common hereditary disorders α1-antitrypsin (α1AT) deficiency and cystic…”
Get full text

Nitric oxide synthases are associated with bronchial dysplasia by Puhakka, Airi R.A., Harju, Terttu H., Pääkkö, Paavo K., Soini, Ylermi M., Kinnula, Vuokko L.

“…Recent studies suggest that reactive oxygen (ROS) and nitrogen species (RNS) are highly associated with the pathogenesis of cigarette smoke related lung…”
Get full text

Cell-specific regulation of gamma-glutamylcysteine synthetase in human interstitial lung diseases by Tiitto, Leena H, Peltoniemi, Mirva J, Kaarteenaho-Wiik, Riitta L, Soini, Ylermi M, Pääkkö, Paavo K, Sormunen, Raija T, Kinnula, Vuokko L

“…The pathogenesis of interstitial lung diseases (ILDs) is known to be associated with reactive oxygen and nitrogen metabolites and increased oxidant stress. One…”
Get full text

Expression of hyaluronan in normal and dysplastic bronchial epithelium and in squamous cell carcinoma of the lung by Pirinen, Risto T., Tammi, Raija H., Tammi, Markku I., Pääkkö, Paavo K., Parkkinen, Jyrki J., Ågren, Ulla M., Johansson, Risto T., Viren, Markku M. T., Törmänen, Ulla, Soini, Ylermi M. J., Kosma, Veli‐Matti

“…A series of 85 lung/bronchial tissue samples from 76 patients consisting of normal, metaplastic and dysplastic epithelium and different types of lung…”
Get full text

Expression of the Cystic Fibrosis Transmembrane Conductance Regulator Gene in the Respiratory Tract of Normal Individuals and Individuals with Cystic Fibrosis by Trapnell, Bruce C., Chu, Chin-Shyan, Paakko, Paavo K., Banks, Tyrone C., Yoshimura, Kunihiko, Ferrans, Victor J., Chernick, Milica S., Crystal, Ronald G.

“…The most common mutation of the cystic fibrosis transmembrane conductance regulator gene, CFTR, associated with the clinical disorder cystic fibrosis (CF) is…”
Get full text

Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo by Rosenfeld, M A, Siegfried, W, Yoshimura, K, Yoneyama, K, Fukayama, M, Stier, L E, Pääkkö, P K, Gilardi, P, Stratford-Perricaudet, L D, Perricaudet, M

“…The respiratory epithelium is a potential site for somatic gene therapy for the common hereditary disorders alpha 1-antitrypsin (alpha 1AT) deficiency and…”
Get full text