Search Results - "Pál, Gábor"

The emerging roles of mannose-binding lectin-associated serine proteases (MASPs) in the lectin pathway of complement and beyond by Dobó, József, Pál, Gábor, Cervenak, László, Gál, Péter

“…Summary Mannose‐binding lectin (MBL)‐associated serine proteases (MASPs) are the enzymatic constituents of the lectin pathway of the complement system. They…”
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Insights into the Influence of Different Pre-Treatments on Physicochemical Properties of Nafion XL Membrane and Fuel Cell Performance by Selim, Asmaa, Szijjártó, Gábor Pál, Tompos, András

“…Perfluorosulfonic acid (PFSA) polymers such as Nafion are the most frequently used Proton Exchange Membrane (PEM) in PEM fuel cells. Nafion XL is one of the…”
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Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2 by Héja, Dávid, Kocsis, Andrea, Dobó, József, Szilágyi, Katalin, Szász, Róbert, Závodszky, Péter, Pál, Gábor, Gál, Péter

“…The lectin pathway of complement activation is an important component of the innate immune defense. The initiation complexes of the lectin pathway consist of a…”
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MASP-1 of the complement system enhances clot formation in a microvascular whole blood flow model by Jenny, Lorenz, Dobó, József, Gál, Péter, Pál, Gábor, Lam, Wilbur A, Schroeder, Verena

“…The complement and coagulation systems closely interact with each other. These interactions are believed to contribute to the proinflammatory and prothrombotic…”
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The High-Affinity Chymotrypsin Inhibitor Eglin C Poorly Inhibits Human Chymotrypsin-Like Protease: Gln192 and Lys218 Are Key Determinants by Németh, Bálint Zoltán, Kiss, Bence, Sahin-Tóth, Miklós, Magyar, Csaba, Pál, Gábor

“…Eglin C, a small protein from the medicinal leech, has been long considered a general high-affinity inhibitor of chymotrypsins and elastases. Here, we…”
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Development of WO3–Nafion Based Membranes for Enabling Higher Water Retention at Low Humidity and Enhancing PEMFC Performance at Intermediate Temperature Operation by Selim, Asmaa, Szijjártó, Gábor Pál, Románszki, Loránd, Tompos, András

“…The proton exchange membrane (PEM) represents a pivotal material and a key challenge in developing fuel cell science and hydrogen technology. Nafion is the…”
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DYNLL/LC8: a light chain subunit of the dynein motor complex and beyond by Rapali, Péter, Szenes, Áron, Radnai, László, Bakos, Anita, Pál, Gábor, Nyitray, László

“…The LC8 family members of dynein light chains (DYNLL1 and DYNLL2 in vertebrates) are highly conserved ubiquitous eukaryotic homodimer proteins that interact,…”
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SARS-CoV-2 Nucleocapsid Protein Is Not Responsible for Over-Activation of Complement Lectin Pathway by Kocsis, Andrea, Bartus, Dalma, Hirsch, Edit, Józsi, Mihály, Hajdú, István, Dobó, József, Balczer, Júlia, Pál, Gábor, Gál, Péter

“…The nucleocapsid (N) protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a viral structural protein that is abundant in the circulation…”
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Comment on "Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway" by Gál, Péter, Dobó, József, Pál, Gábor

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Novel MASP-2 inhibitors developed via directed evolution of human TFPI1 are potent lectin pathway inhibitors by Szakács, Dávid, Kocsis, Andrea, Szász, Róbert, Gál, Péter, Pál, Gábor

“…The lectin pathway (LP) of the complement system is an important antimicrobial defense mechanism, but it also contributes significantly to ischemia reperfusion…”
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Arg236 in human chymotrypsin B2 (CTRB2) is a key determinant of high enzyme activity, trypsinogen degradation capacity, and protection against pancreatitis by Németh, Bálint Zoltán, Demcsák, Alexandra, Micsonai, András, Kiss, Bence, Schlosser, Gitta, Geisz, Andrea, Hegyi, Eszter, Sahin-Tóth, Miklós, Pál, Gábor

“…Pancreatic chymotrypsins (CTRs) are digestive proteases that in humans include CTRB1, CTRB2, CTRC, and CTRL. The highly similar CTRB1 and CTRB2 are the…”
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MASP-1 of the complement system alters fibrinolytic behaviour of blood clots by Jenny, Lorenz, Noser, Danilo, Larsen, Julie Brogaard, Dobó, József, Gál, Péter, Pál, Gábor, Schroeder, Verena

“…•MASP-1 accelerated the lysis of whole blood clots assessed by thrombelastometry.•Inhibition of endogenous MASP-1 prolonged plasma clot lysis in a…”
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MASP-1 and MASP-2 Do Not Activate Pro-Factor D in Resting Human Blood, whereas MASP-3 Is a Potential Activator: Kinetic Analysis Involving Specific MASP-1 and MASP-2 Inhibitors by Oroszlán, Gábor, Kortvely, Elod, Szakács, Dávid, Kocsis, Andrea, Dammeier, Sascha, Zeck, Anne, Ueffing, Marius, Závodszky, Péter, Pál, Gábor, Gál, Péter, Dobó, József

“…It had been thought that complement factor D (FD) is activated at the site of synthesis, and only FD lacking a propeptide is present in blood. The serum of…”
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Synergy of protease-binding sites within the ecotin homodimer is crucial for inhibition of MASP enzymes and for blocking lectin pathway activation by Nagy, Zoltán Attila, Héja, Dávid, Bencze, Dániel, Kiss, Bence, Boros, Eszter, Szakács, Dávid, Fodor, Krisztián, Wilmanns, Matthias, Kocsis, Andrea, Dobó, József, Gál, Péter, Harmat, Veronika, Pál, Gábor

“…Ecotin is a homodimeric serine protease inhibitor produced by many commensal and pathogenic microbes. It functions as a virulence factor, enabling survival of…”
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Novel linear motif filtering protocol reveals the role of the LC8 dynein light chain in the Hippo pathway by Erdős, Gábor, Szaniszló, Tamás, Pajkos, Mátyás, Hajdu-Soltész, Borbála, Kiss, Bence, Pál, Gábor, Nyitray, László, Dosztányi, Zsuzsanna

“…Protein-protein interactions (PPIs) formed between short linear motifs and globular domains play important roles in many regulatory and signaling processes but…”
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Novel, Fluorine-Free Membranes Based on Sulfonated Polyvinyl Alcohol and Poly(ether-block-amide) with Sulfonated Montmorillonite Nanofiller for PEMFC Applications by Al-Mashhadani, Manhal H Ibrahim, Szijjártó, Gábor Pál, Sebestyén, Zoltán, Károly, Zoltán, Mihály, Judith, Tompos, András

“…Novel blend membranes containing S-PVA and PEBAX 1657 with a blend ratio of 8:2 (referred to as SPP) were prepared using a solution-casting technique. In the…”
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Substrate specificity of human chymotrypsin-like protease (CTRL) characterized by phage display-selected small-protein inhibitors by Németh, Bálint Zoltán, Nagy, Zoltán Attila, Kiss, Bence, Gellén, Gabriella, Schlosser, Gitta, Demcsák, Alexandra, Geisz, Andrea, Hegyi, Eszter, Sahin-Tóth, Miklós, Pál, Gábor

“…Chymotrypsin-like protease (CTRL) is one of the four chymotrypsin isoforms expressed in the human exocrine pancreas. Human genetic and experimental evidence…”
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Directed Evolution of Canonical Loops and Their Swapping between Unrelated Serine Proteinase Inhibitors Disprove the Interscaffolding Additivity Model by Boros, Eszter, Sebák, Fanni, Héja, Dávid, Szakács, Dávid, Zboray, Katalin, Schlosser, Gitta, Micsonai, András, Kardos, József, Bodor, Andrea, Pál, Gábor

“…Reversible serine proteinase inhibitors comprise 18 unrelated families. Each family has a distinct representative structure but contains a surface loop that…”
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Overlapping Specificity of Duplicated Human Pancreatic Elastase 3 Isoforms and Archetypal Porcine Elastase 1 Provides Clues to Evolution of Digestive Enzymes by Boros, Eszter, Szabó, András, Zboray, Katalin, Héja, Dávid, Pál, Gábor, Sahin-Tóth, Miklós

“…Chymotrypsin-like elastases (CELAs) are pancreatic serine proteinases that digest dietary proteins. CELAs are typically expressed in multiple isoforms that can…”
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Stress and Anxiety among High School Adolescents: Correlations between Physiological and Psychological Indicators in a Longitudinal Follow-Up Study by Stromájer, Gábor Pál, Csima, Melinda, Iváncsik, Réka, Varga, Bernadett, Takács, Krisztina, Stromájer-Rácz, Tímea

“…Mental and psychological disorders are serious health problems worldwide. Anxiety among high school students can affect school performance, relationships, and…”
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