Search Results - "Ozinsky, A."

An Overlapping Protein-Coding Region in Influenza A Virus Segment 3 Modulates the Host Response by Jagger, B. W., Wise, H. M., Kash, J. C., Walters, K.-A., Wills, N. M., Xiao, Y.-L., Dunfee, R. L., Schwartzman, L. M., Ozinsky, A., Bell, G. L., Dalton, R. M., Lo, A., Efstathiou, S., Atkins, J. F., Firth, A. E., Taubenberger, J. K., Digard, P.

“…Influenza A virus (IAV) infection leads to variable and imperfectly understood pathogenicity. We report that segment 3 of the virus contains a second open…”
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The response of partially confined right circular stainless steel cylinders to internal air-blast loading by Langdon, G.S., Ozinsky, A., Chung Kim Yuen, S.

“…This article presents the results of an experimental and numerical investigation into the response of partially confined right-circular stainless steel…”
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Cutting Edge: Functional Interactions Between Toll-Like Receptor (TLR) 2 and TLR1 or TLR6 in Response to Phenol-Soluble Modulin by Hajjar, Adeline M, O'Mahony, D. Shane, Ozinsky, Adrian, Underhill, David M, Aderem, Alan, Klebanoff, Seymour J, Wilson, Christopher B

“…Toll-like receptor (TLR) 2 and TLR4 play important roles in the early, innate immune response to microbial challenge. TLR2 is preferentially involved in the…”
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Transcriptional noise and cellular heterogeneity in mammalian macrophages by Ramsey, S, Ozinsky, A, Clark, A, Smith, K.D, de Atauri, P, Thorsson, V, Orrell, D, Bolouri, H

“…Transcriptional noise is known to play a crucial role in heterogeneity in bacteria and yeast. Mammalian macrophages are known to exhibit cell-to-cell variation…”
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Toll-like receptor-5 and the innate immune response to bacterial flagellin by Smith, K D, Ozinsky, A

“…The innate immune system identifies the presence of infection by detecting structures that are unique to microbes and that are not expressed in the host. The…”
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Involvement of the AP-1 adaptor complex in early steps of phagocytosis and macropinocytosis by Lefkir, Yaya, Malbouyres, Marilyne, Gotthardt, Daniel, Ozinsky, Adrian, Cornillon, Sophie, Bruckert, Franz, Aderem, Alan A, Soldati, Thierry, Cosson, Pierre, Letourneur, François

“…The best described function of the adaptor complex-1 (AP-1) is to participate in the budding of clathrin-coated vesicles from the trans-Golgi network and…”
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Toll-like receptors: key mediators of microbe detection by Underhill, David M, Ozinsky, Adrian

“…Toll-like receptors are pattern-recognition receptors that have key roles in detecting microbes and initiating inflammatory responses. Recently, a host of new…”
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PHAGOCYTOSIS OF MICROBES: Complexity in Action by Underhill, David M, Ozinsky, Adrian

“…The phagocytic response of innate immune cells such as macrophages is defined by the activation of complex signaling networks that are stimulated by microbial…”
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The air-blast response of sandwich panels with composite face sheets and polymer foam cores: Experiments and predictions by Langdon, G.S., Karagiozova, D., von Klemperer, C.J., Nurick, G.N., Ozinsky, A., Pickering, E.G.

“…The paper reports on an experimental and numerical investigation into the response of sandwich panels, with PVC foam cores and glass fibre reinforced vinyl…”
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A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease by Hawn, Thomas R, Verbon, Annelies, Lettinga, Kamilla D, Zhao, Lue Ping, Li, Shuying Sue, Laws, Richard J, Skerrett, Shawn J, Beutler, Bruce, Schroeder, Lea, Nachman, Alex, Ozinsky, Adrian, Smith, Kelly D, Aderem, Alan

“…Although Toll-like receptors (TLRs) are critical mediators of the immune response to pathogens, the influence of polymorphisms in this gene family on human…”
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The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5 by Aderem, Alan, Hayashi, Fumitaka, Smith, Kelly D, Ozinsky, Adrian, Hawn, Thomas R, Yi, Eugene C, Goodlett, David R, Eng, Jimmy K, Akira, Shizuo, Underhill, David M

“…The innate immune system recognizes pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, but not on the host. Toll-like…”
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The Repertoire for Pattern Recognition of Pathogens by the Innate Immune System is Defined by Cooperation between Toll-Like Receptors by Ozinsky, A, Underhill, D M, Fontenot, J D, Hajjar, A M, Smith, K D, Wilson, C B, Schroeder, L, Aderem, A

“…Toll-like receptors (TLRs) have been shown to participate in the recognition of pathogens by the innate immune system, but it is not clear how a restricted…”
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Pyogenic Bacterial Infections in Humans with IRAK-4 Deficiency by Picard, Capucine, Puel, Anne, Bonnet, Marion, Ku, Cheng-Lung, Bustamante, Jacinta, Yang, Kun, Soudais, Claire, Dupuis, Stéphanie, Feinberg, Jacqueline, Fieschi, Claire, Elbim, Carole, Hitchcock, Remi, Lammas, David, Davies, Graham, Al-Ghonaium, Abdulaziz, Al-Rayes, Hassan, Al-Jumaah, Sulaiman, Al-Hajjar, Sami, Al-Mohsen, Ibrahim Zaid, Frayha, Husn H., Rucker, Rajivi, Hawn, Thomas R., Aderem, Alan, Tufenkeji, Haysam, Haraguchi, Soichi, Day, Noorbibi K., Good, Robert A., Gougerot-Pocidalo, Marie-Anne, Ozinsky, Adrian, Casanova, Jean-Laurent

“…Members of the Toll-like receptor (TLR) and interleukin-1 receptor (IL-1R) superfamily share an intracytoplasmic Toll-IL-1 receptor (TIR) domain, which…”
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Human TLR-7-, -8-, and -9-Mediated Induction of IFN-α/β and -λ Is IRAK-4 Dependent and Redundant for Protective Immunity to Viruses by Yang, Kun, Puel, Anne, Zhang, Shenying, Eidenschenk, Céline, Ku, Cheng-Lung, Casrouge, Armanda, Picard, Capucine, von Bernuth, Horst, Senechal, Brigitte, Plancoulaine, Sabine, Al-Hajjar, Sami, Al-Ghonaium, Abdulaziz, Maródi, László, Davidson, Donald, Speert, David, Roifman, Chaim, Garty, Ben-Zion, Ozinsky, Adrian, Barrat, Franck J., Coffman, Robert L., Miller, Richard L., Li, Xiaoxia, Lebon, Pierre, Rodriguez-Gallego, Carlos, Chapel, Helen, Geissmann, Frédéric, Jouanguy, Emmanuelle, Casanova, Jean-Laurent

“…Five TLRs are thought to play an important role in antiviral immunity, sensing viral products and inducing IFN-α/β and -λ. Surprisingly, patients with a defect…”
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Toll-Like Receptor-2 Mediates Mycobacteria-Induced Proinflammatory Signaling in Macrophages by Underhill, David M., Ozinsky, Adrian, Smith, Kelly D., Aderem, Alan

“…The recognition of mycobacterial cell wall components causes macrophages to secrete tumor necrosis factor α (TNF-α) and other cytokines that are essential for…”
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The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens by Aderem, Alan, Underhill, David M, Ozinsky, Adrian, Hajjar, Adeline M, Stevens, Anne, Wilson, Christopher B, Bassetti, Michael

“…Macrophages orchestrate innate immunity by phagocytosing pathogens and coordinating inflammatory responses. Effective defence requires the host to discriminate…”
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Leptospiral lipopolysaccharide activates cells through a TLR2-dependent mechanism by Tapping, Richard I, Mathison, John C, Kravchenko, Vladimir, Tobias, Peter S, Kirschning, Carsten J, Chuang, Tsung-Hsien, Godowski, Paul J, Werts, Catherine, Haake, David A, Hayashi, Fumitaka, Wagner, Hermann, Saint Girons, Isabelle, Aderem, Alan, Ozinsky, Adrian, Ulevitch, Richard J, Underhill, David M

“…Leptospira interrogans are zoonotic pathogens that have been linked to a recent increased incidence of morbidity and mortality in highly populated tropical…”
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Binding specificity of Toll‐like receptor cytoplasmic domains by Brown, Victoria, Brown, Rachel A., Ozinsky, Adrian, Hesselberth, Jay R., Fields, Stanley

“…MyD88 participates in signal transduction by binding to the cytoplasmic Toll/IL‐1 receptor (TIR) domains of activated Toll‐like receptors (TLR). Yeast…”
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Differential Role of MyD88 in Macrophage-Mediated Responses to Opportunistic Fungal Pathogens by MARR, Kieren A, ARUNMOZHI BALAJEE, S, HAWN, Thomas R, OZINSKY, Adrian, PHAM, Uyenvy, AKIRA, Shizuo, ADEREM, Alan, LILES, W. Conrad

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Co-operative induction of pro-inflammatory signaling by Toll-like receptors by Ozinsky, A, Smith, K D, Hume, D, Underhill, D M

“…Toll-like receptors (TLRs) mediate detection of a broad range of pathogens and pathogen-derived products including LPS, peptidoglycan, bacterial lipopeptides,…”
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