Search Results - "Ozgurses, Mete Emir"

DNA replication is highly resilient and persistent under the challenge of mild replication stress by Mocanu, Camelia, Karanika, Eleftheria, Fernández-Casañas, María, Herbert, Alex, Olukoga, Tomisin, Özgürses, Mete Emir, Chan, Kok-Lung

“…Mitotic DNA synthesis (MiDAS) has been proposed to restart DNA synthesis during mitosis because of replication fork stalling in late interphase caused by mild…”
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A Meta-Analysis: Identification of Common Mir-145 Target Genes that have Similar Behavior in Different GEO Datasets by Pashaei, Elnaz, Guzel, Esra, Ozgurses, Mete Emir, Demirel, Goksun, Aydin, Nizamettin, Ozen, Mustafa

“…MicroRNAs, which are small regulatory RNAs, post-transcriptionally regulate gene expression by binding 3'-UTR of their mRNA targets. Their deregulation has…”
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ASCT2 is a major contributor to serine uptake in cancer cells by Conger, Kelly O., Chidley, Christopher, Ozgurses, Mete Emir, Zhao, Huiping, Kim, Yumi, Semina, Svetlana E., Burns, Philippa, Rawat, Vipin, Lietuvninkas, Lina, Sheldon, Ryan, Ben-Sahra, Issam, Frasor, Jonna, Sorger, Peter K., DeNicola, Gina M., Coloff, Jonathan L.

“…The non-essential amino acid serine is a critical nutrient for cancer cells due to its diverse biosynthetic functions. While some tumors can synthesize serine…”
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Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors by Choi, Bo-Hyun, Rawat, Vipin, Högström, Jenny, Burns, Philippa A., Conger, Kelly O., Ozgurses, Mete Emir, Patel, Jaymin M., Mehta, Tejas S., Warren, Angelica, Selfors, Laura M., Muranen, Taru, Coloff, Jonathan L.

“…A major challenge of targeting metabolism for cancer therapy is pathway redundancy, in which multiple sources of critical nutrients can limit the effectiveness…”
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Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy by Rawat, Vipin, DeLear, Patrick, Prashanth, Prarthana, Ozgurses, Mete Emir, Tebeje, Anteneh, Burns, Philippa A, Conger, Kelly O, Solís, Christopher, Hasnain, Yasir, Novikova, Anna, Endress, Jennifer E, González-Sánchez, Paloma, Dong, Wentao, Stephanopoulos, Greg, DeNicola, Gina M, Harris, Isaac S, Sept, David, Mason, Frank M, Coloff, Jonathan L

“…The nonphysiological nutrient levels found in traditional culture media have been shown to affect numerous aspects of cancer cell physiology, including how…”
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