Search Results - "Ozgenc, Emre"
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Protein and Gene Delivery Systems for Neurodegenerative Disorders: Where Do We Stand Today?
Published in Pharmaceutics (01-11-2022)“…It has been estimated that every year, millions of people are affected by neurodegenerative disorders, which complicate their lives and their caregivers’…”
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Radiolabeling, Quality Control, and Cell Binding Studies of New 99mTc-Labeled Bisphosphonates: 99mTc-Ibandronate Sodium
Published in Turkish journal of pharmaceutical sciences (01-04-2023)“…Objectives: Early detection of bone cancer is critical for treating symptoms, minimizing pain, and increasing overall quality of life. It is critical to…”
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3
Recent developments in cancer therapy and diagnosis
Published in Journal of pharmaceutical investigation (01-07-2020)“…Background The cancer is serious health problem and leading cause of death in the world. Area covered There have intensively studied for diagnosis and therapy…”
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4
An Innovative Formulation Based on Nanostructured Lipid Carriers for Imatinib Delivery: Pre-Formulation, Cellular Uptake and Cytotoxicity Studies
Published in Nanomaterials (Basel, Switzerland) (13-01-2022)“…Imatinib (IMT) is a tyrosine kinase enzyme inhibitor and extensively used for the treatment of gastrointestinal stromal tumors (GISTs). A nanostructured lipid…”
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The effect of radiolabeled nanostructured lipid carrier systems containing imatinib mesylate on NIH-3T3 and CRL-1739 cells
Published in Drug delivery (01-01-2020)“…The aim of current study is to develop new nanostructured lipid carrier systems (NLCSs) containing imatinib mesylate (IMT) and evaluate their targeting…”
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Polymer based Gels: Recent and Future Applications in Drug Delivery Field
Published in Current drug delivery (01-01-2023)“…Currently, there is ongoing research in the pharmaceutical technology field to develop innovative drug delivery systems with improved therapeutic efficacy…”
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7
Applying Quality by Design Principles in the Development and Preparation of a New Radiopharmaceutical: Technetium-99m-Imatinib Mesylate
Published in ACS omega (17-03-2020)“…The clinical impact and accessibility of 99mTc tracers for cancer diagnosis would be greatly enhanced by the availability of a new, simple, and easy labeling…”
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8
Pre-clinic study of radiopharmaceutical for Covid-19 inactivation: Dose distribution with Monte Carlo Simulation
Published in Applied radiation and isotopes (01-10-2022)“…Monte Carlo simulation method and Nuclear Medicine MIRD method were used to evaluate the effect of radiopharmaceuticals on Covid-19 disease. The mean absorbed…”
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68 Ga-labeled, imatinib encapsulated, theranostic liposomes: Formulation, characterization, and in vitro evaluation of anticancer activity
Published in Drug development research (01-02-2024)“…Cancer is still a global health problem. Among cancer types, breast cancer is the most frequently diagnosed one, and it causes a high mortality rate if not…”
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10
68Ga‐labeled, imatinib encapsulated, theranostic liposomes: Formulation, characterization, and in vitro evaluation of anticancer activity
Published in Drug development research (01-02-2024)“…Cancer is still a global health problem. Among cancer types, breast cancer is the most frequently diagnosed one, and it causes a high mortality rate if not…”
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99mTc-Labeled, Colistin Encapsulated, Theranostic Liposomes for Pseudomonas aeruginosa Infection
Published in AAPS PharmSciTech (10-03-2023)“…Infectious diseases are still the major issue not only due to antibiotic resistance but also causing deaths if not diagnosed at early-stages. Different…”
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12
Evaluation of F-18 FDG radiopharmaceuticals through Molecular Docking and radiation effects
Published in Applied radiation and isotopes (01-01-2023)Get full text
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13
99m Tc-labeled, tofacitinib citrate encapsulated chitosan microspheres loaded in situ gel formulations for intra-articular treatment of rheumatoid arthritis
Published in Drug development research (01-08-2024)“…Inflammatory diseases including rheumatoid arthritis are major health problems. Although different techniques and drugs are clinically available for the…”
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14
99mTc‐labeled, tofacitinib citrate encapsulated chitosan microspheres loaded in situ gel formulations for intra‐articular treatment of rheumatoid arthritis
Published in Drug development research (01-08-2024)“…Inflammatory diseases including rheumatoid arthritis are major health problems. Although different techniques and drugs are clinically available for the…”
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15
Radiolabeled Trastuzumab Solid Lipid Nanoparticles for Breast Cancer Cell: in Vitro and in Vivo Studies
Published in ACS omega (30-08-2022)“…Radiolabeled trastuzumab (TRZ) loaded solid lipid nanoparticles (SLNs) were prepared by high shear homogenization and sonication techniques. The apoptosis…”
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16
99m Tc-Labeled, Colistin Encapsulated, Theranostic Liposomes for Pseudomonas aeruginosa Infection
Published in AAPS PharmSciTech (10-03-2023)“…Infectious diseases are still the major issue not only due to antibiotic resistance but also causing deaths if not diagnosed at early-stages. Different…”
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17
99mTc-exendin-4: Radiolabeling and quality control studies of glucagon-like peptide analog
Published in Experimental biomedical research (01-07-2022)“…Aim: Exendin-4 is a type 2 diabetes antidiabetic drug that is a peptide agonist of the glucagon-like peptide 1 receptor (GLP-1R). Up to date, different…”
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18
Radiolabeling efficiency and cell incorporation of chitosan nanoparticles
Published in Journal of drug delivery science and technology (01-10-2015)“…Cationic nanoparticles of CS were developed according to ionotropic gelation process as potential cancer cell targeting agent. CS nanoparticles (CSNP) (F1 and…”
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19
Comparative permeability studies with radioactive and nonradioactive risedronate sodium from self-microemulsifying drug delivery system and solution
Published in Drug development and industrial pharmacy (01-01-2015)“…The purpose of this work is to prepare a self-microemulsifying drug delivery system (SMEDDS) for risedronate sodium (RSD) and to compare the permeability with…”
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20
Radiolabeling and in vitro evaluation of .sup.99mTc-methotrexate on breast cancer cell line
Published in Journal of radioanalytical and nuclear chemistry (01-01-2016)“…In the present study .sup.99mTc-MTX was prepared with high labeling yield by a new simple and easy formulation method. According to cell culture studies,…”
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